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Your search keyword '"Zakharova ML"' showing total 2 results
Start Over Author "Zakharova ML" Topic plutonium
2 results on '"Zakharova ML"'

1. [Cytogenetic effects of alpha-irradiation due to incorporated 239Pu].

Author

Zakharova ML, Osobets SV, Uriadnitskaia TI, Sokhranich AL, and Muksinova KN

Subjects
Animals, Bone Marrow Cells ultrastructure, Male, Rats, Chromosome Aberrations, Plutonium toxicity
Abstract

Intravenous injection of plutonium dioxide with 1-2 microns particle sizes in amount of 92.5, 46.3 and 23.2 kBq/kg of body mass increased the yield of chromosome aberrations in bone marrow cells of rats by 3.7, 2.3 and 1.7 times, correspondingly, in comparison with the spontaneous level. The model of chromosome aberration dependence on dose of radionuclide was developed based on the experimental results.

Published
2002

2. [Frequency of structural chromosome aberrations in the hepatocytes of rats exposed to polymeric 239Pu].

Author

Zakharova ML, Uriadnitskaia TI, Sokhranich AL, Revina VS, and Nifatov AP

Subjects
Animals, Injections, Intravenous, Liver ultrastructure, Male, Polymers, Rats, Rats, Inbred Strains, Chromosome Aberrations, Liver radiation effects, Nitrates, Plutonium administration & dosage
Abstract

Intravenous injection of polymeric 239Pu(IV) nitrate (166.5, 55.5 and 18.5 kBq/kg body mass) to Wistar rats was shown to produce biphase changes in the frequency of hepatocyte chromosome aberrations. The increase in the structural damages to chromosomes at later times of observation was a pronounced function of radiation dose. The absence of such a dependence at early times was evidently due to the elimination of damaged liver parenchyma cells.

Published
1988

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