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1. Peptide bond formation on the ribosome. Structural requirements for inhibition of protein synthesis and of release of peptides from peptidyl-tRNA on bacterial and mammalian ribosomes by aminoacyl and nucleotidyl analogues of puromycin.

Author

Harris RJ, Hanlon JE, and Symons RH

Subjects
Acyltransferases analysis, Amino Acids metabolism, Amino Acids pharmacology, Animals, Binding Sites, Carbon Isotopes, Cell-Free System, Escherichia coli cytology, Escherichia coli metabolism, In Vitro Techniques, Kinetics, Leucine metabolism, Nucleosides pharmacology, Nucleotides pharmacology, Peptide Biosynthesis, Phenylalanine metabolism, Phosphoric Acids pharmacology, Polynucleotides, Pyruvate Kinase, RNA, Messenger, Rabbits, Reticulocytes drug effects, Reticulocytes enzymology, Reticulocytes metabolism, Ribosomes drug effects, Ribosomes enzymology, Transferases metabolism, Bacterial Proteins biosynthesis, Protein Biosynthesis, Puromycin pharmacology, RNA, Transfer, Ribosomes metabolism
Published
1971
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