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3 results on '"Silvia Braibanti"'

1. Neuroprem 2: An Italian Study of Neurodevelopmental Outcomes of Very Low Birth Weight Infants

Author

Licia Lugli, Luca Bedetti, Isotta Guidotti, Marisa Pugliese, Odoardo Picciolini, Maria Federica Roversi, Elisa DellaCasa Muttini, Laura Lucaccioni, Natascia Bertoncelli, Gina Ancora, Giancarlo Gargano, Fabio Mosca, Fabrizio Sandri, Luigi Tommaso Corvaglia, Agostina Solinas, Serafina Perrone, Marcello Stella, The Neuroprem Working Group, Lorenzo Iughetti, Alberto Berardi, Fabrizio Ferrari, Antonella Luglio, Sara Grandi, Valentina Fiorini, Piero Catenazzi, Elisa Ballardini, Sabrina Moretti, Daniela Turoli, Arianna Aceti, Roberto Bellù, Luca Ori, Silvia Braibanti, Alessandra Boncompagni, Caterina Spada, and Lara Valeri

Subjects
very low birth weight, preterm, neuro-developmental outcome, follow-up, network, Pediatrics, RJ1-570
Abstract

Background: Despite the increased survival of preterm newborns worldwide, the risk of neurodevelopmental disabilities remains high. Analyzing the outcomes of the preterm population can identify risk factors and enable specific early interventions.Aims: Neuroprem is a prospective cohort study of very low birth weight (VLBW) infants that aims to evaluate the neurodevelopmental outcomes and risk factors for severe functional disability at 2 years of corrected age.Methods: Nine Italian neonatal intensive care units participated in the network. The Griffiths Mental Developmental Scales (GMDS-R) or the Bayley Scales of Infant and Toddler Development (BSDI III) and a neuro-functional evaluation (according to the International Classification of Disability and Health and Neuro-Functional Assessment, or NFA ICF-CY) were administered to VLBW infants at 24 months of corrected age. The primary outcome measure was severe functional disability, defined as cerebral palsy, bilateral blindness, deafness, an NFA ICF-CY of >2, a BSDI III cognitive composite score of

Published
2021
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2. Neuroprem: the Neuro-developmental outcome of very low birth weight infants in an Italian region

Author

Licia Lugli, Marisa Pugliese, Carlotta Plessi, Alberto Berardi, Isotta Guidotti, Gina Ancora, Sara Grandi, Giancarlo Gargano, Silvia Braibanti, Fabrizio Sandri, Silvia Soffritti, Elisa Ballardini, Vittoria Arena, Marcello Stella, Serafina Perrone, Sabrina Moretti, Vittoria Rizzo, Fabrizio Ferrari, Neuroprem Working Group, Odoardo Picciolini, Roberto Bellù, Daniela Turoli, Luigi Tommaso Corvaglia, Gianpaolo Garani, Vittoria Paoletti, Giacomo Biasucci, Augusto Biasini, Belinda Benenati, Paolo Stagi, Cristina Magnani, Sara Dallaglio, Elisa DellaCasa Muttini, Maria Federica Roversi, Luca Bedetti, Laura Lucaccioni, Natascia Bertoncelli, and Alessandra Boncompagni

Subjects
Neuro-developmental outcome, Very low birth weight preterm, Italy, Pediatrics, RJ1-570
Abstract

Abstract Introduction The survival of preterm babies has increased worldwide, but the risk of neuro-developmental disabilities remains high, which is of concern to both the public and professionals. The early identification of children at risk of neuro-developmental disabilities may increase access to intervention, potentially influencing the outcome. Aims Neuroprem is an area-based prospective cohort study on the neuro-developmental outcome of very low birth weight (VLBW) infants that aims to define severe functional disability at 2 years of age. Methods Surviving VLBW infants from an Italian network of 7 neonatal intensive care units (NICUs) were assessed for 24 months through the Griffiths Mental Developmental Scales (GMDS-R) or the Bayley Scales of Infant and Toddler Development (BSDI III) and neuro-functional evaluation according to the International Classification of Disability and Health (ICF-CY). The primary outcome measure was severe functional disability at 2 years of age, defined as cerebral palsy, a BSDI III cognitive composite score

Published
2020
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3. Development of epilepsy in newborns with moderate hypoxic-ischemic encephalopathy and neonatal seizures

Author

Emanuela Claudia Turco, Francesco Pisani, Silvia Braibanti, Cristiana Copioli, Lisa Sisti, and Manuela Orsini

Subjects
Pediatrics, medicine.medical_specialty, Neonatal intensive care unit, Birth weight, Encephalopathy, Severity of Illness Index, Hypoxic Ischemic Encephalopathy, Cerebral palsy, Epilepsy, Asphyxia, Developmental Neuroscience, Risk Factors, Seizures, medicine, Birth Weight, Humans, Prospective Studies, Asphyxia Neonatorum, business.industry, Infant, Newborn, Brain, Electroencephalography, General Medicine, Neonatal seizures, Term newborns, medicine.disease, Perinatal asphyxia, Pediatrics, Perinatology and Child Health, Hypoxia-Ischemia, Brain, Apgar Score, Neurology (clinical), medicine.symptom, business, Follow-Up Studies
Abstract

Background: Hypoxic-ischemic encephalopathy (HIE) is one of the most frequent causes of neonatal death or neurological handicaps such as cerebral palsy, mental delay, and epilepsy. Moreover, an acute consequence of HIE are neonatal seizures which can cause an additional brain damage. The neurodevelopmental outcome is known in the mild or severe cases of HIE, but in the moderate conditions the predictivity results, to date, unsatisfying. Objective: The purpose of this prospective study was to appraise the development of post-neonatal epilepsy in a cohort of term infants with moderate HIE and neonatal seizures. Methods: This study considered all newborns admitted to Neonatal Intensive Care Unit of the University of Parma between January 2000 and December 2002 for perinatal asphyxia, then followed by Neonatal Neurology Service. In all patients, neonatal variables such as type of delivery, birth weight, gestational age, Apgar scores, the need for resuscitation and assisted ventilation soon after birth, and arterial-blood pH were analyzed. Results: Ninety-two newborns were enrolled in the study because of perinatal asphyxia. Of these, 27 subjects developed mild HIE, 25 moderate, and five severe HIE. Neonatal seizures were present in 13 subjects with moderate HIE and in all newborns with severe HIE. At the last follow-up, only three infants belonging to patients with severe HIE developed epilepsy. Conclusion : Moderate HIE seems not to be related to post-neonatal epilepsy either if associated or not with neonatal seizures.

Published
2008

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