1. Intravenous Iron Treatment in Pregnancy: Ferric Carboxymaltose for Correction of Iron Deficiency Anaemia
- Author
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Dilruba Zeba, Parvin Akter Khanam, Abul Khair, and Mansur Ahamed
- Subjects
Pregnancy ,medicine.medical_specialty ,Fetus ,business.industry ,Iron deficiency ,medicine.disease ,Gastroenterology ,Inherent risk ,Internal medicine ,medicine ,Ferric ,Prospective cohort study ,business ,Adverse effect ,medicine.drug ,Whole blood - Abstract
Iron deficiency is the most common nutritional deficiency state of women in childbearing age. Peri-partum iron deficiency anaemia (IDA) is associated with significant maternal, fetal and infant morbidity. An effective management is needed to prevent adverse outcomes. Current options for treatment are limited; these include oral iron supplements, which are usually ineffective and poorly tolerated, and whole blood transfusion, which carries an inherent risk, should be avoided during pregnancy. Intravenous ferric carboxymaltose is a new treatment option and it is better tolerated with a good result. The study was designed to assess the safety and efficacy of intravenous ferric carboxymaltose for correction of IDA in pregnant women in third trimester. It was a prospective study; 260 anaemic pregnant women received Injection ferric carboxymaltose, as a total dose of 500-1000 mg between 28 to 36 weeks of pregnancy. Safety was assessed by analyzing adverse drug reactions. Ferric carboxy maltose significantly increased Hb level (p
- Published
- 2017
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