1. Typical ultrasound features of various endometrial pathologies described using International Endometrial Tumor Analysis (IETA) terminology in women with abnormal uterine bleeding
- Author
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B. Van Calster, T. Van den Bosch, Ekaterini Domali, Tom Bourne, Attila Jakab, Marek Kudla, Jan Y Verbakel, Juan Luis Alcázar, Elisabeth Epstein, Alberto Rossi, F. P. G. Leone, Lil Valentin, Laure Wynants, Ligita Jokubkiene, Maria Angela Pascual, A. Votino, B. De Cock, C. Lanzani, Robert Fruscio, C. Van Pachterbeke, Dirk Timmerman, Povilas Sladkevicius, C. Van Holsbeke, RS: CAPHRI - R5 - Optimising Patient Care, Epidemiologie, Van den Bosch, T, Verbakel, J, Valentin, L, Wynants, L, De Cock, B, Pascual, M, Leone, F, Sladevicius, P, Alcazar, J, Votino, A, Fruscio, R, Lanzani, C, Van Holsbeke, C, Rossi, A, Jokubkiene, L, Kudla, M, Jakab, A, Domali, E, Epstein, E, Van Pachterbeke, C, Bourne, T, Van Calster, B, and Timmerman, D
- Subjects
POLYPS ,Technology ,diagnosis ,Atypical hyperplasia ,0302 clinical medicine ,Atypia ,SALINE INFUSION SONOGRAPHY ,Medicine ,030212 general & internal medicine ,Prospective Studies ,endometrium ,gray-scale ,Atypical Endometrial Hyperplasia ,Uterine Diseases ,030219 obstetrics & reproductive medicine ,Radiological and Ultrasound Technology ,OFFICE ,Radiology, Nuclear Medicine & Medical Imaging ,Obstetrics and Gynecology ,Obstetrics & Gynecology ,hyperplasia ,General Medicine ,ultrasonography ,Middle Aged ,CANCER ,diagnosi ,Leiomyoma ,transvaginal ultrasonography ,COLOR DOPPLER ,Median body ,Female ,Radiology ,Life Sciences & Biomedicine ,Adult ,SONOHYSTEROGRAPHY ,medicine.medical_specialty ,office ,03 medical and health sciences ,ieta ,color doppler ,saline infusion sonography ,leiomyoma ,THICKNESS ,Endometrial Polyp ,Humans ,cancer ,Radiology, Nuclear Medicine and imaging ,Science & Technology ,business.industry ,Endometrial cancer ,IETA ,Acoustics ,medicine.disease ,Endometrial hyperplasia ,Reproductive Medicine ,polyp ,Uterine Hemorrhage ,TRANSVAGINAL ULTRASONOGRAPHY ,business ,GRAY-SCALE - Abstract
OBJECTIVE: To describe the ultrasound features of different endometrial and other intracavitary pathologies inpre- and postmenopausal women presenting with abnormal uterine bleeding, using the International Endometrial Tumor Analysis (IETA) terminology. METHODS: This was a prospective observational multicenter study of consecutive women presenting with abnormal uterine bleeding. Unenhanced sonography with color Doppler and fluid-instillation sonography were performed. Endometrial sampling was performed according to each center's local protocol. The histological endpoints were cancer, atypical endometrial hyperplasia/endometrioid intraepithelial neoplasia (EIN), endometrial atrophy, proliferative or secretory endometrium, endometrial hyperplasia without atypia, endometrial polyp, intracavitary leiomyoma and other. For fluid-instillation sonography, the histological endpoints were endometrial polyp, intracavitary leiomyoma and cancer. For each histological endpoint, we report typical ultrasound features using the IETA terminology. RESULTS: The database consisted of 2856 consecutive women presenting with abnormal uterine bleeding. Unenhanced sonography with color Doppler was performed in all cases and fluid-instillation sonography in 1857. In 2216 women, endometrial histology was available, and these comprised the study population. Median age was 49 years (range, 19-92 years), median parity was 2 (range, 0-10) and median body mass index was 24.9 kg/m2 (range, 16.0-72.1 kg/m2 ). Of the study population, 843 (38.0%) women were postmenopausal. Endometrial polyps were diagnosed in 751 (33.9%) women, intracavitary leiomyomas in 223 (10.1%) and endometrial cancer in 137 (6.2%). None (0% (95% CI, 0.0-5.5%)) of the 66 women with endometrial thickness
- Published
- 2021