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6 results on '"Pennazio, F"'

1. Elemental fragmentation cross sections for a 16O beam of 400 MeV/u kinetic energy interacting with a graphite target using the FOOT ΔE-TOF detectors

Author

Toppi, M., Sarti, A., Alexandrov, A., Alpat, B., Ambrosi, G., Argirò, S., Diaz, R. A., Barbanera, M., Bartosik, N., Battistoni, G., Belcari, N., Biondi, S., Bisogni, M. G., Bon, M., Bruni, G., Carra, P., Cavanna, F., Cerello, P., Ciarrocchi, E., Clozza, A., Colombi, S., De Lellis, G., De Gregorio, A., Del Guerra, A., De Simoni, M., Di Crescenzo, A., Di Ruzza, B., Donetti, M., Dong, Y., Durante, M., Ferrero, V., Fiandrini, E., Finck, C., Fiorina, E., Fischetti, M., Francesconi, M., Franchini, M., Franciosini, G., Galati, G., Galli, L., Giraudo, G., Hetzel, Ronja Karin, Iarocci, E., Ionica, M., Iuliano, A., Kanxheri, K., Kraan, A. C., La Tessa, C., Laurenza, M., Lauria, A., Torres, E. L., Marafini, M., Massa, M., Massimi, C., Mattei, I., Meneghetti, A., Mengarelli, A., Mirabelli, R., Moggi, A., Montesi, M. C., Morone, M. C., Morrocchi, M., Muraro, S., Murtas, F., Muscato, A., Pastore, A., Pastrone, N., Patera, V., Pennazio, F., Peverini, F., Placidi, P., Pullia, M., Ramello, L., Reidel, C., Ridolfi, R., Rosso, V., Sanelli, C., Sartorelli, G., Sato, O., Savazzi, S., Scavarda, L., Schiavi, A., Schuy, C., Scifoni, E., Sciubba, A., Sécher, A., Selvi, M., Servoli, L., Silvestre, G., Sitta, M., Spighi, R., Spiriti, E., Sportelli, G., Stahl, Achim, Tomassini, S., Tommasino, F., Tioukov, V., Traini, G., Trigilio, A., Valle, S. M., Vanstalle, M., Weber, U., Zarrella, R., Zoccoli, A., Villa, M., Toppi, M, Sarti, A, Alexandrov, A, Alpat, B, Ambrosi, G, Argiro, S, Diaz, RA, Barbanera, M, Bartosik, N, Battistoni, G, Belcari, N, Biondi, S, Bisogni, MG, Bon, M, Bruni, G, Carra, P, Cavanna, F, Cerello, P, Ciarrocchi, E, Clozza, A, Colombi, S, De Lellis, G, De Gregorio, A, Del Guerra, A, De Simoni, M, Di Crescenzo, A, Di Ruzza, B, Donetti, M, Dong, Y, Durante, M, Ferrero, V, Fiandrini, E, Finck, C, Fiorina, E, Fischetti, M, Francesconi, M, Franchini, M, Franciosini, G, Galati, G, Galli, L, Giraudo, G, Hetzel, R, Iarocci, E, Ionica, M, Iuliano, A, Kanxheri, K, Kraan, AC, La Tessa, C, Laurenza, M, Lauria, A, Torres, EL, Marafini, M, Massa, M, Massimi, C, Mattei, I, Meneghetti, A, Mengarelli, A, Mirabelli, R, Moggi, A, Montesi, MC, Morone, MC, Morrocchi, M, Muraro, S, Murtas, F, Muscato, A, Pastore, A, Pastrone, N, Patera, V, Pennazio, F, Peverini, F, Placidi, P, Pullia, M, Ramello, L, Reidel, C, Ridolfi, R, Rosso, V, Sanelli, C, Sartorelli, G, Sato, O, Savazzi, S, Scavarda, L, Schiavi, A, Schuy, C, Scifoni, E, Sciubba, A, Secher, A, Selvi, M, Servoli, L, Silvestre, G, Sitta, M, Spighi, R, Spiriti, E, Sportelli, G, Stahl, A, Tomassini, S, Tommasino, F, Tioukov, V, Traini, G, Trigilio, A, Valle, SM, Vanstalle, M, Weber, U, Zarrella, R, Zoccoli, A, Villa, M, Toppi, M., Sarti, A., Alexandrov, A., Alpat, B., Ambrosi, G., Argirò, S., Diaz, R. A, Barbanera, M., Bartosik, N., Battistoni, G., Belcari, N., Biondi, S., Bisogni, M. G., Bon, M., Bruni, G., Carra, P., Cavanna, F., Cerello, P., Ciarrocchi, E., Clozza, A., Colombi, S., De Lellis, G., De Gregorio, A., Del Guerra, A., De Simoni, M., Di Crescenzo, A., Di Ruzza, B., Donetti, M., Dong, Y., Durante, M., Ferrero, V., Fiandrini, E., Finck, C., Fiorina, E., Fischetti, M., Francesconi, M., Franchini, M., Franciosini, G., Galati, G., Galli, L., Giraudo, G., Hetzel, R., Iarocci, E., Ionica, M., Iuliano, A., Kanxheri, K., Kraan, A. C., La Tessa, C., Laurenza, M., Lauria, A., Torres, E. L, Marafini, M., Massa, M., Massimi, C., Mattei, I., Meneghetti, A., Mengarelli, A., Mirabelli, R., Moggi, A., Montesi, M. C., Morone, M. C., Morrocchi, M., Muraro, S., Murtas, F., Muscato, A., Pastore, A., Pastrone, N., Patera, V., Pennazio, F., Peverini, F., Placidi, P., Pullia, M., Ramello, L., Reidel, C., Ridolfi, R., Rosso, V., Sanelli, C., Sartorelli, G., Sato, O., Savazzi, S., Scavarda, L., Schiavi, A., Schuy, C., Scifoni, E., Sciubba, A., Sécher, A., Selvi, M., Servoli, L., Silvestre, G., Sitta, M., Spighi, R., Spiriti, E., Sportelli, G., Stahl, A., Tomassini, S., Tommasino, F., Tioukov, V., Traini, G., Trigilio, A., Valle, S. M., Vanstalle, M., Weber, U., Zarrella, R., Zoccoli, A., and Villa, M.

Subjects
cross section, Materials Science (miscellaneous), Settore FIS/07, timing detector, Biophysics, General Physics and Astronomy, timing detectors, fragmentation, cross section, timing detectors, particle therapy, space radioprotection, particle therapy, fragmentation, ddc:530, Physical and Theoretical Chemistry, space radioprotection, Mathematical Physics
Abstract

Frontiers in physics 10, 979229 (2022). doi:10.3389/fphy.2022.979229 special issue: "Breakthrough in Particle Therapy: At the Edge of Physics, Biology and Medicine", Published by Frontiers Media, Lausanne

Published
2022

2. Measuring the Impact of Nuclear Interaction in Particle Therapy and in Radio Protection in Space: the FOOT Experiment

Author

Battistoni, G., Toppi, M., Patera, V., Alexandrov, A., De Lellis, G., Di Crescenzo, A., Galati, G., Gentile, V., Iuliano, A., Lauria, A., Montesi, M. C., Tioukov, V., Alpat, B., Ambrosi, G., Fiandrini, E., Kanxheri, K., Placidi, P., Servoli, L., Silvestre, G., Argiro, S., Bartosik, N., Cerello, P., Donetti, M., Ferrero, V., Fiorina, E., Giraudo, G., Lopez Torres, E., Pastrone, N., Ramello, L., Scavarda, L., Sitta, M., Lante, V., Pullia, M., Savazzi, S., Arteche Diaz, R., Dong, Y., Mattei, I., Muraro, S., Valle, S. M., Belcari, N., Bisogni, M. G., Carra, P., Ciarrocchi, E., Del Guerra, A., Francesconi, M., Galli, L., Kraan, A. C., Moggi, A., Morrocchi, M., Raffaelli, F., Rosso, V., Sportelli, G., Zarrella, R., Bellinzona, E., Biondi, S., Bruni, G., Franchini, M., Mengarelli, A., Sartorelli, G., Selvi, M., Spighi, R., Villa, M., Zoccoli, A., Massimi, C., Ridolfi, R., Clozza, A., Iarocci, E., Laurenza, M., Sanelli, C., Sciubba, A., Spiriti, E., Tomassini, S., Fischetti, M., Sarti, A., Schiavi, A., De Simoni, M., Faccini, R., Franciosini, G., Marafini, M., Traini, G., Murtas, F., Colombi, S., Di Ruzza, B., La Tessa, C., Schuy, C., Scifoni, E., Durante, M., Weber, U., Finck, C., Hetzel, R., Stahl, A., Ionica, M., Morone, M. C., Narici, L., Pastore, A., Pennazio, F., Sato, O., Secher, A., Vanstalle, M., Tommasino, F., Battistoni G., Toppi M., Patera V., Alexandrov A., De Lellis G., Di Crescenzo A., Galati G., Gentile V., Iuliano A., Lauria A., Montesi M.C., Tioukov V., Alpat B., Ambrosi G., Fiandrini E., Kanxheri K., Placidi P., Servoli L., Silvestre G., Argiro S., Bartosik N., Cerello P., Donetti M., Ferrero V., Fiorina E., Giraudo G., Lopez Torres E., Pastrone N., Ramello L., Scavarda L., Sitta M., Lante V., Pullia M., Savazzi S., Arteche Diaz R., Dong Y., Mattei I., Muraro S., Valle S.M., Belcari N., Bisogni M.G., Carra P., Ciarrocchi E., Del Guerra A., Francesconi M., Galli L., Kraan A.C., Moggi A., Morrocchi M., Raffaelli F., Rosso V., Sportelli G., Zarrella R., Bellinzona E., Biondi S., Bruni G., Franchini M., Mengarelli A., Sartorelli G., Selvi M., Spighi R., Villa M., Zoccoli A., Massimi C., Ridolfi R., Clozza A., Iarocci E., Laurenza M., Sanelli C., Sciubba A., Spiriti E., Tomassini S., Fischetti M., Sarti A., Schiavi A., De Simoni M., Faccini R., Franciosini G., Marafini M., Traini G., Murtas F., Colombi S., Di Ruzza B., La Tessa C., Schuy C., Scifoni E., Durante M., Weber U., Finck C., Hetzel R., Stahl A., Ionica M., Morone M.C., Narici L., Pastore A., Pennazio F., Sato O., Secher A., Vanstalle M., Tommasino F., Battistoni, G., Toppi, M., Patera, V., De Lellis, G., Di Crescenzo, A., Lauria, A., Montesi, M. C., Durante, M., and Al., Et

Subjects
FOOT, Materials Science (miscellaneous), medicine.medical_treatment, QC1-999, cross section, fragmentation, nuclear interactions, particle therapy, protons RBE, space radioprotection, Biophysics, General Physics and Astronomy, Bragg peak, 01 natural sciences, 030218 nuclear medicine & medical imaging, Nuclear physics, 03 medical and health sciences, 0302 clinical medicine, hadrontherapy, 0103 physical sciences, medicine, ddc:530, Physical and Theoretical Chemistry, 010306 general physics, Nuclear Experiment, Mathematical Physics, Physics, nuclear interaction, protontherapy, Range (particle radiation), Particle therapy, Projectile, business.industry, Equivalent dose, Settore FIS/07, Fragmentation (computing), Charged particle, Radiation protection, business
Abstract

In Charged Particle Therapy (PT) proton or 12C beams are used to treat deep-seated solid tumors exploiting the advantageous characteristics of charged particles energy deposition in matter. For such projectiles, the maximum of the dose is released at the end of the beam range, in the Bragg peak region, where the tumour is located. However, the nuclear interactions of the beam nuclei with the patient tissues can induce the fragmentation of projectiles and/or target nuclei and needs to be carefully taken into account when planning the treatment. In proton treatments, the target fragmentation produces low energy, short range fragments along all the beam path, that deposit a non-negligible dose especially in the first crossed tissues. On the other hand, in treatments performed using 12C, or other (4He or 16O) ions of interest, the main concern is related to the production of long range fragments that can release their dose in the healthy tissues beyond the Bragg peak. Understanding nuclear fragmentation processes is of interest also for radiation protection in human space flight applications, in view of deep space missions. In particular 4He and high-energy charged particles, mainly 12C, 16O, 28Si and 56Fe, provide the main source of absorbed dose in astronauts outside the atmosphere. The nuclear fragmentation properties of the materials used to build the spacecrafts need to be known with high accuracy in order to optimise the shielding against the space radiation. The study of the impact of these processes, which is of interest both for PT and space radioprotection applications, suffers at present from the limited experimental precision achieved on the relevant nuclear cross sections that compromise the reliability of the available computational models. The FOOT (FragmentatiOn Of Target) collaboration, composed of researchers from France, Germany, Italy and Japan, designed an experiment to study these nuclear processes and measure the corresponding fragmentation cross sections. In this work we discuss the physics motivations of FOOT, describing in detail the present detector design and the expected performances, coming from the optimization studies based on accurate FLUKA MC simulations and preliminary beam test results. The measurements planned will be also presented.

Published
2021

3. Performance of the ToF detectors in the FOOT experiment

Author

Traini, G., Alexandrov, A., Alpat, B., Ambrosi, G., Argiro, S., Arteche, D. R., Bartosik, N., Battistoni, G., Belcari, N., Bellinzona, E., Biondi, S., Bisogni, M. G., Bruni, G., Camarlinghi, N., Carra, P., Cerello, P., Ciarrocchi, E., Clozza, A., Colombi, S., de Lellis, G., Del Guerra, A., de Simoni, M., Di Crescenzo, A., Donetti, M., Dong, Y., Durante, M., Emde, M., Faccini, R., Ferrero, V., Ferroni, F., Fiandrini, E., Finck, C., Fiorina, E., Fischetti, M., Francesconi, M., Franchini, M., Franciosini, G., Galati, G., Galli, L., Gentile, V., Giraudo, G., Hetzel, R., Iarocci, E., Ionica, M., Kanxheri, K., Kraan, A. C., Lante, V., Lauria, A., la Tessa, C., Lopez Torres, E., Massimi, C., Mattei, I., Marafini, M., Mengarelli, A., Mirabelli, R., Montesi, M. C., Morone, M. C., Morrocchi, M., Moggi, A., Muraro, S., Narici, L., Pastore, A., Pastrone, N., Patera, V., Pennazio, F., Placidi, P., Pullia, M., Raffaelli, F., Ramello, L., Ridolfi, R., Rosso, V., Rovituso, M., Sanelli, C., Sarti, A., Sartorelli, G., Sato, O., Scavarda, L., Savazzi, A., Schiavi, A., Schuy, C., Scifoni, E., Sciubba, A., Selvi, M., Servoli, L., Secher, A., Silvestre, G., Sitta, M., Spighi, R., Spiriti, E., Sportelli, G., Stahl, A., Tomassini, S., Tommasino, F., Valeri, T., Valle, S. M., Vanstalle, M., Villa, M., Weber, U., Zoccoli, A., Traini G., Alexandrov A., Alpat B., Ambrosi G., Argiro S., Arteche D.R., Bartosik N., Battistoni G., Belcari N., Bellinzona E., Biondi S., Bisogni M.G., Bruni G., Camarlinghi N., Carra P., Cerello P., Ciarrocchi E., Clozza A., Colombi S., de Lellis G., Del Guerra A., de Simoni M., Di Crescenzo A., Donetti M., Dong Y., Durante M., Emde M., Faccini R., Ferrero V., Ferroni F., Fiandrini E., Finck C., Fiorina E., Fischetti M., Francesconi M., Franchini M., Franciosini G., Galati G., Galli L., Gentile V., Giraudo G., Hetzel R., Iarocci E., Ionica M., Kanxheri K., Kraan A.C., Lante V., Lauria A., la Tessa C., Lopez Torres E., Massimi C., Mattei I., Marafini M., Mengarelli A., Mirabelli R., Montesi M.C., Morone M.C., Morrocchi M., Moggi A., Muraro S., Narici L., Pastore A., Pastrone N., Patera V., Pennazio F., Placidi P., Pullia M., Raffaelli F., Ramello L., Ridolfi R., Rosso V., Rovituso M., Sanelli C., Sarti A., Sartorelli G., Sato O., Scavarda L., Savazzi A., Schiavi A., Schuy C., Scifoni E., Sciubba A., Selvi M., Servoli L., Secher A., Silvestre G., Sitta M., Spighi R., Spiriti E., Sportelli G., Stahl A., Tomassini S., Tommasino F., Valeri T., Valle S.M., Vanstalle M., Villa M., Weber U., and Zoccoli A.

Subjects
Particle Therapy, Radio Protection Space, Gantry Cranes, Pencil Beams, Fragmentation cross section, Particle Therapy, Radio Protection Space, Fragmentation cross section, Proton Therapy, ddc:530
Abstract

Fast Timing Applications for nuclear physics and medical imaging, FATA2019, Acireale, Italy, 3 Sep 2019 - 5 Sep 2019; Il nuovo cimento / C 43(1), 1-7 (2020). doi:10.1393/ncc/i2020-20016-5 special issue: "[FATA2019: FAst Timing Applications for nuclear physics and medical imaging, FATA2019, 2019-09-03 - 2019-09-05, Acireale, Italy]", Published by Italian Physical Soc., [S.l.]

Published
2020
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4. A novel detector for 4D tracking in particle therapy.

Author

Data, E.M., Milian, F. Mas, Abujami, M., Bersani, D., Cerello, P., Donetti, M., Mazinani, M. Fadavi, Ferrero, V., Fiorina, E., Garbolino, S., Hosseini, M. Amin, Olivares, D.M. Montalvan, Pennazio, F., Pullia, M., Ranjbar, S., Werner, J.F., Wheadon, R.J., Vignati, A., Cirio, R., and Sacchi, R.

Subjects
*NUCLEAR track detectors, *PARTICLE beams, *ONLINE monitoring systems, *ION beams, *TIME-digital conversion
Abstract

An innovative beam monitor for particle therapy applications was developed to count protons and carbon ions in clinical beams and was integrated with a Time-to-Digital Converter (TDC) to add the measurement of particles' crossing time. The detector exploits strip-segmented planar silicon sensors with an active thickness of a few tens of μm and the front-end electronics is based on a 24-channel ASIC (named ABACUS) for the discrimination of the particles' signals. The proton counting efficiency shows a dependence on the beam energy because of transversal dimension and pile-up effects, whereas an efficiency between 94 and 98 % with lower energy dependence is found for carbon ions. The time measurements with the TDC allow for the study of the time interval between consecutive particles in one strip, which appears to be compatible with the radio-frequency period of the synchrotron. These results indicate that thin silicon sensors and custom front-end readout with high counting rate capability allow for a full 4D tracking of clinical ion beams, opening the way to future technologies for online monitoring systems. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Charge identification of fragments with the emulsion spectrometer of the FOOT experiment

Author

Maria Ionica, Eleuterio Spiriti, P. Carra, N. Bartosik, L. Scavarda, Osamu Sato, Adele Lauria, G. Silvestre, Alberto Del Guerra, Giovanni Ambrosi, Valeri Tioukov, Maria Cristina Montesi, Maria Giuseppina Bisogni, Nadia Pastrone, Alberto Clozza, S. Savazzi, M. Pullia, Alessandra Pastore, Antonio Zoccoli, M. Vanstalle, A. Moggi, E. Bellinzona, V. Lante, Elisa Fiorina, Antonia Di Crescenzo, A. Secher, Ilaria Mattei, Stefano Argiro, Giovanni De Lellis, Antonio Iuliano, Giuliana Galati, Chiara La Tessa, V. Gentile, Gaia Franciosini, Matteo Morrocchi, Luciano Ramello, R. Ridolfi, Giacomo Traini, Silvia Muraro, M. Selvi, Francesco Pennazio, Marco Francesconi, Michela Marafini, Alessio Sarti, A.C. Kraan, Marco Durante, M. Toppi, Pisana Placidi, S. Colombi, F. Raffaelli, C. Finck, Andrey Alexandrov, Christoph Schuy, Valeria Rosso, Adalberto Sciubba, Keida Kanxheri, Behcet Alpat, Nicola Belcari, Leonello Servoli, Sandro Tomassini, Achim Stahl, Angelo Schiavi, Giancarlo Sportelli, Ulrich Weber, Benedetto Di Ruzza, Luca Galli, R. Spighi, E. Iarocci, Martina Laurenza, Roberto Zarrella, Graziano Bruni, Raul Arteche Diaz, S. M. Valle, Y. Dong, Veronica Ferrero, R. Hetzel, Riccardo Faccini, Ernesto Lopez Torres, Silvia Biondi, Giuseppe Battistoni, Mario Sitta, M. Fischetti, Micol De Simoni, E. Scifoni, M. C. Morone, Giuseppe Giraudo, Marco Donetti, Gabriella Sartorelli, Vincenzo Patera, Federica Murtas, Alberto Mengarelli, Francesco Tommasino, E. Fiandrini, Esther Ciarrocchi, Mauro Villa, Matteo Franchini, Piergiorgio Cerello, Cristian Massimi, C. Sanelli, Galati G., Alexandrov A., Alpat B., Ambrosi G., Argiro S., Diaz R.A., Bartosik N., Battistoni G., Belcari N., Bellinzona E., Biondi S., Bisogni M.G., Bruni G., Carra P., Cerello P., Ciarrocchi E., Clozza A., Colombi S., Guerra A.D., Simoni M.D., Di Crescenzo A., Ruzza B.D., Donetti M., Dong Y., Durante M., Faccini R., Ferrero V., Fiandrini E., Finck C., Fiorina E., Fischetti M., Francesconi M., Franchini M., Franciosini G., Galli L., Gentile V., Giraudo G., Hetzel R., Iarocci E., Ionica M., Iuliano A., Kanxheri K., Kraan A.C., Lante V., Tessa C.L., Laurenza M., Lauria A., Torres E.L., Marafini M., Massimi C., Mattei I., Mengarelli A., Moggi A., Montesi M.C., Morone M.C., Morrocchi M., Muraro S., Murtas F., Pastore A., Pastrone N., Patera V., Pennazio F., Placidi P., Pullia M., Raffaelli F., Ramello L., Ridolfi R., Rosso V., Sanelli C., Sarti A., Sartorelli G., Sato O., Savazzi S., Scavarda L., Schiavi A., Schuy C., Scifoni E., Sciubba A., Secher A., Selvi M., Servoli L., Silvestre G., Sitta M., Spighi R., Spiriti E., Sportelli G., Stahl A., Tioukov V., Tomassini S., Tommasino F., Toppi M., Traini G., Valle S.M., Vanstalle M., Villa M., Weber U., Zarrella R., Zoccoli A., De Lellis G., De Lellis, Giovanni, Di Crescenzo, Antonia, Montesi, Maria Cristina, Lauria, Adele, Iuliano, Antonio, and Durante, Marco

Subjects
Materials science, Spectrometer, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, Physics, QC1-999, Settore FIS/07, Analytical chemistry, General Physics and Astronomy, Charge (physics), 01 natural sciences, Fragmentation (mass spectrometry), particle therapy, nuclear emulsion, fragmentation, 0103 physical sciences, Emulsion, ddc:530, Nuclear emulsion, Nuclear Experiment, 010306 general physics
Abstract

Open physics 19(1), 383 - 394 (2021). doi:10.1515/phys-2021-0032, Published by de Gruyter, Berlin

Published
2021

6. THE FOOT EXPERIMENT: FRAGMENTATION MEASUREMENTS IN PARTICLE THERAPY

Author

E. Bellinzona, Nadia Pastrone, Alessandro Pastore, E. López Torres, M. Selvi, L. Alunni Solestizi, Pisana Placidi, E. Iarocci, F. Ferroni, Silvia Muraro, C. La Tessa, M. C. Morone, E. Spiriti, M. Ionica, P. Cerello, Y. Dong, R. Arteche Diaz, A. Zoccoli, A. Secher, Giuliana Galati, V. Lante, Elisa Fiorina, Christoph Schuy, M. De Simoni, M. Vanstalle, Luciano Ramello, K. Kanxheri, Stefano Argiro, S. M. Valle, M. Donetti, M. Garbini, A. C. Kraan, R. Ridolfi, Alberto Mengarelli, Marco Durante, N. Bartosik, A. Moggi, Valeria Rosso, M. Emde, Giacomo Traini, Angelo Schiavi, F. Raffaeli, Niccolò Camarlinghi, M. Pullia, M. Francesconi, G. De Lellis, L. Scavarda, M. Franchini, Mario Sitta, M. Villa, E. Fiandrini, M. Rovituso, Ilaria Mattei, R. Faccini, Alberto Clozza, S. Savazzi, Gabriella Sartorelli, Graziano Bruni, Matteo Morrocchi, Esther Ciarrocchi, Vincenzo Patera, A. Di Crescenzo, A. Sciubba, A. Del Guerra, G. Ambrosi, Valeri Tioukov, M. Fischetti, Veronica Ferrero, E. Scifoni, Francesco Pennazio, Livio Narici, Osamu Sato, Alessio Sarti, Adele Lauria, Francesco Tommasino, S. Colombi, Giancarlo Sportelli, M. G. Bisogni, A. Stahl, V. Gentile, S. Bianucci, R. Mirabelli, Leonello Servoli, U. Weber, Luca Galli, R. Spighi, Nicola Belcari, M. Marafini, A. Embriaco, C. Sanelli, S. Tommasini, C. Finck, Maria Cristina Montesi, P. Carra, G. Silvestre, A. Alexandrov, R. Hetzel, Silvia Biondi, Giuseppe Battistoni, Giuseppe Giraudo, A. Alexandrov, L. Alunni Solestizi, G. Ambrosi, S. Argirò, R. Arteche Diaz, N. Bartosik, G. Battistoni, N. Belcari, E. Bellinzona, S. Bianucci, S. Biondi, M. G. Bisogni, G. Bruni, N. Camarlinghi, P. Carra, P. Cerello, E. Ciarrocchi, A. Clozza, S. Colombi, G. De Lellis, A. Del Guerra, M. De Simoni, A. Di Crescenzo, M. Donetti, Y. Dong, M. Durante, A. Embriaco, M. Emde, R. Faccini, V. Ferrero, F. Ferroni, E. Fiandrini, C. Finck, E. Fiorina, M. Fischetti, M. Francesconi, M. Franchini, G. Galati, L. Galli, M. Garbini, V. Gentile, G. Giraudo, R. Hetzel, E. Iarocci, M. Ionica, K. Kanxheri, A. C. Kraan, V. Lante, A. Lauria, C. La Tessa, E. Lopez Torres, M. Marafini, I. Mattei, A. Mengarelli, R. Mirabelli, A. Moggi, M. C. Montesi, M. C. Morone, M. Morrocchi, S. Muraro, L. Narici, A. Pastore, N. Pastrone, V. Patera, F. Pennazio, P. Placidi, M. Pullia, F. Raffaeli, L. Ramello, R. Ridolfi, V. Rosso, M. Rovituso, C. Sanelli, A. Sarti, G. Sartorelli, O. Sato, S. Savazzi, L. Scavarda, A. Schiavi, C. Schuy, E. Scifoni, A. Sciubba, A. Sécher, M. Selvi, L. Servoli, G. Silvestre, M. Sitta, R. Spighi, E. Spiriti, G. Sportelli, A. Stahl, V. Tioukov, S. Tommasini, F. Tommasino, G. Traini, S. M. Valle, M. Vanstalle, M. Villa, U. Webe, A. Zoccoli, Alexandrov, A., Alunni Solestizi, L., Ambrosi, G., Argirò, S., Arteche Diaz, R., Bartosik, N., Battistoni, G., Belcari, N., Bellinzona, E., Bianucci, S., Biondi, S., Bisogni, M. G., Bruni, G., Camarlinghi, N., Carra, P., Cerello, P., Ciarrocchi, E., Clozza, A., Colombi, S., De Lellis, G., Del Guerra, A., De Simoni, M., Di Crescenzo, A., Donetti, M., Dong, Y., Durante, M., Embriaco, A., Emde, M., Faccini, R., Ferrero, V., Ferroni, F., Fiandrini, E., Finck, C., Fiorina, E., Fischetti, M., Francesconi, M., Franchini, M., Galati, G., Galli, L., Garbini, M., Gentile, V., Giraudo, G., Hetzel, R., Iarocci, E., Ionica, M., Kanxheri, K., Kraan, A. C., Lante, V., Lauria, A., La Tessa, C., Lopez Torres, E., Marafini, M., Mattei, I., Mengarelli, A., Mirabelli, R., Moggi, A., Montesi, M. C., Morone, M. C., Morrocchi, M., Muraro, S., Narici, L., Pastore, A., Pastrone, N., Patera, V., Pennazio, F., Placidi, P., Pullia, M., Raffaeli, F., Ramello, L., Ridolfi, R., Rosso, V., Rovituso, M., Sanelli, C., Sarti, A., Sartorelli, G., Sato, O., Savazzi, S., Scavarda, L., Schiavi, A., Schuy, C., Scifoni, E., Sciubba, A., Sécher, A., Selvi, M., Servoli, L., Silvestre, G., Sitta, M., Spighi, R., Spiriti, E., Sportelli, G., Stahl, A., Tioukov, V., Tommasini, S., Tommasino, F., Traini, G., Valle, S. M., Vanstalle, M., Villa, M., Weber, U., and Zoccoli, A.

Subjects
Nuclear physics, Particle therapy, Materials science, Physics::Instrumentation and Detectors, medicine.medical_treatment, Quantitative Biology::Tissues and Organs, Physics::Medical Physics, Media Technology, medicine, Fragmentation (computing), Nuclear Experiment, fragmentation, hadrotherapy, cross section, Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
Abstract

Charged Particle Therapy (CPT) is a powerful radiotherapy technique for the treatment of deep-seated tumours characterized by a large dose released in the Bragg peak area (corresponding to the tumour region) and a small dose delivered to the surrounding healthy tissues. The precise measurement of the fragments produced in the nuclear interactions of charged particle beams with patient tissues is a crucial task to improve the clinical treatment plans. The FOOT (FragmentatiOn Of Target) experiment is an international project, funded by the Istituto Nazionale di Fisica Nucleare (INFN), aimed to study the dose released by the tissues and particle beams fragmentation. The target (16O, 12C) fragmentation induced by 150-400 MeV/n proton beams will be studied via the inverse kinematic approach, where 16O and 12C therapeutic beams collide on graphite and hydrocarbon target to provide the cross section on Hydrogen. A table-top detector is being developed and it includes a drift chamber as a beam monitor upstream of the target to measure the beam direction, a magnetic spectrometer based on silicon pixel and strip detectors, a scintillating crystal calorimeter able to stop the heavier produced fragments, and a ΔE detector, with TOF capability, for the particle identification. A setup based on the concept of the “Emulsion Cloud Chamber”, coupled with the interaction region of the electronic FOOT setup, will complement the physics program by measuring lighter charged fragments to extend the angular acceptance up to about 70 degrees. In this work, the experimental design and the requirements of the FOOT experiment will be discussed and preliminary results on the emulsion spectrometer tests will be presented.

Published
2019

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