1. Interpolated functional manifold for functional near-infrared spectroscopy analysis at group level
- Author
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Shender-María Ávila-Sansores, Gustavo Rodríguez-Gómez, Felipe Orihuela-Espina, Ilias Tachtsidis, and Consejo Nacional de Ciencia y Tecnología (CONACYT) de México
- Subjects
Paper ,Classical group ,Surface (mathematics) ,topology ,Jaccard index ,Mean squared error ,Neuroscience (miscellaneous) ,01 natural sciences ,law.invention ,010309 optics ,03 medical and health sciences ,0302 clinical medicine ,0903 Biomedical Engineering ,law ,0103 physical sciences ,functional near-infrared spectroscopy ,Radiology, Nuclear Medicine and imaging ,Radial basis function ,Mathematics ,manifold ,Radiological and Ultrasound Technology ,1004 Medical Biotechnology ,functional connectivity ,Research Papers ,Group analysis ,connectivity analysis ,1109 Neurosciences ,Manifold (fluid mechanics) ,Algorithm ,030217 neurology & neurosurgery ,Interpolation - Abstract
Significance: Solutions for group-level analysis of connectivity from fNIRS observations exist, but groupwise explorative analysis with classical solutions is often cumbersome. Manifold-based solutions excel at data exploration, but there are infinite surfaces crossing the observations cloud of points. Aim: We aim to provide a systematic choice of surface for a manifold-based analysis of connectivity at group level with small surface interpolation error. Approach: This research introduces interpolated functional manifold (IFM). IFM builds a manifold from reconstructed changes in concentrations of oxygenated ΔcHbO2 and reduced ΔcHbR hemoglobin species by means of radial basis functions (RBF). We evaluate the root mean square error (RMSE) associated to four families of RBF. We validated our model against psychophysiological interactions (PPI) analysis using the Jaccard index (JI). We demonstrate the usability in an experimental dataset of surgical neuroergonomics. Results: Lowest interpolation RMSE was 1.26e − 4 ± 1.32e − 8 for ΔcHbO2 [A.U.] and 4.30e − 7 ± 2.50e − 13 [A.U.] for ΔcHbR. Agreement with classical group analysis was JI = 0.89 ± 0.01 for ΔcHbO2. Agreement with PPI analysis was JI = 0.83 ± 0.07 for ΔcHbO2 and JI = 0.77 ± 0.06 for ΔcHbR. IFM successfully decoded group differences [ANOVA: ΔcHbO2: F ( 2,117 ) = 3.07; p
- Published
- 2020