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3 results on '"Kadayifçi O"'

2. Endogenous digoxin-immunoreactive substance in normal and preeclamptic pregnancies.

Author

Loğoğlu G, Erdoğan S, Ozgünen FT, Doğan A, Ozgünen T, and Kadayifçi O

Subjects
Adolescent, Adult, Blood Pressure, Cardenolides, Female, Gestational Age, Humans, Pre-Eclampsia physiopathology, Prospective Studies, Sodium-Potassium-Exchanging ATPase antagonists & inhibitors, Blood Proteins physiology, Digoxin, Pre-Eclampsia blood, Pregnancy blood, Saponins
Abstract

Aims: To determine the potential use of a digoxin-immunoreactive substance in the prediction of preeclampsia, to study the relationship between serum levels of this substance and gestational age, and to evaluate the correlation between this substance and blood pressure findings in preeclamptic pregnancies., Methods: Serum digoxin-immunoreactive substance concentrations were measured by RIA (double antibody radioimmunoassay) in normotensive (n = 14) and preeclamptic (n = 17) pregnant women in their third trimesters. Statistical evaluation was performed with the Mann-Whitney U-test and correlation-regression analysis., Results: The mean (+/- S.E.) digoxin-immunoreactive substance levels in the normal and preeclamptic patients were 0.29 +/- 0.06 and 0.31 +/- 0.05 ng/ml, respectively, the slightly higher level in the hypertensive group being statistically non-significant. Serum digoxin-immunoreactive substance levels did not demonstrate good correlation with gestational age and systolic blood pressure in preeclamptic pregnancies., Conclusions: An endogenous digoxin-immunoreactive substance is present in the sera of third trimester pregnant women, but it does not contribute to the pathogenesis or prediction of preeclampsia.

Published
1993
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3. Conservative treatment of the ectopic pregnancy in the cesarean scar site: Case report [Sezaryen skar yerinde gelişen diş gebeligin konservatif tedavisi]

Author

Büyükkurt S., Aksungur E., Vardar M.A., Güzel A.B., Küçükgöz Güleç Ü., Kadayifçi O., and Çukurova Üniversitesi

Subjects
Methotrexate, Pregnancy, Uterine artery embolization, Uterine rupture, Ectopic, Curettage
Abstract

Cesarean scar pregnancy is a rare form of the ectopic pregnancy and its consequences may be fatal. Its treatment is based on the hysterectomy or conservative choices. Conservative modalities may be listed as surgical (low uterine segment excision with laparotomy or laparoscopy, hysteroscopy, curettage), medical [systemic or local use of methotrexate, local potassium chloride (KCI) injection] and minimally invasive interventions (selective uterine artery embolization). A cesarean scar pregnancy was tried to treat with low dose methotrexate regiment in a woman who had two cesareans previously. While this regiment was unsuccessful it was switched to the high dose methotrexate and uterine artery embolization. The bleeding during the destruction of the gestational sac was controlled with curettage and cervical balloon tamponade. Preservation of the uterus and the life of the woman are related to the early diagnosis and treatment. A combination of the many ways may be necessary in the treatment ofthe cesarean scar pregnancy. The collaboration of the ß-hCG levels as well as the progesteron levels and the presence of the cardiac activity may be more useful in the prediction of treatment success of the low dose methotrexate regiment. Copyright © 2010 by Türkiye Klinikleri.

Published
2010

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