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Background: Smoking is the most common cause of preventable death and disease. Our country is one of the European countries with a high smoking rate. With the effect of social awareness, education and social situations, applications to smoking cessation outpatient clinics are increasing. In this study, we aimed to discuss both smoking cessation in our outpatient clinic and the effect of a standard 12-week varenicline regimen for smoking cessation and a standard 10-week transdermal nicotine replacement therapy (NRT) regimen on cessation. Materials and Methods: 845 patients who applied to smoking cessation clinic between January 2015 andJanuary 2018 were started retrospectively. Results: The patients included in the study were compared according to their smoking cessation status. There was no statistically significant difference between the two groups in terms of age and gender (p=0.622, p=0.241). While the Fagerstrom Nicotine Dependence Score (FNBS) was 6.12±0.9 in the group who quit smoking, it was 8.45±1.1 in the group who did not quit smoking, and there was a statistically significant difference between the groups (p=0.04). 80.5% of the patients used varenicline, 19.5% of them used nicotine patch. The patients were compared according to the drug they took. There was no statistically significant difference between Varenicline and nicotine patch in smoking cessation (p=0.707). In addition, the two groups were compared in terms of age and gender. While there was a significant difference between the two groups in terms of age (p<0.001), there was no significant difference in terms of gender (p=0.405). While FNBS was 6.95±0.9 in the varenicline group, it was 7.01±0,7 in the NRT group, and there was no significant difference between the two groups (p=0.506). Conclusions: It was observed that demographic characteristics such as age and gender did not affect smoking cessation, but low FNBS was effective in quitting smoking. In addition, it was determined that there was no difference between drugs in smoking cessation. [ABSTRACT FROM AUTHOR]

OBJECTIVE: Quitting smoking is essential for good health, and the number of applicants to smoking cessation clinics is growing. This study explored the factors contributing to effective smoking cessation programmes and the impact of different treatment modalities for patients who are trying to quit. MATERIAL AND METHODS: Four hundred patients admitted to a smoking cessation clinic were included in this retrospective study. Treatment outcomes were evaluated at the end of the third month. Demographic characteristics, smoking behaviour and attitudes, Fagerström test results, and the use of medications were recorded. RESULTS: The overall smoking cessation rate of the cohort was 36.5%. The mean age of patients who successfully quit was slightly higher than those who continued (p<0.05), but other demographics were similar. The daily number of cigarettes smoked was greater in the group that did not quit (p<0.05). Patients received different treatment modalities including behavioural therapy (BT; 30.5%), BT plus nicotine replacement therapy (14.5%), BT plus bupropion (21%), and BT plus varenicline (34%). The success rate of each strategy was 18.9%, 36.2%, 39.3%, and 50.7%, respectively, and these differences were statistically significant (p<0.001 ). In addition, longer duration of treatment increased the likelihood of success. CONCLUSION: Smoking cessation is a difficult and time-consuming process. Smokers should receive a combination of behavioural and pharmacological therapies tailored to the individual. The longer that these strategies are in place, the greater the chance of success in smoking cessation programmes. [ABSTRACT FROM AUTHOR]

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Objective: Smoking is an important contributor to respiratory diseases and is the major etiological factor for the development of chronic obstructive pulmonary disease (COPD) and adversely affects control of asthma. For this reason, smoking cessation is the one of the most important ways to improve the prognosis of patients with respiratory disease. Our aim was to determine the characteristics with the long-term smoking cessation rates of outpatients with COPD and asthma and compared the differences between the diseases. Material and Method: 42 smokers with COPD and 28 asthma patients were prospectively evaluated in 2007. All of the patients answered the Fagerstrom test with a regular questionnaire of general characteristics. Baseline spirometry and CO oximetry were performed. The 24 months follow-up results and demographic characteristics were reported. Results: COPD patients were older and the total amount of smoked cigarettes was higher with an evident airway obstruction. In the first year, the smoking cessation rate was less with high tobacco dependence relapses in outpatients with asthma (32% and 18%) compared with COPD (55% and 9%). Asthma patients were predominantly women and cessation rates were quite low with higher relapse rates in women compared with men. At the end of 2 years follow up, smoking cessation rates for COPD was 45%, whereas this was 18% for asthma, which was dramatically low. Conclusion: Results of this analysis confirm that smoking cessation is still a huge problem to be solved in respiratory diseases. Even if smoking is not an etiological factor in asthma, tobacco dependence is more severe and long-term cessation rates are very low with high relapses. [ABSTRACT FROM AUTHOR]