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Your search keyword '"Taqi, Zainab J."' showing total 2 results
Start Over Author "Taqi, Zainab J." Topic phagocytosis
2 results on '"Taqi, Zainab J."'

1. Potential Activity of Silver Nanoparticles Synthesized by Iraqi propolis on phagocytosis.

Author

Taqi, Zainab J., Abdul-wahed, Hamssa E., AL-Saadi, Huda K., and Jabir, Majid. S.

Subjects
*SILVER nanoparticles, *PROPOLIS, *OPTICAL spectroscopy, *PHAGOCYTOSIS
Abstract

This study aimed to synthesis and characterized silver nanoparticles using Iraqi propolis then inversigate their ability in induce of phagocytic cells. The Synthesis of Silver nanoparticles by on the green synthesis was confirmed using different parameters, color changes, and then conformed by of UV visible spectroscopy. The morphology was characterized by SEM. Moreover, their effectiveness in stimulation of Phagocytosis had been studied. The results showed significant increases in the ability of phagocytic cells in the presence of nanoparticles as compared with non-treated cells. The results suggested that silver nanoparticles synthesis using Iraqi propolis act as immunomodeulater and could be used for pharmaceutical applications. [ABSTRACT FROM AUTHOR]

Published
2020
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2. Gold Nanoparticles and Graphene Oxide Flakes Enhance Cancer Cells' Phagocytosis through Granzyme-Perforin-Dependent Biomechanism.

Author

Al-Omar, Mohsen S., Jabir, Majid, Karsh, Esraa, Kadhim, Rua, Sulaiman, Ghassan M., Taqi, Zainab J., Khashan, Khawla S., Mohammed, Hamdoon A., Khan, Riaz A., and Mohammed, Salman A. A.

Subjects
CANCER cells, GRAPHENE oxide, PHAGOCYTOSIS, GOLD nanoparticles, PROTEASE inhibitors, NANOSTRUCTURED materials
Abstract

The study aimed to investigate the roles of gold nanoparticles (GNPs) and graphene oxide flakes (GOFs) as phagocytosis enhancers against cancer cells. The nanomaterials were characterized through SEM and UV-VIS absorptions. The GNPs and GOFs increased the macrophages' phagocytosis ability in engulfing, thereby annihilating the cancer cells in both in vitro and in vivo conditions. The GNPs and GOFs augmented serine protease class apoptotic protein, granzyme, passing through the aquaporin class protein, perforin, with mediated delivery through the cell membrane site for the programmed, calibrated, and conditioned cancer cells killing. Additionally, protease inhibitor 3,4-dichloroisocoumarin (DCI) significantly reduced granzyme and perforin activities of macrophages. The results demonstrated that the GOFs and GNPs increased the activation of phagocytic cells as a promising strategy for controlling cancer cells by augmenting the cell mortality through the granzyme-perforin-dependent mechanism. [ABSTRACT FROM AUTHOR]

Published
2021
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