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Ascites is uncommon in patients with hypothyroidism. Herein we describe an 84-year-old female patient with myxedema ascites that resolved completely with thyroid replacement medication. Bacteriological studies of the ascitic fluid revealed gram-negative rods which eventually proved to be Klebsiella pneumoniae treated successfully with antibiotics. Our review of the literature failed to reveal a previous case of myxedema ascites with concomitant subclinical spontaneous bacterial peritonitis. Copyright © 2003 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

We report the case of a 26-yr-old patient with fulminant liver failure and acute hemorrhagic pancreatitis secondary to the use of trimethoprim-sulfamethoxazole (Bactrim DS). Our patient presented with skin rash and decreased C3 and C4 levels, which we believed was due to a hypersensitivity reaction secondary to the sulfonamide component (sulfamethoxazole). To our knowledge, this is the first case reported in which suffamethoxazole-trimethoprim has been implicated as a cause of fulminant liver failure and acute hemorrhagic pancreatitis simultaneously, and emphasizes the need of discontinuing this medication as soon as there is evidence of liver and pancreatic dysfunction. [ABSTRACT FROM AUTHOR]