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1. New Clinical Trial Research Findings from Al-Azhar University Discussed (A Unique Application of Pentane-2,4-dione As a Fluorogenic Probe of Dipeptidyl Peptidase-4 Enzyme Inhibitor Medicament Assay In Pharmaceutical and Biological Matrices>).

Subjects
CD26 antigen, BIOLOGICAL assay, CLINICAL trials, ENZYME inhibitors, MEDICAL research
Abstract

Researchers from Al-Azhar University in Assiut, Egypt have developed a new method for assessing the drug sitagliptin (STG), which is used to manage type 2 diabetes. The method involves using a dihydropyridine derivative called pentane-2,4-dione to create a fluorescent molecule that can be measured using spectrofluorimetry. The researchers found that this method was simple, effective, and quick, making it a useful tool for quality control and clinical study assays of STG. This research has been peer-reviewed and provides valuable insights for pharmaceutical and biological matrices. [Extracted from the article]

Published
2023