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7 results on '"Buneman,O Peter"'

1. The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets.

Author

Alexander SPH, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Buneman OP, Faccenda E, Harding SD, Spedding M, Cidlowski JA, Fabbro D, Davenport AP, Striessnig J, Davies JA, Ahlers-Dannen KE, Alqinyah M, Arumugam TV, Bodle C, Dagner JB, Chakravarti B, Choudhuri SP, Druey KM, Fisher RA, Gerber KJ, Hepler JR, Hooks SB, Kantheti HS, Karaj B, Layeghi-Ghalehsoukhteh S, Lee JK, Luo Z, Martemyanov K, Mascarenhas LD, McNabb H, Montañez-Miranda C, Ogujiofor O, Phan H, Roman DL, Shaw V, Sjogren B, Sobey C, Spicer MM, Squires KE, Sutton L, Wendimu M, Wilkie T, Xie K, Zhang Q, and Zolghadri Y

Subjects
Humans, Databases, Factual, Ion Channels, Ligands, Receptors, Cytoplasmic and Nuclear, Databases, Pharmaceutical, Pharmacology
Abstract

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16176. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are six areas of focus: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate., (© 2023 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.)

Published
2023
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2. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets.

Author

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA, Ahlers-Dannen KE, Alqinyah M, Arumugam TV, Bodle C, Dagner JB, Chakravarti B, Choudhuri SP, Druey KM, Fisher RA, Gerber KJ, Hepler JR, Hooks SB, Kantheti HS, Karaj B, Layeghi-Ghalehsoukhteh S, Lee JK, Luo Z, Martemyanov K, Mascarenhas LD, McNabb H, Montañez-Miranda C, Ogujiofor O, Phan H, Roman DL, Shaw V, Sjogren B, Sobey C, Spicer MM, Squires KE, Sutton L, Wendimu M, Wilkie T, Xie K, Zhang Q, and Zolghadri Y

Subjects
Humans, Ion Channels, Ligands, Protein Transport, Receptors, Cytoplasmic and Nuclear, Databases, Pharmaceutical, Pharmacology
Abstract

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15537. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are six areas of focus: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate., (© 2021 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.)

Published
2021
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3. The Concise Guide to PHARMACOLOGY 2015/16: Overview.

Author

Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Buneman OP, Catterall WA, Cidlowski JA, Davenport AP, Fabbro D, Fan G, McGrath JC, Spedding M, and Davies JA

Subjects
Animals, Humans, Databases, Pharmaceutical, Pharmacology
Abstract

The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates., (© 2015 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.)

Published
2015
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4. IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels

Author

Harmar, Anthony J., Hills, Rebecca A., Rosser, Edward M., Jones, Martin, Buneman, O. Peter, Dunbar, Donald R., Greenhill, Stuart D., Hale, Valerie A., Sharman, Joanna L., Bonner, Tom I., Catterall, William A., Davenport, Anthony P., Delagrange, Philippe, Dollery, Colin T., Foord, Steven M., Gutman, George A., Laudet, Vincent, Neubig, Richard R., Ohlstein, Eliot H., Olsen, Richard W., Peters, John, Pin, Jean-Philippe, Ruffolo, Robert R., Searls, David B., Wright, Mathew W., and Spedding, Michael

Subjects
international union, sequence database, genome database, nomenclature, pharmacology, information, gene, update, knowledgebase, subunits
Abstract

The IUPHAR database (IUPHAR-DB) integrates peer-reviewed pharmacological, chemical, genetic, functional and anatomical information on the 354 nonsensory G protein-coupled receptors (GPCRs), 71 ligand-gated ion channel subunits and 141 voltage-gated-like ion channel subunits encoded by the human, rat and mouse genomes. These genes represent the targets of approximately one-third of currently approved drugs and are a major focus of drug discovery and development programs in the pharmaceutical industry. IUPHAR-DB provides a comprehensive description of the genes and their functions, with information on protein structure and interactions, ligands, expression patterns, signaling mechanisms, functional assays and biologically important receptor variants (e.g. single nucleotide polymorphisms and splice variants). In addition, the phenotypes resulting from altered gene expression (e.g. in genetically altered animals or in human genetic disorders) are described. The content of the database is peer reviewed by members of the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR); the data are provided through manual curation of the primary literature by a network of over 60 subcommittees of NC-IUPHAR. Links to other bioinformatics resources, such as NCBI, Uniprot, HGNC and the rat and mouse genome databases are provided. IUPHAR-DB is freely available at http://www.iuphar-db.org.

Published
2008

5. The Concise guide to pharmacology 2019/20: Introduction and Other Protein Targets

Author

Alexander, Stephen PH, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L., Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Fabbro, Doriano, Spedding, Michael, Striessnig, Jörg, Davies, Jamie A, Arumugam, Thiruma V, Bennett, Andrew, Sjögren, Benita, Sobey, Christopher, Wong, Szu Shen, Laboratory Genetic Metabolic Diseases, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, and Amsterdam Gastroenterology Endocrinology Metabolism

Subjects
0301 basic medicine, RM, Databases, Pharmaceutical, Computer science, Drug classification, Receptors, Cytoplasmic and Nuclear, Receptors, Cell Surface, Pharmacology, Ligands, Ion Channels, law.invention, 03 medical and health sciences, 0302 clinical medicine, Summary information, law, Animals, Humans, The Concise Guide to Pharmacology 2019/20, Clinical pharmacology, Proteins, 3. Good health, Protein Transport, 030104 developmental biology, Pharmaceutical Preparations, ATP-Binding Cassette Transporters, Catalytic receptors, 030217 neurology & neurosurgery
Abstract

The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (http://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14747. In addition to this overview, in which are identified Other protein targets which fall outside of the subsequent categorisation, there are six areas of focus: G protein‐coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

Published
2019
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6. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

Author

Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Fabbro, Doriano, Spedding, Michael, Striessnig, Jörg, Davies, Jamie A, Abbracchio, M. -P., Aldrich, R., Al-Hosaini, K., Arumugam, T. V., Attali, B., Bäck, M., Barnes, N. M., Bathgate, R., Beart, P. M., Becirovic, E., Bettler, B., Biel, M., Birdsall, N. J., Blaho, V., Boison, D., Bräuner-osborne, H., Bröer, S., Bryant, C., Burnstock, G., Calo, G., Catterall, W. A., Ceruti, S., Chan, S. L., Chandy, K. G., Chazot, P., Chiang, N., Chun, J. J., Chung, J. -J., Clapham, D. E., Clapp, L., Connor, M. A., Cox, H. M., Davies, P., Dawson, P. A., Decaen, P., Dent, G., Doherty, P., Douglas, S. D., Dubocovich, M. L., Fong, T. M., Fowler, C. J., Frantz, A., Fuller, P., Fumagalli, M., Futerman, A. H., Gainetdinov, R. R., Gershengorn, M. A., Goldin, A., Goldstein, S. A. N., Goudet, C., Gregory, K., Grissmer, S., Gundlach, A. L., Hagenbuch, B., Hamann, J., Hammond, J. R., Hancox, J. C., Hanson, J., Hanukoglu, I., Hay, D. L., Hobbs, A. J., Hollenberg, A. N., Holliday, N. D., Hoyer, D., Ijzerman, A. P., Inui, K. I., Irving, A. J., Ishii, S., Jacobson, K. A., Jan, L. Y., Jarvis, M. F., Jensen, R., Jockers, R., Kaczmarek, L. K., Kanai, Y., Karnik, S., Kellenberger, S., Kemp, S., Kennedy, C., Kerr, I. D., Kihara, Y., Kukkonen, J., Larhammar, D., Leach, K., Lecca, D., Leeman, S., Leprince, J., Lolait, S. J., Macewan, D., Maguire, J. J., Marshall, F., Mazella, J., Mcardle, C. A., Michel, M. C., Miller, L. J., Mitolo, V., Mizuno, H., Monk, P. N., Mouillac, B., Murphy, P. M., Nahon, J. -L., Nerbonne, J., Nichols, C. G., Norel, X., Offermanns, S., Palmer, L. G., Panaro, M. A., Papapetropoulos, A., Perez-reyes, E., Pertwee, R. G., Pintor, S., Pisegna, J. R., Plant, L. D., Poyner, D. R., Prossnitz, E. R., Pyne, S., Ramachandran, R., Ren, D., Rondard, P., Ruzza, C., Sackin, H., Sanger, G., Sanguinetti, M. C., Schild, L., Schiöth, H., Schulte, G., Schulz, S., Segaloff, D. L., Serhan, C. N., Singh, K. D., Slesinger, P. A., Snutch, T. P., Sobey, C. G., Stewart, G., Stoddart, L. A., Summers, R. J., Szabo, C., Thwaites, D., Toll, L., Trimmer, J. S., Tucker, S., Vaudry, H., Verri, T., Vilargada, J. -P., Waldman, S. A., Ward, D. T., Waxman, S. G., Wei, A. D., Willars, G. B., Wong, S. S., Woodruff, T. M., Wulff, H., Ye, R. D., Yung, Y., Zajac, J. -M., Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Fabbro, Doriano, Spedding, Michael, Striessnig, Jörg, Davies, Jamie A, Abbracchio, M. -P., Aldrich, R., Al-Hosaini, K., Arumugam, T. V., Attali, B., Bäck, M., Barnes, N. M., Bathgate, R., Beart, P. M., Becirovic, E., Bettler, B., Biel, M., Birdsall, N. J., Blaho, V., Boison, D., Bräuner-osborne, H., Bröer, S., Bryant, C., Burnstock, G., Calo, G., Catterall, W. A., Ceruti, S., Chan, S. L., Chandy, K. G., Chazot, P., Chiang, N., Chun, J. J., Chung, J. -J., Clapham, D. E., Clapp, L., Connor, M. A., Cox, H. M., Davies, P., Dawson, P. A., Decaen, P., Dent, G., Doherty, P., Douglas, S. D., Dubocovich, M. L., Fong, T. M., Fowler, C. J., Frantz, A., Fuller, P., Fumagalli, M., Futerman, A. H., Gainetdinov, R. R., Gershengorn, M. A., Goldin, A., Goldstein, S. A. N., Goudet, C., Gregory, K., Grissmer, S., Gundlach, A. L., Hagenbuch, B., Hamann, J., Hammond, J. R., Hancox, J. C., Hanson, J., Hanukoglu, I., Hay, D. L., Hobbs, A. J., Hollenberg, A. N., Holliday, N. D., Hoyer, D., Ijzerman, A. P., Inui, K. I., Irving, A. J., Ishii, S., Jacobson, K. A., Jan, L. Y., Jarvis, M. F., Jensen, R., Jockers, R., Kaczmarek, L. K., Kanai, Y., Karnik, S., Kellenberger, S., Kemp, S., Kennedy, C., Kerr, I. D., Kihara, Y., Kukkonen, J., Larhammar, D., Leach, K., Lecca, D., Leeman, S., Leprince, J., Lolait, S. J., Macewan, D., Maguire, J. J., Marshall, F., Mazella, J., Mcardle, C. A., Michel, M. C., Miller, L. J., Mitolo, V., Mizuno, H., Monk, P. N., Mouillac, B., Murphy, P. M., Nahon, J. -L., Nerbonne, J., Nichols, C. G., Norel, X., Offermanns, S., Palmer, L. G., Panaro, M. A., Papapetropoulos, A., Perez-reyes, E., Pertwee, R. G., Pintor, S., Pisegna, J. R., Plant, L. D., Poyner, D. R., Prossnitz, E. R., Pyne, S., Ramachandran, R., Ren, D., Rondard, P., Ruzza, C., Sackin, H., Sanger, G., Sanguinetti, M. C., Schild, L., Schiöth, H., Schulte, G., Schulz, S., Segaloff, D. L., Serhan, C. N., Singh, K. D., Slesinger, P. A., Snutch, T. P., Sobey, C. G., Stewart, G., Stoddart, L. A., Summers, R. J., Szabo, C., Thwaites, D., Toll, L., Trimmer, J. S., Tucker, S., Vaudry, H., Verri, T., Vilargada, J. -P., Waldman, S. A., Ward, D. T., Waxman, S. G., Wei, A. D., Willars, G. B., Wong, S. S., Woodruff, T. M., Wulff, H., Ye, R. D., Yung, Y., and Zajac, J. -M.

Subjects
Pharmacology
Abstract

The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full. In addition to this overview, in which are identified ‘Other protein targets’ which fall outside of the subsequent categorisation, there are eight areas of focus: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

Published
2017

7. [Untitled]

Author

Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Buneman, O Peter, Catterall, William A, Cidlowski, John A, Davenport, Anthony P, Fabbro, Doriano, Fan, Grace, McGrath, John C, Spedding, Michael, Davies, Jamie A, Aldrich, R, Attali, B, Bäck, Ml, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Biel, M, Birdsall, NJ, Boison, D, Bräuner‐Osborne, H, Bröer, S, Bryant, C, Burnstock, G, Burris, T, Cain, D, Calo, G, Chan, SL, Chandy, KG, Chiang, N, Christakos, S, Christopoulos, A, Chun, JJ, Chung, J‐J, Clapham, DE, Connor, MA, Coons, L, Cox, HM, Dautzenberg, FM, Dent, G, Douglas, SD, Dubocovich, ML, Edwards, DP, Farndale, R, Fong, TM, Forrest, D, Fowler, CJ, Fuller, P, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, SAN, Grimm, SL, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hammond, JR, Hancox, JC, Hartig, S, Hauger, RL, Hay, DL, Hébert, T, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, GE, Jensen, R, Jetten, A, Jockers, R, Kaczmarek, LK, Kanai, Y, Kang, HS, Karnik, S, Kerr, ID, Korach, KS, Lange, CA, Larhammar, D, Leeb‐Lundberg, F, Leurs, R, Lolait, SJ, Macewan, D, Maguire, JJ, May, JM, Mazella, J, Mcardle, CA, Mcdonnell, DP, Michel, MC, Miller, LJ, Mitolo, V, Monie, T, Monk, PN, Mouillac, B, Murphy, PM, Nahon, J‐L, Nerbonne, J, Nichols, CG, Norel, X, Oakley, R, Offermanns, S, Palmer, LG, Panaro, MA, Perez‐Reyes, E, Pertwee, RG, Pike, JW, Pin, JP, Pintor, S, Plant, LD, Poyner, DR, Prossnitz, ER, Pyne, S, Ren, D, Richer, JK, Rondard, P, Ross, RA, Sackin, H, Safi, R, Sanguinetti, MC, Sartorius, CA, Segaloff, DL, Sladek, FM, Stewart, G, Stoddart, LA, Striessnig, J, Summers, RJ, Takeda, Y, Tetel, M, Toll, L, Trimmer, JS, Tsai, M‐J, Tsai, SY, Tucker, S, Usdin, TB, Vilargada, J‐P, Vore, M, Ward, DT, Waxman, SG, Webb, P, Wei, AD, Weigel, N, Willars, GB, Winrow, C, Wong, SS, Wulff, H, Ye, RD, Young, M, and Zajac, J‐M

Subjects
Pharmacology, Summary information, business.industry, The Concise Guide to PHARMACOLOGY 2015/16, Medicine, Catalytic receptors, business, 3. Good health
Abstract

The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.

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