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Purpose: There is a need to create objective and reproducible tool for assessing the quality of infant movements. It's substantially important to detect movement disorders in infants as early as possible. The study aimed to evaluate the reproducibility of kinesiological measurements of spontaneous movements performed by 51 infants (aged 6 to 15 weeks) recorded three times for two consecutive days using OSESEC computer analysis algorithms by determining numerical values of parameters, i.e., speed, acceleration, direction, and movement trajectory. Methods: The study group consisted of 51 infants. The diagnostic method of Prechtl was used for qualitative assessment. The quantitative assessment was based on the use of a OSESEC system. Numerical values for all movement parameters were determined, and the data obtained in the study were used for statistical analysis. Results: Analysis including movement parameter values on three consecutive recordings for the same infant revealed no statistically significant differences in location (p = 0.073), range (p = 0.557), shape (p = 0.289), mean acceleration (p = 0.124) and mean speed (p = 0.767). This confirms the reproducibility of measurements of the proposed parameters of the objectification of spontaneous infant movements. Conclusions: The interpretability and accuracy of the presented parameters were proved. All parameters estimation is fully automated. Further research and testing requires a larger study group to create an objective diagnostic device for infants. [ABSTRACT FROM AUTHOR]

Over the last few decades, high-frequency ultrasound has found multiple applications in various diagnostic fields. The fast development of this imaging technique opens up new diagnostic paths in dermatology, allergology, cosmetology, and aesthetic medicine. In this paper, being the first in this area, we discuss the usability of HFUS in anti-aging skin therapy assessment. The fully automated algorithm combining high-quality image selection and entry echo layer segmentation steps followed by the dermal parameters estimation enables qualitative and quantitative evaluation of the effectiveness of anti-aging products. Considering the parameters of subcutaneous layers, the proposed framework provides a reliable tool for TCA-peel therapy assessment; however, it can be successfully applied to other skin-condition-related problems. In this randomized controlled clinical trial, forty-six postmenopausal women were randomly assigned to the experimental and control groups. Women were treated four times at one-week intervals and applied skin cream daily between visits. The three month follow-up study enables measurement of the long-term effect of the therapy. According to the results, the TCA-based therapy increased epidermal (entry echo layer) thickness, indicating that the thinning process has slowed down and the skin's condition has improved. An interesting outcome is the obtained growth in the intensity of the upper dermis in the experimental group, which might suggest a reduced photo-aging effect of TCA-peel and increased water content. The same conclusions connected with the anti-aging effect of TCA-peel can be drawn by observing the parameters describing the contribution of low and medium-intensity pixels in the upper dermis. The decreased share of low-intensity pixels and increased share of medium-intensity pixels in the upper dermis suggest a significant increase in local protein synthesis. [ABSTRACT FROM AUTHOR]

Purpose: In clinical practice, motor development in infants is assessed subjectively. Many researchers propose objective methods, which have numerous limitations, by attaching markers or sensors to the child's limbs. The purpose of this study is to attempt to develop objectified numerical indices to describe the limb movements of infants without interfering with spontaneous activity. Methods: 20-minute video recordings of three infants' movements who were purposively selected from 51 subjects were included in the study. The procedure of automatic calculation of head position time in 3 positions was applied. Movement features were determined to allow for the delineation of coefficients describing the movement in numerical values. Results: Presented parameters describe three infant's movement aspects: quality (strength), distribution of postural tonus and asymmetry in relation to head position, described as four independent values. Estimated parameters variability over time was weighted up according to expert observations. The presented method is a direct reflection of infants' observation, currently performed by highly educated and experienced therapists. Conclusions: The interpretability and usefulness of the presented parameters were proved. All parameters estimation is fully automated. The conducted research is a prelude to future work related to creating an objective and repeatable tool, initially monitoring and ultimately supporting early diagnosis for differentiating normal and abnormal motor development. [ABSTRACT FROM AUTHOR]