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Xu, H.; Rui, X.; Wang, Z.; Qiu, Z.; Cai, L.; Zhang, Z., and Zhao, M., 2022. The effects of physical properties on the compression modulus of coastal fully-weathered red sandstone: Consolidation compressibility and the settlement calculation of foundation. Journal of Coastal Research, 38(4), 870–884. Coconut Creek (Florida), ISSN 0749-0208. The compressibility of rock and soil can be characterized by compression modulus, which is influenced by multiple physical properties, so it is difficult to be quickly and accurately measured on-site; thus, comprehensive exploration of their influence on the compression modulus is significant. In this paper, the physical properties of water content, fines content, and relative compaction, which can be easily measured on-site, were selected. Based on the orthogonal combination consolidation test, the variation of compression modulus of fully weathered red sandstone was investigated. Then, the relationship between compression modulus and the combination of physical properties was learned using the decision tree algorithm model for the first time, which can perform accurate and real-time prediction. The results showed that the cubic and quaternary polynomials can accurately represent the variation of compression modulus with a single physical property, and the model based on a 10-level decision tree algorithm can learn the coupling relationship between compression modulus and combination of physical properties to accurately calculate and predict the compression modulus. The algorithm model can be further applied to calculate the settlement of foundation in fully weathered red sandstone stratum with different water content during the precipitation process, which can effectively guide the engineering construction. This research provides a reference for the study of consolidation compressibility of fully weathered red sandstone and similar stratum, as well as the settlement calculation of foundation. [ABSTRACT FROM AUTHOR]