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Personalization is at the center of medical practice. With the sequencing of the genome, the rise in technologies and big data processing capacities, it was then envisioned in an even more precise way, for more targeted treatments on patients' distinctive features. In the last few years, prospects for this personalization went in the direction of public health. Beyond patients, the aim is thus to pursue the entire population, to identify and adjust action on the social, environmental, and biomedical factors that make individuals vulnerable in a health perspective. This is referred as personalized health. Its objective is to better understand the interactions between these factors for a more efficient approach of healthcare and interventions on the social conditions for maintaining the good health of all., Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.