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Declines in cognitive performance, such as those seen in neurocognitive disorders (NCDs) are often associated with ageing. Both physical activity and cognitive training are common interventional strategies that can mitigate the decline in cognitive and physical performance. This review aims to (1) to evaluate the effects of Physio-Cognitive Dual-task Training (PCDT) intervention on cognition, physical performance, activities of daily living (ADL) and health-related quality of life (HRQoL) in pre-ageing and older adults with neurocognitive disorders, (2) explore the effects of covariates on intervention outcomes. A systematic search was conducted in eight databases. Cochrane's Risk of Bias Tool version 1 and GRADE criteria were used to assess risk of bias and certainty of evidence, respectively. Meta-analysis and meta-regression analyses were conducted using R software. Twenty-six randomized controlled trials involving 1,949 pre-ageing and older adults with NCDs were included in the meta-analysis. PCDT interventions had small-to-medium effect size on all cognition outcomes (g = 0.40-0.52) and instrumental ADL (g == 0.42), and a large effect size on HRQoL (g = 0.72). The quality of evidence was rated moderate to low for the outcome measures in pre-ageing and older adults with NCDs. These findings highlight the importance of PCDT interventions in preventing and slowing down cognitive impairment in pre-ageing and older adults. Registration: PROSPERO Number (CRD42020213962)., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier B.V. All rights reserved.)

Aims: To evaluate the effectiveness of technology‐based interventions in reducing psychological morbidities such as depressive symptomology, anxiety, burden and improving quality of life and self‐efficacy in informal caregivers of stroke survivors. Design: A systematic review and meta‐analysis. Data Sources: An extensive search was systematically undertaken at CENTRAL, PubMed, Embase, Scopus, CINHAL, Web of Science and PsycInfo until January 2021. Grey literature and dissertations were searched in Google Scholar, ProQuest & Scholarbank@NUS. Studies involving registered trials were retrieved from Clinicaltrials.gov and CENTRAL, respectively. Review Methods: Two reviewers independently screened the trials, conducted quality appraisal and extracted the data. Quality of the studies included in the review was assessed using Cochrane Risk of bias tool. Meta‐analysis was conducted using RevMan 5.4. Narrative synthesis was performed for studies where results could not be pooled statistically. The results were reported abiding Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. Results: This review included 15 trials with a total of 1276 informal caregivers of stroke survivors. Eleven trials were included in the meta‐analysis. Subgroup analyses revealed that technology‐based interventions with structured educational programs were statistically significant in reducing depressive symptoms (d = −0.27, 95% CI [−0.49 to −0.05], p =.02). Technology‐based interventions with structured educational programs <3‐month revealed significant effects (d = −0.31, 95% CI [−0.49 to −0.13], p =.0009). Results of narrative synthesis reported technology‐based intervention with face‐to‐face training minimized depressive symptoms of informal caregivers. Notably, there were no statistically significant effects on anxiety, burden, quality of life and self‐efficacy outcomes. Conclusion: Technology‐based interventions had beneficial effects in alleviating depressive symptoms among informal caregivers. Impact: Technology‐based interventions serve as a support mechanism for informal caregivers of stroke survivors who face time‐constrains. Further high‐quality randomized controlled trials are warranted to elucidate sustainability, optimal format and dosage of intervention. [ABSTRACT FROM AUTHOR]