1. BFA effects are tissue and not just plant specific.
- Author
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Robinson DG, Langhans M, Saint-Jore-Dupas C, and Hawes C
- Subjects
- Golgi Apparatus metabolism, Golgi Apparatus ultrastructure, Hypocotyl drug effects, Hypocotyl metabolism, Hypocotyl ultrastructure, Microscopy, Electron, Transmission, Plant Leaves drug effects, Plant Leaves metabolism, Plant Leaves ultrastructure, Plants metabolism, Plants ultrastructure, Brefeldin A pharmacology, Golgi Apparatus drug effects, Plants drug effects
- Abstract
Brefeldin A (BFA) is one of the most popular drugs used by researchers for studies on secretion and endocytosis because it interferes with specific vesicle coat proteins via action on a guanine nucleotide exchange factor. Due to its range of morphological effects on the Golgi apparatus in a variety of plant tissues, we believe that there is more to the BFA response than the primary molecular targets so far identified.
- Published
- 2008
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