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Your search keyword '"Miyazawa, Kazuki"' showing total 4 results
Start Over Author "Miyazawa, Kazuki" Topic photocatalysis
4 results on '"Miyazawa, Kazuki"'

1. Alkyl- and aryl-thioalkylation of olefins with organotrifluoroborates by photoredox catalysis

Author

LI, YanJie, Li, Yanjie, Miyazawa, Kazuki, Koike, Takashi, and AKITA, MUNETAKA

Subjects
Reaction conditions, chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Aryl, Radical, Organic Chemistry, Visible light irradiation, Pyridine, Photocatalysis, Photoredox catalysis, Photochemistry, Alkyl
Abstract

A facile and environmentally benign protocol for alkyl- and aryl-thioalkylation of olefins has been developed. Photoredox catalysis with an Ir photocatalyst, [Ir(dF(CF3)ppy)2(bpy)](PF6) (dF(CF3)ppy: 5-trifluoromethyl-2-(2,4-difluorophenyl)pyridine, bpy: 2,2′-bipyridine), induces efficient oxidation of a variety of alkyl- and aryl-thioalkyltrifluoroborates under visible light irradiation at room temperature, leading to the generation of α-thioalkyl radicals via deboronation. The generated α-thioalkyl radicals smoothly react with electron-deficient olefins to afford addition products in good yields. The present photocatalytic method provides us with simple and new access to a range of alkylsulphides under mild reaction conditions.

Published
2015

2. Aminohydroxylation of olefins with iminopyridinium ylides by dual Ir photocatalysis and Sc(OTf)3 catalysis.

Author

Miyazawa, Kazuki, Koike, Takashi, and Akita, Munetaka

Subjects
*HYDROXYLATION, *ALKENES, *PYRIDINIUM compounds, *PHOTOCATALYSIS, *SCANDIUM catalysts
Abstract

We have developed a new strategy for catalytic aminohydroxylation of olefins with an N -protected iminopyridinium ylide as the amine source. Iminopyridinium ylides N -protected with TFAc (trifluoroacetyl), Boc ( tert -butoxycarbonyl), Troc (2,2,2-trichloroethoxycarbonyl), and Alloc (allyloxycarbonyl) groups serve as N -centered radical precursors when combined with fac -[Ir(ppy) 3 ] photocatalysis and Sc(OTf) 3 catalysis. The dual Ir photoredox/Sc(OTf) 3 catalysis proves to be effective for aminohydroxylation of olefins under mild reaction conditions to provide 2-aminoalcohol derivatives bearing a primary amino group. [ABSTRACT FROM AUTHOR]

Published
2016
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3. Hydroaminomethylation of Olefins with Aminomethyltrifluoroborate by Photoredox Catalysis.

Author

Miyazawa, Kazuki, Koike, Takashi, and Akita, Munetaka

Subjects
*ALKENES, *AMINO acids, *AMINOBUTYRIC acid, *AMINO acid neurotransmitters, *BACLOFEN
Abstract

A photocatalytic hydroaminomethylation of olefins with N-protected aminomethyltrifluoroborates has been developed. This methodology provides a new strategy for the introduction of a primary aminomethyl group onto electron-deficient CC bonds. This reaction constitutes a facile entry into synthetically useful γ-aminobutyric acid (GABA) derivatives such as baclofen. [ABSTRACT FROM AUTHOR]

Published
2014
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4. ChemInform Abstract: Regiospecific Intermolecular Aminohydroxylation of Olefins by Photoredox Catalysis.

Author

Miyazawa, Kazuki, Koike, Takashi, and Akita, Munetaka

Subjects
*HYDROXYLATION, *ALKENES, *AMINO compounds, *OXIDATION-reduction reaction, *PHOTOCATALYSIS, *PYRIDINIUM compounds
Abstract

The present photocatalytic system enables regiospecific intermolecular three-component aminohydroxylation of olefins bearing a wide variety of functionalities. [ABSTRACT FROM AUTHOR]

Published
2016
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