Search

Purpose: Pelvic lymph node (PLN) metastases are often smaller than 5 mm and difficult to detect. This work presents a method to perform PLN imaging with ultrahigh-field MRI, using spectrally selective excitation to acquire water and lipid-selective imaging at high spatial resolution., Methods: A 3D water-selective multigradient echo (mGRE) sequence and lipid-selective gradient echo (GRE) sequence were tested in six healthy volunteers on a 7 Tesla (T) MRI system, using time interleaved acquisition of modes (TIAMO) to improve image homogeneity. The size distribution of the first 10 iliac PLNs detected in each volunteer was determined, and the contrast-to-noise ratio (CNR) of these lymph nodes (LNs) was compared with the individual mGRE images, sum-of-squares echo addition, and computed T2*-weighted images derived from the T2* fits., Results: LN imaging was acquired robustly at ultrahigh field with high resolution and homogeneous lipid or water-selective contrast. PLNs down to 1.5-mm short axis were detected with mean ± standard error of the mean (SEM) short and long axes of 2.2 ± 0.1 and 3.7 ± 0.2 mm, respectively. Computed T2*-weighted imaging allowed flexibility in T2* contrast while featuring a CNR up to 90% of the sum-of-squares echo addition., Conclusion: Ultrahigh-field MRI in combination with TIAMO and frequency-selective excitation enables high-resolution, large field-of-view MRI of the lower abdomen, and may ultimately be suitable for detecting small PLN metastases. Magn Reson Med 78:1020-1028, 2017. © 2016 International Society for Magnetic Resonance in Medicine., (© 2016 International Society for Magnetic Resonance in Medicine.)

Objectives: The aim of this study was to investigate the feasibility of 7-T contrast-enhanced MR imaging of the female pelvis., Methods: Ten healthy female volunteers were examined on a 7-T whole-body MR system utilising a custom-built eight-channel transmit/receive radiofrequency body coil. The examination protocol included (1) T1-weighted fat-saturated 2D spoiled gradient echo (FLASH), (2) dynamic T1-weighted fat-saturated 3D FLASH, and (3) T2-weighted TSE sequences. For qualitative image analysis pelvic anatomy, uterine zonal anatomy and image impairment due to artefacts was assessed using a five-point scale. For quantitative analysis contrast ratios between the junctional zone and myometrium were obtained for T2-weighted MRI., Results: Two-dimensional FLASH MRI offered the best overall image quality (meancontrast-enhanced 4.9) and highest tissue contrast (meancontrast-enhanced 4.7). T2-weighted TSE imaging provided a moderate to high conspicuity of the uterine zonal anatomy with mean scores ranging from 3.5 for endometrium to 4.65 for myometrium. Overall image impairment was rated strongest for T2-weighted MRI (2.9) and least for 2D FLASH MRI (mean 4.2)., Conclusion: This study demonstrated the feasibility of 7-T T1-weighted MRI of the female pelvis and current constraints associated with T2-weighted MRI., Key Points: • Dynamic contrast-enhanced female pelvis MR imaging at 7 T is feasible. • Unenhanced T1-weighted MRI offers inherent hyperintense delineation of pelvic arterial vasculature. • Two-dimensional FLASH MRI provided best overall image quality and least artefact impairment.

In magnetic resonance imaging, there has been a constant drive to higher static magnetic field strengths (B0) to achieve a higher signal-to-noise ratio and new or enhanced contrasts. In today's high-field systems, severe problems regarding the homogeneity of the transmission field are encountered. Recently, an acquisition scheme called Time-Interleaved Acquisition of Modes has been proposed to tackle the inhomogeneity problems in high-field magnetic resonance imaging. The basic premise is to excite two (or more) different B1(+) modes using static radiofrequency shimming in an interleaved acquisition, where the complementary radiofrequency patterns of the two modes can be exploited to improve overall signal homogeneity. In its usual implementation, a multichannel transmit system is required. In this work, the goal is to present a simple and inexpensive hardware setup which makes it possible to use time-interleaved acquisition of modes on any single-channel transmit system while making use of the vendor-provided single-channel radiofrequency safety system. To demonstrate the efficacy of this setup, spin echo images from the pelvis are acquired at 7 T exhibiting no complete signal dropouts., (Copyright © 2012 Wiley Periodicals, Inc.)

Objective: The definition of an in vivo nodal anatomical baseline is crucial for validation of representative lymph node dissections and accompanying pathology reports of pelvic cancers, as well as for assessing a potential therapeutic effect of extended lymph node dissections. Therefore the number, size and distribution of lymph nodes in the pelvis were assessed with high-resolution, large field-of-view, 7 Tesla (T) magnetic resonance imaging (MRI) with frequency-selective excitation. Materials and methods: We used 7 T MRI for homogeneous pelvic imaging in 11 young healthy volunteers. Frequency-selective imaging of water and lipids was performed to detect nodal structures in the pelvis. Number and size of detected nodes was measured and size distribution per region was assessed. An average volunteer-normalized nodal size distribution was determined. Results: In total, 564 lymph nodes were detected in six pelvic regions. Mean number was 51.3 with a wide range of 19–91 lymph nodes per volunteer. Mean diameter was 2.3 mm with a range of 1 to 7 mm. 69% Was 2 mm or smaller. The overall size distribution was very similar to the average volunteer-normalized nodal size distribution. Conclusions: The amount of in vivo visible lymph nodes varies largely between subjects, whereas the normalized size distribution of nodes does not. The presence of many small lymph nodes (≤2mm) renders representative or complete removal of pelvic lymph nodes to be very difficult. 7T MRI may shift the in vivo detection limits of lymph node metastases in the future. [ABSTRACT FROM AUTHOR]

Purpose: In this work, a combined body coil array with eight transmit/receive (Tx/Rx) meander elements and with 24 receive‐only (Rx) loops (8Tx/32Rx) was developed and evaluated in comparison with an 8‐channel transmit/receive body array (8Tx/Rx) based on meander elements serving as the reference standard. Methods: Systematic evaluation of the RF array was performed on a body‐sized phantom. Body imaging at 7T was performed in six volunteers in the body regions pelvis, abdomen, and heart. Coil characteristics such as signal‐to‐noise ratio, acceleration capability, g‐factors, S‐parameters, noise correlation, and B1+ maps were assessed. Safety was ensured by numerical simulations using a coil model validated by dosimetric field measurements. Results: Meander elements and loops are intrinsically well decoupled with a maximum coupling value of −20.5 dB. Safe use of the 8Tx/32Rx array could be demonstrated. High gain in signal‐to‐noise ratio (33% in the subject's center) could be shown for the 8Tx/32Rx array compared to the 8Tx/Rx array. Improvement in acceleration capability in all investigations could be demonstrated. For example, the 8Tx/32Rx array provides lower g‐factors in the right–left and anterior–posterior directions with R = 3 undersampling as compared to the 8Tx/Rx array using R = 2. Both arrays are very similar regarding their RF transmit performance. Excellent image quality in the investigated body regions could be achieved with the 8Tx/32Rx array. Conclusion: In this work, we show that a combination of eight meander elements and 24 loop receive elements is possible without impeding transmit performance. Improved SNR and g‐factor performance compared to an RF array without these loops is demonstrated. Body MRI at 7T with the 8Tx/32Rx array could be accomplished in the heart, abdomen, and pelvis with excellent image quality. [ABSTRACT FROM AUTHOR]