1. Pheochromocytoma (PHEO) and Paraganglioma (PGL)
- Author
-
Pacak, Karel and Taïeb, David
- Subjects
11C-hydroxy-ephedrine ,177Lu-DOTATATE ,18F-FDOPA ,CNV detection ,EPAS1 ,FGF21 ,GAPP ,GTV ,HIF ,NET ,NF1 ,PASS ,PCC ,PET ,PET-CT ,PGL ,PPGL ,PRRT ,SDHB ,SDHD ,T cell ,TCA cycle ,VHL ,adaptive immunity ,adrenal incidentaloma ,adrenal tumor ,adrenocortical carcinoma ,adrenomedullary function ,angiogenesis ,arrhythmia ,average real variability ,blood pressure variability ,calorimetry ,carotid body ,catecholamine ,catecholamines ,chromogranin A ,chromosomal alteration ,comparative genomics ,cryoablation ,diabetes mellitus ,dog ,ectopic secretion ,energy metabolism ,erythropoietin ,fluorescence imaging ,germline mutation ,global longitudinal strain ,head and neck ,hereditary ,histology ,hypertension ,hypotension ,hypoxia ,hypoxia-inducible factor ,immunohistochemistry ,immunotherapy ,inflammation ,innate immunity ,lL-6 ,meta-analysis ,metanephrines ,metastatic ,metastatic OR malignant pheochromocytoma ,minimally invasive procedure ,mitochondria ,mortality ,mouse pheochromocytoma cells ,mutation ,n/a ,neural crest ,neuroendocrine ,neuroendocrine tumor ,neurogenesis ,neutrophil ,next-generation sequencing ,normetanephrines ,obesity ,pan-cancer analysis ,paraganglioma ,pathogen-associated molecular patterns ,peptide receptor radiotherapy ,percutaneous ablation ,percutaneous ethanol injection ,pheochromocytoma ,pheochromocytoma and paraganglioma ,phosphorylation tyrosine hydroxylase ,polycythemia ,postoperative ,pseudohypoxia ,radiofrequency ablation ,radiosensitization ,radiotherapy ,somatostatinoma ,speckle-tracking echocardiography ,spheroids ,sporadic ,stem-like tumor cells ,subclinical systolic dysfunction ,succinate dehydrogenase ,targeted therapy ,therapy resistance ,toll-like receptor ,transgenic mice ,vasculogenesis ,weighted standard deviation ,xenograft - Abstract
Summary: This book outlines some new advances in genetics, clinical evaluation, localization, therapy (newly including immunotherapy) of pheochromocytoma and paraganglioma including their metastatic counterparts. Well-known and experienced clinicians and scientists contributed to this book to include some novel approaches to these tumors. This book will serve to various health care professionals from different subspecialties, but mainly oncologists, endocrinologists, endocrine surgeons, pediatricians, and radiologists. This book shows that the field of pheochromocytoma/paraganglioma is evolving and a significant progress has been made in last 5 years requiring that health care professionals and scientists will learns new information and implement it in their clinical practice or scientific work, respectively. This book should not be missed by anybody who is focusing on neuroendocrine tumors, their newest evaluation and treatment.