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The possibility of isolating total esters (ferulen) from Ferula tenuisecta roots has been studied. Optimum conditions for extraction of ferulen are established. The results are used to develop a processing scheme for ferulen isolation. Quantitative determination methods for ferulen are proposed.

The optimal regime of cinaroside extraction from the aerial part of Ferula varia has been found. Aprocessing scheme for obtaining cinaroside has been developed on the basis of these data. Two samples of cinaroside (obtained by the laboratory and semi-industrial methods) are comparable to the well-known medicinal preparation lespenephryl with respect to hypoazotemic action. This fact indicates that Ferula varia is a valuable source of cinaroside. A technology has been developed for producing a new medicinal form of cinaroside in 0.05 g tablets.

The optimal regime for extraction of the total flavonoid fraction from the roots of Pseudosophora alopecuroides has been found and the corresponding technological scheme for the isolation of flavonoids from this medicinal plant has been developed. Acomparative pharmacological investigation showed that both the total flavonoid extract obtained using a semicommercial apparatus according to the proposed technology and a laboratory preparation are comparable in activity with the well-known drug tanacechol based on common tansy flowers. This result shows that Pseudosophora alopecuroides offers an important source of biologically active flavonoids possessing hepatoprotector and biligenic activity. The annular natural resource of roots of this medicinal plant has been evaluated. The qualitative composition of the flavonoids and their total content in various extracts have been compared.