1. Fetal intestinal perforation and meconium peritonitis associated with maternal autoimmune hepatitis.
- Author
-
Charlagorla P, Sublett S, Sy F, Kessler E, and Gad A
- Subjects
- Adult, Ampicillin therapeutic use, Anti-Bacterial Agents therapeutic use, Azathioprine adverse effects, Enterococcus faecalis isolation & purification, Female, Gentamicins therapeutic use, Gram-Positive Bacterial Infections surgery, Hepatitis, Autoimmune drug therapy, Humans, Ileostomy, Immunosuppressive Agents adverse effects, Infant, Newborn, Infant, Premature, Intestinal Perforation microbiology, Intestinal Perforation surgery, Laparotomy, Male, Meconium microbiology, Peritonitis microbiology, Peritonitis surgery, Pregnancy, Pregnancy Outcome, Risk Factors, Treatment Outcome, Ultrasonography, Gram-Positive Bacterial Infections drug therapy, Hepatitis, Autoimmune complications, Intestinal Perforation diagnostic imaging, Meconium diagnostic imaging, Peritonitis diagnostic imaging, Pregnancy Complications, Infectious drug therapy
- Abstract
Autoimmune hepatitis (AIH) in pregnancy can affect both fetal and maternal outcomes. Little is known regarding the fetal outcomes of AIH in pregnancy. The major risks include spontaneous abortions, fetal mortality, perinatal mortality and prematurity. Two common drugs used in the management of AIH, azathioprine and prednisone, may also be associated with adverse fetal outcomes. We present the case of perinatal focal intestinal perforation with a meconium pseudocyst in a preterm infant of a mother with autoimmune hepatitis on azathioprine and methylprednisone.
- Published
- 2014
- Full Text
- View/download PDF