Search

Copyright of Ginecologia.ro is the property of MEDICHUB MEDIA, S.R.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Poor ovarian response in assisted reproductive techniques is defined by an association of clinical features, hormonal markers and ultrasound parameters that have been grouped by ESHRE under the name of Bologna criteria. The incidence of poor ovarian responders among infertile wo men has been estimated within the range of 9% to 22%. Poor response to controlled ovarian hyperstimulation reflects advanced ovarian aging, which may be associated with early vascular aging. The aim of this research is to identify whether poor perinatal outcomes and pregnancy complications are higher among women with poor ovarian response. [ABSTRACT FROM AUTHOR]

Copyright of Ginecologia.ro is the property of MEDICHUB MEDIA, S.R.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Twin-twin transfusion syndrome (TTTS) is a disorder present in complicated monochorionic twin pregnancies. Best estimated, the prevalence of TTTS is 9% to 15% of monochorionic diamniotic twin pregnancies and 6% of monoamniotic twin pregnancies. The main requirement for the development of this pathology is the existence of arteriovenous anastomoses which allows blood to migrate from one fetus to the other. This vascular anomaly is seen only in monochorionic twin pregnancies. TTTS is generally diagnosed on an ultrasound examination performed in the early-to-mid second trimester and the monitorization is recommended to be done at two-week intervals. The five classic stages of disease used in TTTS are based on findings from two-dimensional and Doppler ultrasound, also called the Quintero Classification System. The differential diagnosis of this pathology can be a challenging one, due to the large number of disorders which can mirror TTTS: prelabor preterm rupture of membranes (PPROM) of one sac, intrauterine infection, congenital anomalies, selective fetal growth restriction (sFGR), and twin anemia polycythemia sequence (TAPS). When deciding the best therapeutic approach in TTTS, the stage of disorder, maternal signs and symptoms, the gestational age and the availability of requisite technical expertise must be taken into consideration. The three primary approaches when dealing with TTTS are expectant management, fetoscopic laser ablation of anastomotic vessels and amnioreduction. [ABSTRACT FROM AUTHOR]

Although in recent years the number of pregnancies obtained through in vitro fertilization (IVF) has increased significantly, a higher incidence of complications has been identified in this group. The widespread development and use of IVF has led to an increasing rate of multiple pregnancies and thus their associated complications. However, whether these complications occur due to assisted reproduction or infertility problems remains to be elucidated. In the present study, a comparison was made of IVF pregnancies with spontaneous conception, and the risk of obstetric and neonatal complications was assessed. An ambispective observational cohort study was carried out between January 2017 and October 2021 at Elias University Emergency Hospital, Romania. The exposed cohort included 132 IVF pregnancies and the control cohort included 157 spontaneous pregnancies. The IVF group included 110 pregnancies with fresh embryo-transfer and 22 pregnancies with cryopreserved embryo-transfer. Obstetric, perinatal and neonatal complications were analysed by multivariable logistic analysis. The results showed that, IVF pregnancies had a higher risk of pregnancy-induced hypertension (OR=6.42, 95% CI=1.72-23.92) and placental abnormalities (OR=5.49, 95% CI=1.07-28.17). Neonates obtained through IVF had a higher risk of prematurity (OR=6.52, 95% CI=2.99-14.20), low birth weight (LBW) (OR=17.18, 95% CI=7.06-41.87), small for gestational age (OR=4.10, 95% CI=1.95-8.59) and were more frequently hospitalized in the Neonatal Intensive Care Unit (NICU) (OR=11.91, 95% CI=5.72-24.81). Nulliparous women were associated with an increased risk of NICU admission (OR=0.46, 95% CI=0.25-0.88) and risk of LBW (OR=0.37, 95% CI=0.19-0.75). Maternal age ≥35 years had no influence as a confounding variable. In conclusion, this cohort study showed that IVF pregnancies have a higher risk of obstetric and neonatal complications than pregnancies obtained by spontaneous conception. [ABSTRACT FROM AUTHOR]

Copyright of Ginecologia.ro is the property of MEDICHUB MEDIA, S.R.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)