16 results on '"Witham, Miles D."'
Search Results
2. Validation of the AX3 triaxial accelerometer in older functionally impaired people
- Author
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Clarke, Clare L., Taylor, Judith, Crighton, Linda J., Goodbrand, James A., McMurdo, Marion E. T., and Witham, Miles D.
- Published
- 2017
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3. Increasing physical activity levels in care homes for older people: a quantitative scoping review of intervention studies to guide future research.
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Wylie, Gavin, Kroll, Thilo, Witham, Miles D., and Morris, Jacqui
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CINAHL database ,PSYCHOLOGY information storage & retrieval systems ,MEDICAL information storage & retrieval systems ,SYSTEMATIC reviews ,COGNITION ,NURSING care facilities ,PHYSICAL activity ,DECISION making ,DESCRIPTIVE statistics ,BODY movement ,RESEARCH funding ,LITERATURE reviews ,MANAGEMENT ,MEDLINE ,ELDER care ,HEALTH promotion ,AMED (Information retrieval system) - Abstract
Physical activity (PA) levels in older care home residents are low. This has detrimental effects on health. Little is known about the nature of interventions to increase physical activity in this population. A scoping review to: (1) identify and describe interventions to increase PA in older care home residents, and (2) describe the extent to which interventions address care home context, systemised by social–ecological models. We systematically searched databases for peer-reviewed intervention studies to increase PA in older people resident in care homes. Data were extracted using the template for intervention description and replication (TIDieR) and mapped against a social–ecological framework to locate the intervention focus. The 19 included studies consisted of interventions tested in randomised or quasi-experimental trial designs. Interventions consisted of single or multiple components and predominantly addressed individual resident level factors (such as muscle strength) rather than broader social and environmental aspects of context. Interventions were not all fully described. For most interventions a distinct theoretical foundation was not identified. Interventions were mostly delivered by health professionals and research staff external to care homes. Future interventions should address contextual care home factors and should be clearly described according to intervention description guidance. Physical activity holds promise as an effective means of improving health and function in older care home residents, but physical activity levels in this population are low. Several reasons beyond the individual resident but related to care home contextual factors may explain low PA in care homes To date, contextual factors influencing PA in care homes have been poorly addressed in interventions. Wider care home context (social, cultural, and environmental factors) must be considered in future interventions. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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4. Using the RT3 accelerometer to measure everyday activity in functionally impaired older people
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Sumukadas, Deepa, Laidlaw, Simon, and Witham, Miles D.
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- 2008
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5. Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities.
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Richardson, Sarah J, Carroll, Camille B, Close, Jacqueline, Gordon, Adam L, O'Brien, John, Quinn, Terence J, Rochester, Lynn, Sayer, Avan A, Shenkin, Susan D, van der Velde, Nathalie, Woo, Jean, and Witham, Miles D
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COGNITION ,HEALTH planning ,IMMUNIZATION ,MENTAL health ,PUBLIC health ,REHABILITATION ,RESEARCH ,SOCIAL support ,PHYSICAL activity ,SOCIAL distancing ,STAY-at-home orders ,COVID-19 pandemic ,OLD age - Abstract
Older people are disproportionately affected by the COVID-19 pandemic, which has had a profound impact on research as well as clinical service delivery. This commentary identifies key challenges and opportunities in continuing to conduct research with and for older people, both during and after the current pandemic. It shares opinions from responders to an international survey, a range of academic authors and opinions from specialist societies. Priorities in COVID-19 research include its specific presentation in older people, consequences for physical, cognitive and psychological health, treatments and vaccines, rehabilitation, supporting care homes more effectively, the impact of social distancing, lockdown policies and system reconfiguration to provide best health and social care for older people. COVID-19 research needs to be inclusive, particularly involving older people living with frailty, cognitive impairment or multimorbidity, and those living in care homes. Non-COVID-19 related research for older people remains of critical importance and must not be neglected in the rush to study the pandemic. Profound changes are required in the way that we design and deliver research for older people in a world where movement and face-to-face contact are restricted, but we also highlight new opportunities such as the ability to collaborate more widely and to design and deliver research efficiently at scale and speed. [ABSTRACT FROM AUTHOR]
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- 2020
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6. Association Between Objectively Measured Physical Activity and Opioid, Hypnotic, or Anticholinergic Medication Use in Older People: Data from the Physical Activity Cohort Scotland Study.
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Clarke, Clare L., Sniehotta, Falko F., Vadiveloo, Thenmalar, Donnan, Peter T., and Witham, Miles D.
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THERAPEUTIC use of narcotics ,PARASYMPATHOMIMETIC agents ,ACCELEROMETERS ,LONGITUDINAL method ,REGRESSION analysis ,INDEPENDENT living ,CROSS-sectional method ,PHYSICAL activity ,OLD age ,THERAPEUTICS - Abstract
Background: Centrally acting medications cause cognitive slowing and incoordination, which could reduce older people’s physical activity levels. This association has not been studied previously.Objectives: The aim of this study was to examine the association between opioid, hypnotic and anticholinergic medication, and objectively measured physical activity, in a cohort of older people.Methods: We used data from the Physical Activity Cohort Scotland, a representative cohort of community-dwelling older people aged 65 years and over who were assessed at baseline and again 2-3 years later. Objective physical activity was measured using Stayhealthy RT3 accelerometers over 7 days. Baseline medication use (opioid use, hypnotic use, modified Anticholinergic Risk Scale [mARS]) was obtained from linked, routinely collected community prescribing records. Cross-sectional and longitudinal associations between baseline medication use and both baseline activity and change in activity over time were analysed using unadjusted and adjusted linear regression models.Results: Overall, 310 participants were included in the analysis; mean age 77 years (standard deviation 7). No association was seen between baseline use of any medication class and baseline physical activity levels in unadjusted or adjusted models. For change in activity over time, there was no difference between users and non-users of hypnotics or opioids. Higher anticholinergic burden was associated with a steeper decline in activity over the follow-up period (mARS 0: − 7051 counts/24 h/year; mARS 1-2: − 15,942 counts/24 h/year; mARS ≥ 3: − 19,544 counts/24 h/year; p = 0.03) and this remained robust to multiple adjustments.Conclusion: Anticholinergic burden is associated with greater decline in objectively measured physical activity over time in older people, a finding not seen with hypnotic or opioid use. [ABSTRACT FROM AUTHOR]
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- 2018
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7. Factors associated with change in objectively measured physical activity in older people - data from the physical activity cohort Scotland study.
- Author
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Clarke, Clare L., Sniehotta, Falko F., Vadiveloo, Thenmalar, Argo, Ishbel S., Donnan, Peter T., McMurdo, Marion E. T., and Witham, Miles D.
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PHYSICAL fitness for older people ,COHORT analysis ,PHYSICAL activity measurement ,QUALITY of life ,ACCELEROMETERS ,PSYCHOLOGICAL aspects of aging ,GERIATRIC assessment ,AGING ,HEALTH status indicators ,HEALTH surveys ,LONGITUDINAL method ,MOTOR ability ,QUESTIONNAIRES ,RESEARCH funding ,ACCELEROMETRY ,PREDICTIVE tests ,INDEPENDENT living ,CROSS-sectional method - Abstract
Background: Cross-sectional relationships between physical activity and health have been explored extensively, but less is known about how physical activity changes with time in older people. The aim of this study was to assess baseline predictors of how objectively measured physical activity changes with time in older people.Methods: Longitudinal cohort study using data from the Physical Activity Cohort Scotland. A sample of community-dwelling older people aged 65 and over were recruited in 2009-2011, then followed up 2-3 years later. Physical activity was measured using Stayhealthy RT3 accelerometers over 7 days. Other data collected included baseline comorbidity, health-related quality of life (SF-36), extended Theory of Planned Behaviour Questionnaire and Social Capital Module of the General Household Survey. Associations between follow-up accelerometer counts and baseline predictors were analysed using a series of linear regression models, adjusting for baseline activity levels and follow-up time.Results: Follow up data were available for 339 of the original 584 participants. The mean age was 77 years, 185 (55%) were female and mean follow up time was 26 months. Mean activity counts fell by between 2% per year (age < =80, deprivation decile 5-10) and 12% per year (age > 80, deprivation decile 5-10) from baseline values. In univariate analysis age, sex, deprivation decile, most SF-36 domains, most measures of social connectedness, most measures from the extended Theory of Planned Behaviour, hypertension, diabetes mellitus, chronic pain and depression score were significantly associated with adjusted activity counts at follow-up. In multivariate regression age, satisfactory friend network, SF-36 physical function score, and the presence of diabetes mellitus were independent predictors of activity counts at follow up after adjustment for baseline count and duration of follow up.Conclusions: Health status and social connectedness, but not extended Theory of Planned Behaviour measures, independently predicted changes in physical activity in community dwelling older people. [ABSTRACT FROM AUTHOR]- Published
- 2017
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8. The emergence of sarcopenia as an important entity in older people.
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Offord, Natalie J. and Witham, Miles D.
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ACCIDENTAL fall prevention , *GRIP strength , *INFLAMMATION , *LEUCINE , *AGE distribution , *CELL physiology , *DIAGNOSIS , *DIET , *CLINICAL drug trials , *EXERCISE , *FRAIL elderly , *GAIT in humans , *GERIATRICS , *HORMONES , *HOSPITAL care , *LENGTH of stay in hospitals , *MOVEMENT disorders , *MUSCLE strength , *OXIDATIVE stress , *PHYSICAL activity , *ALLOPURINOL , *MYOSTATIN , *SARCOPENIA , *PHOTON absorptiometry , *RESISTANCE training , *THERAPEUTICS , *DISEASE risk factors - Abstract
Sarcopenia refers to the loss of muscle mass and strength seen with advancing age. The pathophysiology is multifactorial, with loss of muscle satellite cells, changes in hormonal systems, chronic inflammation, oxidative stress and anabolic resistance to protein utilisation all implicated. Older age, female sex and immobility are important risk factors. Sarcopenia is clinically important as it is a major risk factor for physical frailty, falls, prolonged hospitalisation, dependency and earlier death. Diagnosis requires evidence of reduced muscle mass measured by handgrip strength or walk speed, together with evidence of low muscle mass, measured by one of a variety of techniques such as bioimpedance analysis or dual X-ray absorptiometry. Resistance training is the only intervention of proven efficacy to treat sarcopenia, but a range of nutritional and pharmacological interventions are under test, including myostatin inhibitors, leucine and protein supplementation, angiotensin-converting enzyme inhibitors and allopurinol. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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9. The Effects of Medication on Activity and Rehabilitation of Older People -- Opportunities and Risks.
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Clarke, Clare L. and Witham, Miles D.
- Abstract
Multiple medication use, or polypharmacy, is common in people undergoing rehabilitation. Polypharmacy is also common in older people, where it has the potential to impact on habitual physical activity. Despite this, the interactions between medication, disease, activity, and rehabilitation outcomes are insufficiently researched. In this review, we consider common classes of medications that can affect physical activity levels and outcomes of rehabilitation. We consider medications that improve disease processes and improve limiting symptoms (eg, breathlessness in heart failure and lung disease, pain in arthritis), unwanted side effects of medications (eg, central slowing caused by opioids and hypnotics), and also medication classes that might have the ability to improve activity and rehabilitation outcomes via beneficial effects on neuromuscular function (eg, angiotensin-converting enzyme inhibitors). We conclude by giving practical advice on how to review and optimise medication use to support habitual physical activity and ensure the best results from rehabilitation. [ABSTRACT FROM AUTHOR]
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- 2017
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10. The role of perceived barriers and objectively measured physical activity in adults aged 65-100.
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GELLERT, PAUL, WITHAM, MILES D., CROMBIE, IAIN K., DONNAN, PETER T., MCMURDO, MARION E. T., and SNIEHOTTA, FALKO F.
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GERIATRIC assessment , *STATISTICAL correlation , *FACTOR analysis , *QUESTIONNAIRES , *RESEARCH funding , *MULTIPLE regression analysis , *ACCELEROMETRY , *INDEPENDENT living , *PLANNED behavior theory , *PHYSICAL activity , *DESCRIPTIVE statistics - Abstract
Objective: to test the predictive utility of perceived barriers to objectively measured physical activity levels in a stratified sample of older adults when accounting for social-cognitive determinants proposed by the Theory of Planned Behaviour (TPB), and economic and demographic factors. Methods: data were analysed from the Physical Activity Cohort Scotland survey, a representative and stratified (65-80 and 80+ years; deprived and affluent) sample of 584 community-dwelling older people, resident in Tayside, Scotland. Physical activity was measured objectively by accelerometry. Results: perceived barriers clustered around the areas of poor health, lack of interest, lack of safety and lack of access. Perceived poor health and lack of interest, but not lack of access or concerns about personal safety, predicted physical activity after controlling for demographic, economic and TPB variables. Discussion: perceived person-related barriers (poor health and lack of interest) seem to be more strongly associated with physical activity levels than perceived environmental barriers (safety and access) in a large sample of older adults. Perceived barriers are modifiable and may be a target for future interventions. [ABSTRACT FROM AUTHOR]
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- 2015
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11. Association of Day Length and Weather Conditions with Physical Activity Levels in Older Community Dwelling People.
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Witham, Miles D., Donnan, Peter T., Vadiveloo, Thenmalar, Sniehotta, Falko F., Crombie, Iain K., Feng, Zhiqiang, and McMurdo, Marion E. T.
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PHYSICAL activity , *OLDER people , *ACCELEROMETRY , *QUESTIONNAIRES , *SOCIAL epidemiology , *POPULATION biology - Abstract
Background: Weather is a potentially important determinant of physical activity. Little work has been done examining the relationship between weather and physical activity, and potential modifiers of any relationship in older people. We therefore examined the relationship between weather and physical activity in a cohort of older community-dwelling people. Methods: We analysed prospectively collected cross-sectional activity data from community-dwelling people aged 65 and over in the Physical Activity Cohort Scotland. We correlated seven day triaxial accelerometry data with daily weather data (temperature, day length, sunshine, snow, rain), and a series of potential effect modifiers were tested in mixed models: environmental variables (urban vs rural dwelling, percentage of green space), psychological variables (anxiety, depression, perceived behavioural control), social variables (number of close contacts) and health status measured using the SF-36 questionnaire. Results: 547 participants, mean age 78.5 years, were included in this analysis. Higher minimum daily temperature and longer day length were associated with higher activity levels; these associations remained robust to adjustment for other significant associates of activity: age, perceived behavioural control, number of social contacts and physical function. Of the potential effect modifier variables, only urban vs rural dwelling and the SF-36 measure of social functioning enhanced the association between day length and activity; no variable modified the association between minimum temperature and activity. Conclusions: In older community dwelling people, minimum temperature and day length were associated with objectively measured activity. There was little evidence for moderation of these associations through potentially modifiable health, environmental, social or psychological variables. [ABSTRACT FROM AUTHOR]
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- 2014
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12. Psychological theory in an interdisciplinary context: psychological, demographic, health-related, social, and environmental correlates of physical activity in a representative cohort of community-dwelling older adults.
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Sniehotta, Falko F., Gellert, Paul, Witham, Miles D., Donnan, Peter T., Crombie, Iain K., and McMurdo, Marion E. T.
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ACCELEROMETERS ,HEALTH surveys ,INTERDISCIPLINARY research ,PSYCHOLOGY ,QUESTIONNAIRES ,RESEARCH funding ,STATISTICAL sampling ,THEORY ,INDEPENDENT living ,CROSS-sectional method ,PHYSICAL activity ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background: Physical activity (PA) in older adults is influenced by a range of environmental, demographic, health-related, social, and psychological variables. Social cognitive psychological models assume that all influences on behaviour operate indirectly through the models constructs, i.e., via intention and self-efficacy. We evaluated direct, indirect, and moderating relationships of a broad range of external variables with physical activity levels alongside intention and self-efficacy. Methods: We performed a cross-sectional survey of a representative and stratified (65-80 and 80+ years; deprived and affluent) sample of 584 community-dwelling people, resident in Scotland. Objectively measured physical activity and questionnaire data were collected. Results: Self-efficacy showed unique relationships with physical activity, controlling for demographic, mental health, social, environmental, and weather variables separately, but the relationship was not significant when controlling for physical health. Overall, results indicating support for a mediation hypothesis, intention and self-efficacy statistically mediate the relationship of most domain variables with physical activity. Moderation analyses show that the relationship between social cognitions and physical activity was stronger for individuals with better physical health and lower levels of socio-economic deprivation. Conclusions: Social cognitive variables reflect a range of known environmental, demographic, health-related and social correlates of physical activity, they mediate the relationships of those correlates with physical activity and account for additional variance in physical activity when external correlates are controlled for, except for the physical health domain. The finding that the social cognition-physical activity relationship is higher for participants with better health and higher levels of affluence raises issues for the applicability of social cognitive models to the most disadvantaged older people. [ABSTRACT FROM AUTHOR]
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- 2013
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13. A comparison of the Endurance Shuttle Walk test and the Six Minute Walk test for assessment of exercise capacity in older people.
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Witham, Miles D., Sugden, Jacqui A., Sumukadas, Deepa, Dryburgh, Moira, and Mcmurdo, Marion E. T.
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CAFFEINE ,CONFIDENCE intervals ,STATISTICAL correlation ,CROSSOVER trials ,EXERCISE ,HIGH performance liquid chromatography ,RELIABILITY (Personality trait) ,RESEARCH funding ,STATISTICAL sampling ,STATISTICS ,WALKING ,INTER-observer reliability ,RESEARCH methodology evaluation ,PHYSICAL activity ,DATA analysis software ,DESCRIPTIVE statistics ,OLD age - Abstract
Background and aims: The six minute walk test is widely used to measure aerobic exercise capacity in older people, but lack responsiveness to change. We aimed to compare the reliability, responsiveness and completion rates of the six minute walk with a new test of aerobic exercise capacity - the endurance shuttle walk test. Methods: Two groups were studied: 18 patients from a Medicine for the Elderly Day Hospital (study 1) receiving physiotherapy, and 15 community dwelling older people (study 2) receiving caffeine or placebo in a crossover study, followed by a weekly exercise programme. Six minute walk test and endurance shuttle walk test were performed at baseline and after interventions. Intraclass correlation coefficients were calculated for reliability, and Cohen's effect sizes were calculated to characterize responsiveness. Results: 6/18 of patients in study 1 completed the baseline shuttle walk successfully. For those completing baseline and week one shuttle walk, similar intraclass correlation coefficients were seen (shuttle walk 0.97; six minute walk 0.90). In study 2, all attendees completed baseline and follow-up shuttle walk. 7/15 managed the maximum shuttle walk time at baseline. Effect sizes for caffeine intervention (0.29 for six minute walk, 0.01 for shuttle walk) and for exercise intervention (0.15 for six minute walk, 0.24 for shuttle walk) were similarly low for both tests. Conclusion: The endurance shuttle walk is no more responsive to change than the six minute walk in older people, is limited by ceiling effects, and cannot be performed successfully by very frail older people. [ABSTRACT FROM AUTHOR]
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- 2012
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14. Social, Environmental and Psychological Factors Associated with Objective Physical Activity Levels in the Over 65s.
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McMurdo, Marion E. T., Argo, Ishbel, Crombie, Iain K., Zhiqiang Feng, Sniehotta, Falko F., Vadiveloo, Thenmalar, Witham, Miles D., and Donnan, Peter T.
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PHYSICAL activity ,SOCIAL factors ,PSYCHOLOGICAL factors ,ACCELEROMETERS ,CROSS-sectional method - Abstract
Objective: To assess physical activity levels objectively using accelerometers in community dwelling over 65 s and to examine associations with health, social, environmental and psychological factors. Design: Cross sectional survey. Setting: 17 general practices in Scotland, United Kingdom. Participants: Random sampling of over 65 s registered with the practices in four strata young-old (65-80 years), old-old (over 80 years), more affluent and less affluent groups. Main Outcome Measures: Accelerometry counts of activity per day. Associations between activity and Theory of Planned Behaviour variables, the physical environment, health, wellbeing and demographic variables were examined with multiple regression analysis and multilevel modelling. Results: 547 older people (mean (SD) age 79(8) years, 54% female) were analysed representing 94% of those surveyed. Accelerometry counts were highest in the affluent younger group, followed by the deprived younger group, with lowest levels in the deprived over 80 s group. Multiple regression analysis showed that lower age, higher perceived behavioural control, the physical function subscale of SF-36, and having someone nearby to turn to were all independently associated with higher physical activity levels (R² = 0.32). In addition, hours of sunshine were independently significantly associated with greater physical activity in a multilevel model. Conclusions: Other than age and hours of sunlight, the variables identified are modifiable, and provide a strong basis for the future development of novel multidimensional interventions aimed at increasing activity participation in later life. [ABSTRACT FROM AUTHOR]
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- 2012
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15. Falls research: stumbling or striding?
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CLARKE, CLARE L., MCMURDO, MARION E. T., and WITHAM, MILES D.
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ACCIDENTAL fall prevention ,ELDER care ,POSTURAL balance ,MUSCLE strength ,RESEARCH ,PHYSICAL activity - Abstract
The article reflects on the several interventions on how to reduce the incident of falls in older people. It states that falls have been characterized as a major source of morbidity in older people that often lead them to injury, hospitalization and even death. It points out the efficacy of balance and strength training for the lower limbs to reduce the incident of falls. The challenges on the implementation of various interventions are also emphasized.
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- 2015
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16. Dog ownership and physical activity in later life: A cross-sectional observational study.
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Feng, Zhiqiang, Dibben, Chris, Witham, Miles D., Donnan, Peter T., Vadiveloo, Thenmalar, Sniehotta, Falko, Crombie, Iain K., and McMurdo, Marion E.T.
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PSYCHOLOGICAL ownership , *PHYSICAL activity , *CROSS-sectional method , *SCIENTIFIC observation , *DOG adoption - Abstract
Objective To examine whether dog ownership amongst community dwelling older adults (≥ 65years) is associated with objectively measured physical activity (PA). Methods We used data from the Physical Activity Cohort Scotland (PACS) which consists of 547 people aged 65 and over, resident in the community in Tayside, Scotland. The data was collected in 2009-2011. We assessed whether dog ownership is associated with objectively measured physical activity (accelerometry counts). Results The physical activity (PA) counts of 547 older people (mean age 79 (standard deviation (SD) 8years, 54% female) were analysed. Linear mixed models showed that dog ownership was positively related to higher PA levels. This positive relationship remained after controlling for a large number of individual and contextual variables, including attitude towards exercise, physical activity intention and history of physical activity. Dog owners were found to be 12% more active (21,875 counts, 95% Confidence Interval (CI): 2810 to 40,939, p<0.05) than non-dog owners. Conclusion Dog ownership is associated with physical activity in later life. Interventions to increase activity amongst older people might usefully attempt to replicate elements of the dog ownership experience. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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