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1. [Induced variability in Acremonium chrysogenum, a producer of neutral-alkaline proteases and peptidases].

Author

Domracheva AG, Bartoshevich IuE, Iudina OD, Golubeva SA, and Bespalova OI

Subjects
Acremonium classification, Acremonium enzymology, Acremonium genetics, Enzyme Induction drug effects, Methionine pharmacology, Mutation, Nitrosamines pharmacology, Protease Inhibitors, Acremonium drug effects, Genetic Variation drug effects, Peptide Hydrolases biosynthesis
Abstract

Lethal and mutagenic effects of N-nitrosomethyl biuret on the organism producing a complex of proteolytic enzymes i. e. Acremonium chrysogenum were studied. It was shown that methionine inhibited production of the protease complex in the induced prototrophic mutants. The selected mutants were classified according to the level of enzyme biosynthesis induction by methionine.

Published
1988

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