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Your search keyword '"Lee, Eun Je"' showing total 2 results
Start Over Author "Lee, Eun Je" Topic radiochemical separation
2 results on '"Lee, Eun Je"'

2. Medical radioisotope 89Zr production with RFT-30 cyclotron.

Author

Lee, Jun Young, Hur, Min Goo, Kong, Young Bae, Lee, Eun Je, Yang, Seung Dae, Choi, Pyeong Seok, and Park, Jeong Hoon

Subjects
CYCLOTRONS, RADIOISOTOPES, POSITRON emission tomography, NUCLEAR energy, NUCLEAR research, NUCLEAR medicine
Abstract

89Zr is an emerging radionuclide with promising application in nuclear medicine for the non-invasive diagnosis of various cancers with PET imaging. This paper would discuss optimization efforts in the production of 89Zr carried out at Accelerator Radioisotope Development Team, Korea Atomic Energy Research Institute. Optimized conditions reveal high production yields of 89Zr ~ 37 ± 1.4 MBq/µA using 89Y(p,n)89Zr, ~ 12.7 MeV of proton, and 35 µA using yttrium coin target with indigenously constructed 30 MeV Cyclotron (RFT-30). Besides, the production optimization, quality control, and biological behavior of [89Zr]Zr-oxalate, chloride and, DFO demonstrated promising results. [ABSTRACT FROM AUTHOR]

Published
2021
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