1. Endoscopic full-thickness resection of colonic submucosal tumors originating from the muscularis propria: an evolving therapeutic strategy
- Author
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Wei-Feng Chen, Quan-Lin Li, Yi-Qun Zhang, Jian-Wei Hu, Lili Ma, Ping-Hong Zhou, Mei-Dong Xu, Xiao-Yun Wang, Sauid Ishaq, Li-Qing Yao, Yun-Shi Zhong, and Wen-Zheng Qin
- Subjects
Adult ,Male ,medicine.medical_specialty ,Tumor capsule ,Perforation (oil well) ,Colonoscopy ,Peritonitis ,Pilot Projects ,Postoperative Complications ,Humans ,Medicine ,Endoscopic resection ,Full thickness resection ,Laparoscopy ,Aged ,Therapeutic strategy ,Aged, 80 and over ,medicine.diagnostic_test ,Wound Closure Techniques ,business.industry ,Gastroenterology ,Middle Aged ,medicine.disease ,Surgery ,Colonic Neoplasms ,Female ,business - Abstract
Endoscopic resection of colonic submucosal tumors (SMTs) is challenging and carries a high risk of perforation. In this prospective pilot study we aimed to evaluate the feasibility, safety, and efficacy of endoscopic full-thickness resection of colonic SMTs. The study enrolled 19 consecutive patients with colonic SMTs 3 cm in size or smaller. In 18 of the 19 patients full-thickness resection was carried out endoscopically with the entire tumor capsule intact. In 16 of these18 patients, full-thickness resection was carried out and the colonic wall defect closed all endoscopically; in the other 2 patients, laparoscopic closure was needed. Two cases of local peritonitis were managed with conservative treatment. No deaths occurred within 30 days, and no recurrence was detected after a median of 18 months' follow-up. Endoscopic full-thickness resection is a novel method enabling resection of colonic SMTs. The colonic wall mucosal defect can be closed endoscopically in the majority of cases. It appears to be a safe and effective endoscopic technique for managing these tumors, which traditionally are managed by colonic resection.
- Published
- 2013