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Your search keyword '"Kilin, M."' showing total 2 results
Start Over Author "Kilin, M." Topic pharmacology
2 results on '"Kilin, M."'

1. Nitrazepam Synthesized by Amination of 2-(2-Chloroacetamido)-5-nitrobenzophenone with Hexamethylenetetramine.

Author

Anikeev, V. N., Petrunin, A. I., Kilin, M. T., and Guss, F. V.

Subjects
*AMINATION, *BENZODIAZEPINES, *REACTION mechanisms (Chemistry), *PHARMACEUTICAL chemistry, *PHARMACOLOGY, *ANALYTICAL chemistry
Abstract

Studies the nitrazepam synthesized by amination of 2-(2-chloroacetamido)-5-nitrobenzophenone with hexamethylenetetramine. Reaction mechanism of hexamine; Effect of the molar ratio of ammonium chloride to 2-(2-chloroacetamido)-5-benzophenone on the yield of nitrazepam; Effect of the moral ratios of heximine.

Published
2004
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2. Commercial synthesis of nitrazepam via interaction of 2-chloro-5-nitrobenzophenone with ethylenediamine.

Author

Anikeev, V., Petrunin, A., Zhukov, Y., Kilin, M., and Guss, F.

Subjects
*BIOSYNTHESIS, *PHARMACOLOGY, *METHODOLOGY, *OXIDATION, *AMINES, *DRUGS
Abstract

A commercial synthesis of nitrazepam has been developed based on the interaction of 2-chloro-5-nitrobenzophenone with ethylenediamine and the subsequent oxidation of intermediate benzodiazepine to benzodiazepinone. The proposed method has been successfully implemented in practice. [ABSTRACT FROM AUTHOR]

Published
2005
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