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The article presents a study which examined the special sugar expression lectin-histochemically on the fundamental settlement sites of indigenous bacteria throughout the rat alimentary tract. The special sugars were found to be expressed on the most luminal portions of mucosae as exclusive epithelial cell-shedding sites and that sugar expression is different among the various segments of the rat alimentary tract. It is concluded that the site differences might indicate differences in resident bacterial species in the alimentary tract.

The article focuses on one study which examines the regulatory effects of epithelial kinetics on indigenous bacterial proliferation in the large intestine. 30 seven-week old male Wistar rats purchased from Japan was included in the study, in which their epithelial cells in their proximal colon and middle colon were compared. Methods such as immunohistochemical detection, histoplanimetry and statistical analysis were conducted. After data analysis, it was revealed that the lifespan, migration and proliferation rate of epithelial cells were different depending on their location in colon.

The article presents a study that investigates the spatial relationship between mucosal lymphatic follicles (LF) distribution and bacterial colonies expansion across the alimentary tract of 19 male Wistar rats aged 7 weeks. These rats were kept in a normal laboratory housing conditions with access to food and water. Results revealed that the constant binding sites of indigenous bacteria (IB) are areas around the apices of intestinal villi in the small intestine and the most luminal mucosa in the large intestine, which are also the effete epithelial cells' shedding sites at late apoptotic stage. Moreover, the intestinal crypts lumina were filled with IB from cecum to proximal colon, however, no colonization of IB at intestinal crypts in the distal colon and rectum was detected.