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Start Over Author "Bat, Taha" Topic paroxysmal hemoglobinuria
2 results on '"Bat, Taha"'

1. Ahemolytic PNH (white cell PNH): Clinical features and implications of a distinct phenotype of paroxysmal nocturnal haemoglobinuria.

Author

Tombul, Zehra, Bahaj, Waled, Ozturk, Merve, Patel, Bhavisha, Toprak, Ahmet, Ibrahim, Ibrahim, Chen, Weina, Fuda, Franklin, Ogbue, Olisaemeka D., Gurnari, Carmelo, Parker, Charles, Young, Neal S., Maciejewski, Jaroslaw P., Duran, Munevver, and Bat, Taha

Subjects
PAROXYSMAL hemoglobinuria, LEUCOCYTES, PHENOTYPES, NATURAL history
Abstract

The article explores a specific type of paroxysmal nocturnal haemoglobinuria (PNH) known as ahemolytic PNH or white cell PNH. Unlike typical PNH, this subtype does not exhibit signs of hemolysis but is characterized by bone marrow failure and thrombophilia. The document suggests that this subtype may be caused by a PIGA mutation in a committed progenitor cell rather than a stem cell. The authors recommend considering screening for ahemolytic PNH in cases of thromboembolic events and bone marrow failure without hemolysis. [Extracted from the article]

Published
2024
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