1. Virus-PEDOT nanowires for biosensing.
- Author
-
Arter JA, Taggart DK, McIntire TM, Penner RM, and Weiss GA
- Subjects
- Bacteriophage M13 chemistry, Microscopy, Atomic Force, Microscopy, Electron, Scanning, Spectroscopy, Fourier Transform Infrared, Biosensing Techniques, Bridged Bicyclo Compounds, Heterocyclic chemistry, Nanowires, Polymers chemistry
- Abstract
The separate fields of conducting polymer-based electrochemical sensors and virus-based molecular recognition offer numerous advantages for biosensing. Grafting M13 bacteriophage into an array of poly (3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses. The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition. The resultant arrays of virus-PEDOT nanowires enable real-time, reagent-free electrochemical biosensing of analytes in physiologically relevant buffers.
- Published
- 2010
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