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The article details how the introduction of penicillin in 1943 as treatment for syphilis influenced venereology and sexual healthcare delivery systems in mid-20th century Great Britain. Topics discussed include the change in public perception that venereal disease is a public threat and deserves fewer resources for control, the drastic reduction in syphilis cases in the late 1940s and early 1950s, and the factors behind the rise in syphilis cases during the late 1950s and early 1960s.

The article describes how the introduction of penicillin revolutionized venereology care in Great Britain from 1944 to 1964.