1. Calibration of activity-related energy expenditure in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
- Author
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Robert G. McMurray, Lisa Sanchez-Johnsen, Mercedes R. Carnethon, Mark Stoutenberg, Ashley E. Moncrieft, Robert C. Kaplan, Charles E. Matthews, Yasmin Mossavar-Rahmani, William W. Wong, Daniela Sotres-Alvarez, Pamela A. Shaw, Kelly R. Evenson, Nancy F. Butte, Hengrui Sun, and Elva M. Arredondo
- Subjects
Adult ,Male ,Doubly labeled water ,Adolescent ,Calibration (statistics) ,Physical Therapy, Sports Therapy and Rehabilitation ,Indirect calorimetry ,Article ,Cohort Studies ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Measurement error ,Accelerometry ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Resting energy expenditure ,030212 general & internal medicine ,Exercise ,Aged ,Models, Statistical ,business.industry ,Calorimetry, Indirect ,030229 sport sciences ,Hispanic or Latino ,Middle Aged ,Hchs sol ,Energy expenditure ,Self-assessment ,Cohort ,Community health ,Calibration ,Female ,Self Report ,business ,Energy Metabolism ,Cohort study ,Demography - Abstract
Objectives Usual physical activity (PA) is a complex exposure and typical instruments to measure aspects of PA are subject to measurement error, from systematic biases and biological variability. This error can lead to biased estimates of associations between PA and health outcomes. We developed a calibrated physical activity measure that adjusts for measurement error in both self-reported and accelerometry measures of PA in adults from the US Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a community-based cohort study. Design Total energy expenditure (TEE) from doubly labeled water and resting energy expenditure (REE) from indirect calorimetry were measured in 445 men and women aged 18–74 years in 2010–2012, as part of the HCHS/SOL Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS). Measurements were repeated in a subset (N = 98) 6 months later. Method Calibration equations for usual activity-related energy expenditure (AEE = 0.90 × TEE-REE) were developed by regressing this objective biomarker on self-reported PA and sedentary behavior, Actical accelerometer PA, and other subject characteristics. Results Age, weight and height explained a significant amount of variation in AEE. Actical PA and wear-time were important predictors of AEE; whereas, self-reported PA was not independently associated with AEE. The final calibration equation explained fifty percent of variation in AEE. Conclusions The developed calibration equations can be used to obtain error-corrected associations between PA and health outcomes in HCHS/SOL. Our study represents a unique opportunity to understand the measurement characteristics of PA instruments in an under-studied Hispanic/Latino cohort.
- Published
- 2018