1. Lesions in chickens with spontaneous or experimental infectious hepato-myelopoietic disease (inclusion body hepatitis) in Germany.
- Author
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Hoffmann R, Wessling E, Dorn P, and Dangschat H
- Subjects
- Animals, Bone Marrow pathology, Bursa of Fabricius pathology, Cecum pathology, Disseminated Intravascular Coagulation pathology, Disseminated Intravascular Coagulation veterinary, Germany, West, Hepatitis, Animal transmission, Kidney pathology, Liver pathology, Myocardium pathology, Necrosis, Poultry Diseases transmission, Spleen pathology, Thymus Gland pathology, Chickens, Hepatitis, Animal pathology, Inclusion Bodies, Viral, Poultry Diseases pathology
- Abstract
A group of 83 two-to-eighteen-week-old chickens with acute infectious hepato-myelopoietic disease (a German form of inclusion-body-hepatitis) were observed to have the following histologic lesions: panmyelophthisis, small foci of liver necrosis, often with intranuclear inclusion bodies in hepatocytes (15 to 20% of chickens), involution-like atrophy of the bursa of Fabricius and thymus, loss of lymphatic tissue in spleen and cecal tonsils, and nonpurulent myocarditis. In 18 survivors 6 to 8 weeks after clinical signs of disease, nonpurulent myocarditis but normal lymphatic organs and bone marrow were present. A group of 75 chickens were infected after hatching with the field isolant "1942." Between the 3rd and 9th weeks postinoculation the same histologic changes-though mostly milder-were demonstrated. This syndrome differs somewhat from the syndrome described as inclusion body hepatitis in America and Europe.
- Published
- 1975