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Start Over Author "Çetintaş, Yunus" Topic phenolics
3 results on '"Çetintaş, Yunus"'

1. GREEN SYNTHESIS, ANTIMICROBIAL AND ANTICANCER ACTIVITIES OF AgNPs PREPARED FROM THE LEAF EXTRACT OF Eucalyptus camaldulensis.

Author

ÇETİNTAŞ, Yunus, NADEEM, Said, SAKALLI ÇETİN, Esin, ELİUZ ERDOĞAN, Elif, and ÖZLER, Mehmet Ali

Subjects
EUCALYPTUS camaldulensis, MANNICH bases, SURFACE plasmon resonance, GALLIC acid, SILVER nanoparticles, ENVIRONMENTAL reporting, CANDIDA albicans
Abstract

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Published
2020
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2. GREEN SYNTHESIS, ANTIMICROBIAL AND ANTICANCER ACTIVITIES OF AgNPs PREPARED FROM THE LEAF EXTRACT OF Eucalyptus camaldulensis

Author

Yunus Çetintaş, Mehmet Ali Özler, Esin Sakalli, Said Nadeem, Elif Ayşe Erdoğan Eliuz, MÜ, Ula Ali Koçman Meslek Yüksekokulu, Gıda İşleme Bölümü, Çetintaş, Yunus, Sakallı Çetin, Esin, and Eliuz Erdoğan, Elif

Subjects
Chemistry, Silver nanoparticle, Mühendislik, Energy Engineering and Power Technology, Antimicrobial, Green synthesis, Horticulture, Engineering, Anticancer, Fuel Technology, Eucalyptus camaldulensis, Antimicrobial,anticancer,Eucalyptus camaldulensis,phenolics,silver nanoparticle,green synthesis, Phenolics
Abstract

Herein we report the green synthesis of silver nanoparticles (EcAgNPs) from water fraction (Ecs), obtained from methanol extract of Eucalyptus camaldulensis at room conditions. UV-vis, HR-TEM and SEM-EDS devices were used to characterize the EcAgNPs. The UV-visible spectrum of EcAgNPs showed surface plasmon resonance peak at 420 nm. HR-TEM images showed that the EcAgNPs were spherical with a diameter in the range 3.7-29.6 nm. Ag+ ions were reduced to Ago by phytochemicals in the without adding external reducing agent. The presence of biomolecules in the Ecs was investigated by UPLC-MS/MS that detected gallic acid (20.26±0.10 ppb) and quercetin (12.4±0.08 ppb) as major constituents. The antimicrobial activities of Ecs and synthesized EcAgNPs were tested on Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus strains and Candida albicans yeast. Ecs exhibited antimicrobial activity as MIC between 16.2 and 129.3 mg mL-1 while EcAgNP showed MIC between 6.31 and 14.65 μgmL-1. The cytotoxicity of both Ecs and EcAgNPs on A549, HT29 and MDA-MB-231 cancer cell lines was tested by MTT. EcAgNPs showed more significant anticancer activity on MDA-MB-231, HT29 and A549 cancer cell lines (8.10±0.01, 5.08±0.01 and 18.58±0.03 μg mL-1) than Ecs (219.70±0.73, 916.24±0.67, 999.30±1.86 μg mL-1) and it should be investigated for use in various therapeutics. Eucalyptus camaldulensis'in oda koşullarındaki metanol ekstresi aracılı su fraksiyonu (Ecs) kullanılarak gümüş nanopartiküllerin (EcAgNP'ler) yeşil sentezini sunuyoruz. EcAgNP'leri karakterize etmek için UV-vis, HR-TEM ve SEM-EDS cihazları kullanıldı. EcAgNP'lerin UV-visible spektrumu 420 nm'de yüzey plazmon rezonans pikini gösterdi. HR-TEM görüntüleri, EcAgNP'lerin çapının 3.7-29.6 nm aralığında küresel olduğunu gösterdi. Ag+ iyonları, başka indirgeyici madde eklenmeden Ecs’deki fitokimyasallar tarafından Ago'a indirildi. Ecs içindeki biyomoleküllerin varlığı, gallik asit (20.26±0.10 ppb) ve kuarsetin (12.4±0.08 ppb) major bileşenler olarak tespit edildiği UPLC-MS/MS ile araştırıldı. Ecs ve sentezlenmiş EcAgNP'lerin antimikrobiyal aktiviteleri, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus suşları ve Candida albicans mayası üzerinde test edildi. Ecs, MIC olarak 16.2 ve 129.3 mg mL-1 arasında antimikrobiyal aktivite sergilerken, EcAgNP, 6.31 ve 14.65 μg mL-1 arasında MIC gösterdi. A549, HT29 ve MDA-MB-231 kanser hücre hatlarında Ecs ve EcAgNP'lerin sitotoksisitesi, MTT ile test edildi. EcAgNPs MDA-MB-231, HT29 ve A549 kanser hücre hatları üzerinde (8.10±0.01, 5.08±0.01 and 18.58±0.03 μg mL-1) Ecs'ye (219.70±0.73, 916.24±0.67, 999.30±1.86 μg mL-1) göre daha dikkate değer antikanser aktivite sergilemiştir ve çeşitli terapötiklerde kullanımı için araştırılmalıdır.

Published
2020

3. Phenolic Compounds of Pinus brutia Ten.: Chemical Investigation and Quantitative Analysis Using an Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Source.

Author

Kıvrak, İbrahim, Kıvrak, Şeyda, Harmandar, Mansur, and Çetintaş, Yunus

Subjects
*PHYSIOLOGICAL effects of phenols, *PINUS brutia, *QUANTITATIVE chemical analysis, *HIGH performance liquid chromatography, *TANDEM mass spectrometry, *ELECTROSPRAY ionization mass spectrometry, *BARK, *HYDRATES
Abstract

In this study, phenolic content of Pinus brutia's bark was examined using an ultra-performance liquid chromatography tandem mass spectrometry with electrospray ionization source (UPLC-ESI-MS/MS) working in multiple reaction monitoring mode. Ultrasonic extraction method with 50% ethanol solution was used for the extraction of bark. The bark of Pinus brutia consisted of 15 compounds: gallic acid, gentisic acid, protocatechuic acid, 4-hydroxy benzoic acid, catechin hydrate, vanillic acid, caffeic acid, vanillin, p-coumaric acid, ferulic acid, myricetin, resveratrol, luteolin, naringenin, kaempferol. Major compound detected was catechin hydrate (28.305 mg 100 g-1 extract). The phenolic compounds of Pinus brutia extract and pycnogenol were compared, and it is shown that both of them consisted of considerable amount of phenolic compounds. [ABSTRACT FROM AUTHOR]

Published
2013

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