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Introduction: This study is about female nursing staff whose mission is to provide professional care to ailing patients, but who are also vulnerable to bullying, harassment, and even assault while they perform their duties. Objectives: The study attempts to describe the level of perceived workplace security among the nurses and investigate relationship between theoretically identified predictors and the perceived workplace security of nurses working in public hospitals in Lahore city. Study Design: Factors such as civility in co-worker behavior, clarity of norms of communication with co-workers, integrity and trust of the leaders, awareness of law and legal procedure related to harassment at work place and physical settings characteristics-including transparency and privacy at the workplace-were modeled through a cross-sectional research design as contributing towards workplace security of female nurses. Study Period: Oct 2015 to May, 2016. Methods: Multi-stage probability sampling was used to collect data from 317 respondents working in five public sector hospitals in Lahore city during first quarter of 2016. Zero-order correlation and multiple regression methods were used to analyze the data. Findings: Results showed that civility (B=.071, p<.000) in co-worker behavior, integrity (B=.185, p<.000) and trust of leaders (B=.059, p<.000) is the most potent factor influencing perceived workplace security of female nurses. Moreover, clear norms of communication (B=.169, p<.000) and privacy (B=.133, p<.000) at workplace also significantly influence their perceived workplace security. Transparency (B=.017, p>.05) in physical settings and awareness (B=-.014, p>.05)of law and legal procedures were found to be insignificant. Conclusion: It was concluded that setting clear work norms and leadership development in the areas of integrity and trust can play a substantial role in improving perception of workplace security in female nursing staff. Awareness of laws regarding harassment among nurses need to be increased through formal and concerted effort. [ABSTRACT FROM AUTHOR]