Search

Your search keyword '"Lykova NI"' showing total 2 results
Start Over Author "Lykova NI" Topic oxyuriasis
2 results on '"Lykova NI"'

1. [A comparative study of the efficacy of medamine, albendazole and embovin in models of syphaciasis and aspiculariasis].

Author

Lykova NI, Veretennikova NL, and Lebedeva MN

Subjects
Animals, Drug Evaluation, Preclinical, Larva, Mice, Oxyuriasis parasitology, Time Factors, Albendazole therapeutic use, Antinematodal Agents therapeutic use, Benzimidazoles therapeutic use, Carbamates, Disease Models, Animal, Oxyuriasis drug therapy, Oxyuroidea, Pyrantel Pamoate therapeutic use
Abstract

The study covers the study of three antinematodal agents: the original national drug medamine with albendazole and embovin (pyrathel pamoate), which have been reproduced at the E. I. Martsinovskiĭ Institute of Medical Parasitology and Tropical Medicine, with murine Syphacia obvelata and Aspiculuris tetraptera infection models. The quantitative parameters of the anthelmintic action of medamine, albendazole and embivin were comparatively defined for the first time.

Published
1994

2. [The efficacy of a new Russian preparation metiazol in experimental aspiculariasis in mice].

Author

Lykova NI, Veretennikova NL, Lebedeva MN, Timonov EV, and D'iachenko GN

Subjects
Albendazole toxicity, Animals, Antinematodal Agents therapeutic use, Antinematodal Agents toxicity, Benzimidazoles therapeutic use, Benzimidazoles toxicity, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Lethal Dose 50, Mice, Pyrantel Pamoate therapeutic use, Pyrantel Pamoate toxicity, Albendazole therapeutic use, Carbamates, Oxyuriasis drug therapy
Abstract

The efficacy of metiasole, a new Russian analog of albendasole, reproduced at the E. I. Martsinovskiĭ Institute of Medical Parasitology and Tropical Medicine, was studied in mice with Aspiculuris tetraptera invasion. Metiasole efficacy and acute toxicity were comparable to those of embovin and superior to those of medamin. Relationship between the drug efficacy and its doses and number of injections was analyzed.

Published
1993

Catalog

Books, media, physical & digital resources
See catalog results