1. Circulating T-Regulatory Cells, Exercise and the Elite Adolescent Swimmer.
- Author
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Wilson, Lori D., Zaldivar, Frank P., Schwindt, Christina D., Wang-Rodriguez, Jessica, and Cooper, Dan M.
- Subjects
EXERCISE physiology ,LEUCOCYTOSIS ,ALLERGIES ,PHYSIOLOGICAL effects of swimming ,SWIMMERS' health ,ADOLESCENT health ,PHYSIOLOGY - Abstract
Brief high intensity exercise induces peripheral leukocytosis possibly leading to a higher incidence of allergic symptoms in athletes undergoing excessive training. We studied the exercise-induced alternation of circulating Tregs and FoxP3+ Tregs due to acute intense swim exercise in elite swimmers (n = 22, 12 males, age = 15.4 yrs). Twelve had prior or current rhinitis or asthma and 10 had no current or prior allergy or asthma. Circulating Tregs increased significantly (p < .001) following exercise (pre = 133 ± 11.2, post = 196 ± 17.6) as did FoxP3+ cells (pre = 44, post = 64 cells/μl). Increases in Tregs and FoxP3+ Tregs occurred to the same extent in both groups of adolescent swimmers. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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