1. Incidence, predictors and prognostic value of permanent pacemaker implantation following sutureless valve implantation in low-risk aortic stenosis patients.
- Author
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Vilalta, Victoria, Cediel, Germán, Mohammadi, Siamak, López, Helena, Kalavrouziotis, Dimitri, Resta, Helena, Dumont, Eric, Voisine, Pierre, Philippon, François, Escabia, Claudia, Borrellas, Andrea, Alperi, Alberto, Bayes-Genis, Antoni, and Rodes-Cabau, Josep
- Subjects
CARDIAC pacemakers ,HEART valve prosthesis implantation ,AORTIC stenosis ,PROGNOSTIC models ,BUNDLE-branch block ,PROGNOSIS ,AORTIC valve transplantation ,AORTIC valve insufficiency - Abstract
Open in new tab Download slide OBJECTIVES Sutureless aortic valve replacement (SU-SAVR) has been associated with higher rates of permanent pacemaker (PPM) compared with conventionally implanted aortic bioprostheses. The purpose of this study was to determine the incidence, predictors and mid-term prognostic impact of PPM after Perceval (Livanova, London, UK) SU-SAVR in low-risk patients. METHODS A total of 400 consecutive low-risk (EuroSCORE II < 4%) patients without prior pacemaker who underwent surgical aortic valve replacement with the Perceval prosthesis from 2013 to 2019 in 2 centres were included. Baseline, clinical and electrocardiographic parameters, procedural characteristics and follow-up data were collected. RESULTS PPM was required in 36 (9%) patients after SU-SAVR, with a median time between the procedure and PPM implantation of 7.5 (4.5–10.5) days. Older age and prior right bundle branch block (RBBB) were associated with an increased risk of PPM (P < 0.05 for all), but only baseline RBBB was found to be an independent predictor of new PPM requirement (odds ratio: 2.60, 95% confidence interval: 1.15–5.81; P = 0.022). At a median follow-up of 3.4 (2.3–4.5) years, there were no differences between groups in mortality (PPM: 36%, no PPM: 22%, P = 0.105) or heart failure rehospitalization (PPM: 25%, no PPM: 21%, P = 0.839). CONCLUSIONS About 1 out of 10 low-risk patients with aortic stenosis undergoing SU-SAVR with the Perceval prosthesis required PPM implantation. Prior RBBB determined an increased risk (close to 3-fold) of PPM following the procedure. PPM was not associated with a higher risk of clinical events at 3-year follow-up. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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