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On the base of clinical psychological and electrophysiological studies of 34 patients with primary manifestations of brain circulation insufficiency good tolerance and high efficiency of Tanakan course treatment (3 x 40 mg/day for 3 months) were showen. Tanakan decreased manifestations of clinical syndrome, improved psychological functions and electrophysiological parameters. Prospective study supported the stability of positive changes in the status of patients for 12 months after Tanakan course treatment.

By means of pharmacoepidemiologic method the analysis of therapy in nonselective ambulatory cohort of mentally ill 60-95 year old patients was performed during 5 months. Each patient had an epidemiological record, in which the main demographic, clinical data as well as all the drugs prescribed and the regimen of their administration were registered. All spectrum of psychotropic drugs was used for treatment of aged patients. In 80% of the cases tranquilizers and hypnotic drugs were prescribed, while neuroleptics were prescribed in 64% of the patients, vasotropic and nootropic preparations--in 32%, antidepressants--in 28%, antiparkinsonic drugs--in 17%, normothymics--in 7%, anticonvulsants--in 2% of the cases. Monotherapy was used in 24% of the cases, two psychotropic drugs were prescribed simultaneously in 31% of the patients, 3--in 23% and 4 drugs--in 17% of the patients. Age factor was not significant for the choice of the drug.