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Worldwide, many vaccines have been developed in response to the COVID-19 pandemic. Unilateral reactive axillary adenopathy related to the COVID-19 vaccine is a well-known occurrence. In addition, axillary edema has also been observed following COVID-19 vaccinations in patients undergoing breast MRI, and radiologists need to be aware of this possibility to avoid performing unnecessary work-up that can be costly to the health care system and be stressful for patients.

The pandemic caused by the new Coronavirus has changed the way patient care is provided worldwide. This review focuses on the description of the operational measures implemented in a breast imaging department in accordance with existing recommendations for the treatment of breast cancer during the COVID-19 pandemic to make optimal use of finite resources without interruption of essential imaging services for breast cancer patients. It will also apply during a second-wave of the pandemic, which, according to experts, is inevitable and requires us to be better prepared.