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3 results on '"Antonio Salcedo Posadas"'

1. Follow-up protocol of patients with cystic fibrosis diagnosed by newborn screening

Author

Silvia Gartner, Pedro Mondéjar-López, Óscar Asensio de la Cruz, María José Alonso, Marina Álvarez, Anselmo Andrés Martín, María Isabel Barrio Gómez de Agüero, María Jesús Cabero Pérez, Pilar Caro Aguilera, María Cols Roig, Isidoro Cortell Aznar-Pérez, Jordi Costa Colomer, Isabel Delgado Pecellín, Amparo Escribano Montaner, Joan Figuerola Mulet, Gloria García Hernández, Pilar Guayarte, David Gil Ortega, David Gómez Pastrana, Adelaida Lamas Ferreiro, José Luis Marín Soria, Carlos Martín de Vicente, Martín Navarro Merino, Concepción Oliva Hernández, Javier Pérez Frías, Estela Pérez Ruiz, Sandra Rovira Amigo, Antonio Salcedo Posadas, Manuel Sánchez-Solís, Josep Sirvent Gómez, Carlos Vázquez Cordero, and José Ramón Villa Asensi

Subjects
Fibrosis quística, Cribado neonatal, Protocolo de diagnóstico y seguimiento, Pediatrics, RJ1-570
Abstract

Newborn screening (NBS) for cystic fibrosis (CF) is well-established in many countries and provides the opportunity for an early diagnosis and treatment before the development of irreversible structural lung damage.In 1999, Catalonia, Castilla-León, and the Balearic Islands started the NBS programme for CF. In the last 10 years its implementation rapidly spread and all the autonomies offer the NBS programme for CF since 2015. There are many different strategies across Spain. It is believed that it is very opportune to have an updated and consensual guide for the diagnosis, follow-up, and treatment of patients diagnosed by neonatal screening. Resumen: El diagnóstico de fibrosis quística (FQ) a través del cribado neonatal (CN) está bien establecido en muchos países y brinda la oportunidad de un diagnóstico y tratamiento temprano antes del desarrollo de daño estructural pulmonar irreversible.En 1999, Cataluña, Castilla-León y las Islas Baleares iniciaron el programa CN para FQ. En los últimos 10 años su implementación se extendió rápidamente y todas las autonomías ofrecen el programa CN para FQ desde 2015. Hay varias estrategias diferentes en toda España. Creemos que es muy oportuno contar con una guía actualizada y consensuada para el diagnóstico, el seguimiento y el tratamiento de los pacientes diagnosticados de FQ mediante CN.

Published
2019
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2. RESPIRATORY OUTCOMES OF 'NEW' BRONCHOPULMONARY DYSPLASIA IN ADOLESCENTS: A MULTICENTER STUDY

Author

Maria Arroyas Sanchez, Roser Ayats Vidal, María Luz García-García, Jordi Costa Colomer, Xavier Domingo Miró, Antonio Salcedo Posadas, Alicia Callejón Callejón, Ana Villares Porto‐Dominguez, Salome Albi Rodriguez, Santiago Rueda Esteban, Inés de Mir Messa, Elisa María Canino Calderín, Montserrat Berrocal Castañeda, Orlando Mesa Medina, Santiago Pérez‐Tarazona, and Tatiana Acevedo Valarezo

Subjects
Pulmonary and Respiratory Medicine, Pediatrics, medicine.medical_specialty, Vital capacity, Adolescent, medicine.drug_class, Outcomes, chronic lung disease, behavioral disciplines and activities, Pulmonary function testing, 03 medical and health sciences, FEV1/FVC ratio, 0302 clinical medicine, Quality of life, Pregnancy, Forced Expiratory Volume, 030225 pediatrics, Bronchodilator, mental disorders, medicine, Humans, Bronchopulmonary Dysplasia, Asthma, business.industry, prematurity, pulmonary function, Original Articles, asthma, medicine.disease, Cross-Sectional Studies, 030228 respiratory system, Bronchopulmonary dysplasia, Pediatrics, Perinatology and Child Health, Quality of Life, Gestation, Original Article, Female, business, Infant, Premature
Abstract

Objective Long‐term respiratory consequences of bronchopulmonary dysplasia (BPD) in preterm infants born in the post‐surfactant era (“new” BPD) remain partially unknown. The present study aimed to evaluate the respiratory outcomes of “new” BPD in adolescents who were born preterm. Methods This multicenter, cross‐sectional study included 286 adolescents born between 2003 and 2005 (mean age: 14.2 years); among them, 184 and 102 were born extremely preterm (EP

Published
2020
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3. Comorbidities and course of lung function in patients with congenital esophageal atresia

Author

Sara Bellón Alonso, Gonzalo Solís-García, Ana Jové Blanco, Antonio Salcedo Posadas, Ana Gutiérrez Vélez, and Juan Luis Rodríguez Cimadevilla

Subjects
Spirometry, Male, medicine.medical_specialty, Pediatrics, Population, Vital Capacity, Pulmonary function testing, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Internal medicine, Forced Expiratory Volume, medicine, Humans, Longitudinal Studies, Risk factor, education, Esophageal Atresia, Asthma, Retrospective Studies, education.field_of_study, medicine.diagnostic_test, business.industry, Infant, Newborn, medicine.disease, Pneumonia, Pulmonology, 030228 respiratory system, Atresia, Pediatrics, Perinatology and Child Health, Female, business
Abstract

To describe the epidemiological characteristics, hospital follow-up, and course of patients who underwent surgery for esophageal atresia and its consequences on lung function.Retrospective, longitudinal, and analytical study. The medical records of patients with esophageal atresia born between 1996 and 2017 were reviewed. Perinatal data, type of atresia, associated malformations, respiratory and gastrointestinal complications, and spirometry data were recorded over 3 years.A total of 97 patients were included. The most common type of atresia was III, and the most frequent syndrome, trisomy 21; 13.4 % of patients died in the neonatal period; 23.8 % were followed up by the Department of Pulmonology, and their respiratory complications included exacerbations (46.4 %), wheezing or asthma (36 %), and pneumonia (26.8 %). Gastroesophageal reflux was a risk factor for wheezing (OR: 5.31;In our sample of patients, a large proportion had respiratory and gastrointestinal comorbidities. Lung function worsened progressively.Objetivo: Describir las características epidemiológicas, el seguimiento hospitalario y la evolución de los pacientes intervenidos por atresia esofágica y su repercusión en la función pulmonar. Población y métodos: Estudio retrospectivo, longitudinal y analítico. Se revisaron las historias clínicas de pacientes con atresia esofágica nacidos entre 1996 y 2017. Se registraron datos perinatales, tipo de atresia, malformaciones asociadas, complicaciones respiratorias y digestivas, y los datos espirométricos durante tres años. Resultados: Se incluyeron 97 pacientes. El tipo de atresia más frecuente fue el III y el síndrome más frecuente, la trisomía 21. El 13,4 % fallecieron en el período neonatal. El 23,8 % de los pacientes estuvo en seguimiento por Neumología y presentó como complicaciones respiratorias exacerbaciones (el 46,4 %), sibilancias o asma (el 36 %), neumonías (el 26,8 %). El reflujo gastroesofágico fue factor de riesgo de sibilancias (OR 5,31; p = 0,002), exacerbaciones (OR 4,00; p = 0,009) y neumonías (OR 3,24; p = 0,02). En la primera espirometría (n = 20), un 65 % presentaba patrón normal; un 30 %, restrictivo, y un 5 %, mixto. En la segunda espirometría (n = 19), un 42,1 % presentaba patrón normal; un 31,6 %, restrictivo; un 15,8 %, obstructivo, y un 10,5 %, mixto. En la tercera espirometría (n = 14), el 50 % presentaba un patrón espirométrico normal; el 21,4 %, restrictivo; el 14,3 %, obstructivo, y un 14,3 %, mixto. Conclusiones: En nuestra muestra de pacientes, una importante proporción presentó comorbilidades respiratorias y digestivas. La función pulmonar empeoró progresivamente.

Published
2019

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