1. The first diagnosis of Severe Fever with Thrombocytopenia Syndrome caused by tick-borne Severe Fever with Thrombocytopenia Syndrome virus in Chongqing, China: A case report and literature review.
- Author
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Hu X, Wu W, Zhi S, Xu W, Zhang Y, Li L, Tao Y, Duan G, Liao C, Wang L, Li L, Li Z, and Li W
- Subjects
- Humans, Female, Aged, China, High-Throughput Nucleotide Sequencing, Tick Bites complications, Tick-Borne Diseases diagnosis, Tick-Borne Diseases virology, Tick-Borne Diseases drug therapy, Antiviral Agents therapeutic use, Phlebovirus genetics, Phlebovirus isolation & purification, Severe Fever with Thrombocytopenia Syndrome diagnosis, Severe Fever with Thrombocytopenia Syndrome drug therapy
- Abstract
Background: Severe Fever with Thrombocytopenia Syndrome (SFTS) is a tick-borne disease caused by the SFTS virus (SFTSV) which has the potential to become a pandemic and is currently a major public health concern., Case Presentation: We present the case of a 74-year-old female from an urban area of Chongqing, with leukocytopenia, thrombocytopenia, organ function, inflammatory, blood coagulation, and immune abnormalities. SFTSV infection was confirmed through molecular detection and metagenomic next-generation sequencing (mNGS) analysis, indicating a diagnosis of SFTS due to the patient's history of tick bites. The patient received symptomatic and supportive therapy, including antibiotics, antiviral treatment, and antifungal therapy, and finally discharged from the hospital on day 18., Conclusions: This study highlights the need for increased awareness, early diagnosis, and prompt treatment for tick-borne SFTS. It also provides a comprehensive understanding of the disease's characteristics, pathogenesis, detection methods, and available treatments., Competing Interests: Declaration of competing interest The authors declare that they have no competing interests., (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Published
- 2024
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