56 results on '"Eugene T. Ek"'
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2. Medial Femoral Condyle Corticoperiosteal Flap for Failed Total Wrist Fusions
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Richard Tee, Jason N. Harvey, Stephen K. Tham, and Eugene T. Ek
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Orthopedics and Sports Medicine ,Surgery - Abstract
Background Recalcitrant nonunion following total wrist arthrodesis is a rare but challenging problem. Most commonly, in the setting of failed fusion after multiple attempts of refixation and cancellous bone grafting, the underlying cause for the failure is invariably multifactorial and is often associated with a range of host issues in addition to poor local soft-tissue and bony vascularity. The vascularized medial femoral condyle corticoperiosteal (MFC-CP) flap has been shown to be a viable option in a variety of similar settings, which provides vascularity and rich osteogenic progenitor cells to a nonunion site, with relatively low morbidity. While its utility has been described for many other anatomical locations throughout the body, its use for the treatment of failed total wrist fusions has not been previously described in detail in the literature. Methods In this article, we outline in detail the surgical technique for MFC-CP flap for the management of recalcitrant aseptic nonunions following failed total wrist arthrodesis. We discuss indications and contraindications, pearls and pitfalls, and potential complications of this technique. Results Two illustrative cases are presented of patients with recalcitrant nonunions following multiple failed total wrist fusions. Conclusion When all avenues have been exhausted, a free vascularized corticoperiosteal flap from the MFC is a sound alternative solution to achieve union, especially when biological healing has been compromised. We have been able to achieve good clinical outcomes and reliable fusion in this difficult patient population.
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- 2023
3. Biomechanical Comparison of Distal Biceps Tendon Repair Techniques: Extracortical Single-Button Inlay Fixation Versus Intracortical Double-Button Onlay Anatomic Footprint Fixation
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Lukas Ernstbrunner, Mitchell Almond, Harshi S. Rupasinghe, Olivia I. Jo, Robert M. Zbeda, David C. Ackland, and Eugene T. Ek
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Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine - Abstract
Background: Extracortical single-button (SB) inlay repair is a commonly used distal biceps tendon technique. However, complications (eg, neurovascular injury) and nonanatomic repairs have led to the development of intracortical fixation techniques. Purpose: To compare the biomechanical stability of extracortical SB repair with an anatomic intracortical double-button (DB) repair technique. Study Design: Controlled laboratory study. Methods: The distal biceps tendon was transected in 18 cadaveric elbows from 9 donors. One elbow of each donor was randomly assigned to the extracortical SB or anatomic DB group. Both groups were cyclically loaded with 60 N over 1000 cycles between 90° of flexion and full extension. The elbow was then fixed in 90° of flexion and the repair construct loaded to failure. Gap formation and construct stiffness during cyclic loading and ultimate load to failure were analyzed. Results: When compared with the extracortical SB technique after 1000 cycles, the anatomic DB technique showed significantly less gap formation (mean ± SD, 2.7 ± 0.8 vs 1.5 ± 0.9 mm; P = .017) and significantly more construct stiffness (87.4 ± 32.7 vs 119.9 ± 31.6 N/mm; P = .023). Ultimate load to failure was not significantly different between the groups (277 ± 93 vs 285 ± 135 N; P = .859). The failure mode in the anatomic DB group was significantly different from that of the extracortical SB technique ( P = .002) and was due to fracture avulsion of the cortical button in 7 of 9 specimens (vs none in the SB group). Conclusion: Our study shows that the intracortical DB technique produces equivalent or superior biomechanical performance to that of the SB technique. The DB technique may offer a clinically viable alternative to the SB repair technique. Clinical Relevance: This study suggests, at worst, an equivalent and, at best, a superior biomechanical performance of intracortical anatomic DB footprint repair at the time of surgery. However, the mode of failure suggests that this technique should not be used in patients with poor bone quality.
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- 2023
4. Stress reactions and fractures around the elbow in athletes
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Greg Hoy, Godefroy Brais, Tim Wood, Eugene T. Ek, and Andrew Phillip Mcbride
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medicine.medical_specialty ,Coronoid process of the ulna ,Fractures, Stress ,Elbow ,Physical Therapy, Sports Therapy and Rehabilitation ,Fractures, Bone ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Elbow Joint ,medicine ,Humans ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,Stress fractures ,biology ,business.industry ,Athletes ,Ulna ,030229 sport sciences ,medicine.disease ,biology.organism_classification ,medicine.anatomical_structure ,Athletic Injuries ,Upper limb ,Elbow Injuries ,Epicondyle ,business ,human activities ,Throwing - Abstract
Stress fractures of the upper limb affect athletes from a wide range of sports. Athletes involved in throwing sports are particularly susceptible along with athletes from sports involving high repetitive and compressive loads such as gymnastics. Diagnosis can be made from clinical history, examination and radiography in some cases however MRI imaging is often required for definitive diagnosis. The mainstay of management is rest and activity modification however advanced pathology often requires surgical management for successful resolution and return to play. In the elbow, the bones susceptible to excessive stress in sport are the distal humerus, the olecranon process of the ulna, the coronoid process of the ulna, the sublime tubercle and the radial head. In immature patients, medial epicondyle apophysis is the most common location. The article presents a narrative review of the literature.
- Published
- 2021
5. Biomechanical analysis of plating techniques for unstable lateral clavicle fractures with coracoclavicular ligament disruption (Neer Type-IIB)
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Olivia I. Jo, Mitchell Almond, Harshi S. Rupansinghe, David C. Ackland, Lukas Ernstbrunner, and Eugene T. Ek
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Orthopedics and Sports Medicine ,Surgery ,General Medicine - Abstract
Neer Type-IIB lateral clavicle fractures are inherently unstable fractures with associated disruption of the coracoclavicular (CC) ligaments. Due to the high rate of non-union and malunion, surgical fixation is recommended, however no consensus has been reached regarding the optimal fixation method. A new plating technique using a superior lateral locking plate with antero-posterior (AP) locking screws, resulting in orthogonal fixation in the lateral fragment has been designed to enhance stability and reduce implant failure. The purpose of this study was to biomechanically compare three different clavicle plating constructs within a fresh-frozen human cadaveric shoulder model.24 fresh-frozen cadaveric shoulders were randomized into three groups (n=8 specimens). Group 1: lateral locking plate only (Medartis Aptus Superior Lateral Plate); Group 2: lateral locking plate with CC stabilization (No. 2 FiberWire); and Group 3: lateral locking plate with two AP locking screws stabilizing the lateral fragment. All specimens were subject to cyclic loading of 70N for 500 cycles. Data was analyzed for gap formation after cyclic loading, construct stiffness and ultimate load to failure, defined by a marked decrease in the load displacement curve.After 500 cycles, there was no statistically significant difference between the three groups in gap-formation (p = 0.179). No specimen (0/24) failed during cyclic loading. Ultimate load to failure was significantly higher in Group 3 compared to Group 1 (286N vs. 167N; p = 0.022), but not to Group 2 (286N vs. 246N; p = 0.604). There were no statistically significant differences in stiffness (Group 1: 504N/mm; Group 2: 564N/mm; Group 3: 512N/mm; p = 0.712). Peri-implant fracture was the primary mode of failure for all three groups, with Group 3 demonstrating the lowest rate of peri-implant fractures (Group 1: 6/8; Group 2: 7/8, Group 3: 4/8; p = 0.243).Biomechanical evaluation of the clavicle plating techniques showed effective fixation across all specimens at 500 cycles. The lateral locking plate with orthogonal AP locking screw fixation in the lateral fragment demonstrated the greatest ultimate failure load, followed by the lateral locking plate with CC stabilization. This new plating technique showed compatible stiffness and gap formation when compared to conventional lateral locking plates as well as plates with CC fixation. The use of orthogonal screw fixation in the distal fragment may negate against the need for CC stabilization in these types of fractures, thus minimizing surgical dissection around the coracoid and potential complications.
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- 2022
6. Arthroscopic-Assisted Lower Trapezius Tendon Transfer for Massive Irreparable Posterosuperior Rotator Cuff Tears Using an Achilles Tendon-Bone Allograft
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Timothy Lording, Eugene T. Ek, and Andrew P. McBride
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Orthopedic surgery ,musculoskeletal diseases ,030222 orthopedics ,medicine.medical_specialty ,Achilles tendon ,Bone allograft ,business.industry ,medicine.medical_treatment ,030229 sport sciences ,musculoskeletal system ,Tendon ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Tendon transfer ,Technical Note ,medicine ,Tears ,Orthopedics and Sports Medicine ,Rotator cuff ,Humerus ,business ,RD701-811 ,Fixation (histology) - Abstract
The lower trapezius tendon (LTT) transfer has been described for the management of irreparable posterosuperior rotator cuff tears. Here we describe our technique of an arthroscopic-assisted LTT transfer using an Achilles tendon-bone allograft. This technique allows for augmentation of the tendon transfer using an Achilles tendon allograft while also keeping the calcaneal bone insertion, which allows for added bony fixation into the humerus and also minimizing the risk of the ''killer turn'' phenomenon at the aperture of fixation.
- Published
- 2020
7. Clinical Outcomes of Double-Screw Fixation with Autologous Bone Grafting for Unstable Scaphoid Delayed or Nonunions with Cavitary Bone Loss
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Gayan Padmasekara, Paul R. Johnson, Eugene T. Ek, and Carmel M. Bohan
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030222 orthopedics ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Nonunion ,Scaphoid fracture ,Bone grafting ,Wrist ,medicine.disease ,Asymptomatic ,Surgery ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,medicine.anatomical_structure ,Medicine ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,medicine.symptom ,business ,Range of motion ,Cancellous bone - Abstract
Objective This study reports on the clinical outcomes of double screw fixation with autologous cancellous bone grafting and early active range of motion for delayed and nonunited scaphoid waist fractures with cavitary segmental bone loss. Patients and Methods Twenty-one consecutive patients underwent fixation using two 2.2 mm antegrade headless compression screws with autologous distal radius cancellous bone graft. Postoperatively, patients were allowed early active motion with a resting splint until union was achieved. Patients were reviewed radiologically and clinically to assess for fracture union, complications, residual pain, wrist function, and return to work and recreational activities. Results All but one patient was male, and the mean age was 23 years (range, 15–38 years). The average time from initial injury was 16 months (range, 3–144 months). Nineteen of 21 (90.5%) patients achieved union at a mean of 2.8 months (range, 1.4–9.2 months). Of the patients who failed, one underwent revision surgery with vascularized bone grafting at 10.6 months. The other patient refused further intervention as he was asymptomatic. Conclusion Double-screw fixation with bone grafting and early active range of motion is a safe and effective technique for management of delayed and nonunited unstable scaphoid fractures with cavitary bone loss. This potentially allows for earlier return to function, without compromise to union rates. Level of Evidence This is a Level IV, retrospective case series study.
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- 2020
8. Arthroscopic Knotless Repair of Complete Full-Thickness Tears of the Subscapularis Tendon Through a Single Portal
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Paul Borbas, Michael C. Perret, and Eugene T. Ek
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Orthopedic surgery ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,030229 sport sciences ,Subscapularis tendon ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,Technical Note ,Medicine ,Tears ,Open repair ,Orthopedics and Sports Medicine ,Full thickness ,Lesser Tuberosity ,business ,RD701-811 ,Suture anchors - Abstract
Arthroscopic repair of subscapularis tendon tears has shown to be a reliable and reproducible technique and is now considered the gold standard method over open repair. However, most arthroscopic techniques use several working portals and the procedure can be technically challenging and time-consuming, especially when knot-tying is required and when multiple anchors are used. Recently, single-portal knotless techniques have been popularized for upper-third lesions (e.g. Lafosse type 1 or 2 tears). Here, we describe a technique of repairing complete tears of the subscapularis tendon (Lafosse type 3 and 4) using knotless suture anchors through a single portal. This technique is quick and allows a safe anatomic footprint repair to the lesser tuberosity.
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- 2020
9. Medial Femoral Trochlea Graft for Scaphoid Waist Nonunion: A Case Report and Review of the Literature
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Eugene T. Ek, Bruno E. Crepaldi, Stephen K.Y. Tham, and Cameron Keating
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030222 orthopedics ,medicine.medical_specialty ,business.industry ,Scaphoid nonunion ,Nonunion ,Scaphoid fracture ,030230 surgery ,Femoral trochlea ,Articular surface ,medicine.disease ,Degenerative change ,Surgery ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,medicine ,Orthopedics and Sports Medicine ,Scaphoid waist ,business - Abstract
The medial femoral trochlea (MFT) of the knee is a donor site for convex osteochondral vascularized bone that has been used for the salvage of fractures of the proximal pole of the scaphoid. Chronic nonunited fractures of the scaphoid may lead to a sequence of degenerative change often referred to as scaphoid nonunion advance collapse. The vascularized MFT osteochondral graft has been reported as a salvage procedure for fractures of the proximal pole of the scaphoid, in situations where fixation is not an option. In this “Special review,” we describe the technique of free vascularized MFT graft in a case in which the nonunited scaphoid fracture was associated with segmental loss of the articular surface of the scaphoid waist. Given the likely progression of arthritis, if left untreated, we elected to treat this by replacing the lost articular surface using a vascularized intercalary osteochondral MFT graft between the nonunited scaphoid segments.
- Published
- 2019
10. A new all-suture tension band tape fixation technique for simple olecranon fractures versus conventional tension band wire fixation: a comparative biomechanics study
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Lukas Ernstbrunner, Harshi Sandeepa Rupasinghe, Mitchell Almond, Olivia I. Jo, Robert M. Zbeda, Andrew Oppy, Thomas Treseder, Christopher Pullen, Eugene T. Ek, and David C. Ackland
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Fracture Fixation, Internal ,Fractures, Bone ,Sutures ,Humans ,Orthopedics and Sports Medicine ,Surgery ,General Medicine ,Olecranon Process ,Ulna Fractures ,Biomechanical Phenomena ,Bone Wires - Abstract
Simple transverse or short oblique olecranon fractures without articular comminution are classified as Mayo type IIA fractures and are typically treated with a tension band wire construct. Because of the high reoperation rates, frequently because of prominent hardware, all-suture tension band constructs have been introduced. It was the purpose to compare the biomechanical performance of conventional tension band wire fixation with a new all-suture tension band tape fixation for simple olecranon fractures.Mayo type IIA olecranon fractures were created in 20 cadaveric elbows from 10 donors. One elbow of each donor was randomly assigned to the tension band wire technique (group TBW) or tension band tape (Arthrex, 1.3-mm SutureTape) technique (group TBT). Both groups were cyclically loaded with 500 N over 500 cycles, after which a uniaxial displacement was performed to evaluate load to failure. Data were analyzed for gap formation after cyclic loading, construct stiffness, and ultimate load to failure, where failure was defined as fracture gap formation greater than 4.0 mm.There was no significant difference in gap formation after 500 cycles between the TBW (1.8 mm ± 1.3 mm) and the TBT (1.9 mm ± 1.1 mm) groups (P = .854). The TBT showed a tendency toward greater construct stiffness compared with the TBW construct (mean difference: 142 N/mm; P = .053). Ultimate load to failure was not significantly different comparing both groups (TBW: 1138 N ± 286 N vs. TBT: 1126 N ± 272 N; P = .928). In both groups, all repairs failed because of4.0-mm gap formation at the fracture site and none because of tension band construct breakage.Our study shows that the TBT technique produces equivalent or superior biomechanical performance to the TBW for simple olecranon fractures. The TBT approach reduces the risk of hardware prominence and as a result mitigates against the need for hardware removal. The TBT technique offers a clinically viable alternative to TBW.
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- 2021
11. Role of Tranexamic Acid in Arthroscopic Osteocapsular Release of the Elbow for Degenerative Arthritis
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Eugene T. Ek, Kemble K. Wang, Carmel M. Bohan, Nicholas J. Goulding, and Richard P. Jamieson
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Orthopedics and Sports Medicine - Abstract
Background Minimizing intra-articular bleeding and swelling is crucial in preventing the development of stiffness around the elbow. Tranexamic acid (TXA) has been shown to be an effective adjunct in reducing perioperative bleeding after surgery. Purpose: To determine the effect of intravenous (IV) TXA on postoperative drain tube output in arthroscopic osteocapsular release of the elbow for primary degenerative arthritis. Study Design: Cohort study; Level of evidence, 3. Methods: The authors performed a retrospective cohort study of 83 consecutive patients with primary degenerative elbow arthritis who underwent an arthroscopic osteocapsular release between 2015 and 2018. They organized patients into a no-TXA group (control) and a group that was given 1.0 g of IV TXA before tourniquet release. The primary outcome measure was drain tube output, and secondary outcome measures included postoperative day 1 pain levels on a visual analog scale and early range of motion at 8 weeks. Differences between groups were analyzed using 1-way analysis of variance, the Mann-Whitney U test, or the Fisher exact test. Results: There were 43 patients in the no-TXA group and 40 patients in the TXA group. Administration of IV TXA resulted in a 51% decrease in mean intra-articular bleeding for the TXA group, as measured via drain tube output (88.8 ± 80.5 mL [no-TXA] vs 43.4 ± 52.4 mL [TXA]; P = .0016). In both groups, there were significant increases in elbow arc of motion when compared with preoperative measurements. There were no between-group differences in early range of motion (129.7° ± 12.4° [no-TXA] vs 131.7° ± 9.2° [TXA]; P = .549) or postoperative pain (1.9 ± 2.2 [no-TXA] vs 1.5 ± 1.7 [TXA]; P = .89). Conclusion: In this study, IV TXA significantly reduced postoperative intra-articular bleeding in patients who underwent arthroscopic osteocapsular release of the elbow for primary degenerative arthritis. However, there were no differences in postoperative range of motion or pain between patients who received TXA and controls.
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- 2021
12. The Scapholunate Dilemma
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Stephen K.Y. Tham and Eugene T. Ek
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Dilemma ,Psychoanalysis ,business.industry ,Medicine ,Orthopedics and Sports Medicine ,Surgery ,business - Published
- 2021
13. Characterization of the Proximal Long Head of Biceps Tendon Anatomy Using Magnetic Resonance Imaging: Implications for Biceps Tenodesis
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Nada Richards, Andrew H. Rotstein, Eugene T. Ek, Andrew Hardidge, Ayla D Wood, Jennifer N Flynn, and Andrew J Philpott
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,Tenodesis ,Physical Therapy, Sports Therapy and Rehabilitation ,Biceps ,Tendons ,03 medical and health sciences ,Arthroscopy ,Young Adult ,0302 clinical medicine ,Medicine ,Musculotendinous junction ,Humans ,Orthopedics and Sports Medicine ,Muscle, Skeletal ,030222 orthopedics ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,030229 sport sciences ,Anatomy ,Middle Aged ,Magnetic Resonance Imaging ,Orthopedic surgery ,Arm ,Female ,business ,Biceps tendon ,Tendon pathology - Abstract
Background: Biceps tenodesis is a common treatment for proximal long head of biceps (LHB) tendon pathology. To maintain biceps strength and contour and minimize cramping, restoration of muscle-length tension and appropriate positioning of the tenodesis is key. Little is known about the biceps musculotendinous junction (MTJ) anatomy, especially in relation to the overlying pectoralis major tendon (PMT), which is a commonly used landmark for tenodesis positioning. Purpose: To characterize the in vivo topographic anatomy of the LHB tendon, in particular the MTJ relative to the PMT, using a novel axial proton-density magnetic resonance imaging (MRI) sequence. Study Design: Descriptive laboratory study. Methods: In total, 45 patients having a shoulder MRI for symptoms unrelated to their biceps tendon or rotator cuff were prospectively recruited. There were 33 men and 12 women, with a mean age of 37 ± 13 years (range, 18-59 years). All patients underwent routine shoulder MRI scans with an additional axial proton density sequence examining the LHB tendon and its MTJ. Three independent observers reviewed each MRI scan, and measurements were obtained for (1) MTJ length, (2) the distance between the proximal MTJ and the superior border of the PMT (MTJ-S), (3) the distance between the distal MTJ to the inferior border of the PMT, and (4) the width of the PMT. Results: The average position of the MTJ-S was 5.9 ± 10.8 mm distal to the superior border of the PMT. The mean MTJ length was 32.5 ± 8.3 mm and the width of the PMT was 28.0 ± 7.3 mm. We found no significant correlation between patient age, height, sex, or body mass index and any of the biceps measurements. We observed wide variability of the MTJ-S position and identified 3 distinct types of biceps MTJ: type 1, MTJ-S above the PMT; type 2, MTJ-S between 0 and 10 mm below the superior border of the PMT; and type 3, MTJ-S >10 mm distal to the superior PMT. Conclusion: In this study, the in vivo anatomy of the LHB tendon is characterized relative to the PMT using a novel MRI sequence. The results demonstrate wide variability in the position of the MTJ relative to the PMT, which can be classified into 3 distinct subtypes or zones relative to the superior border of the PMT. Understanding this potentially allows for accurate and anatomic placement of the biceps tendon for tenodesis. Clinical Relevance: To our knowledge, this is the first study to radiologically analyze the in vivo topographic anatomy of the LHB tendon and its MTJ. The results of this study provide more detailed understanding of the variability of the biceps MTJ, thus allowing for more accurate placement of the biceps tendon during tenodesis.
- Published
- 2020
14. Surgical Repair of Triangular Fibrocartilage Complex Tears: A Systematic Review
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Stephen K.Y. Tham, Kary Suen, Eugene T. Ek, and Edward H. Liu
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Surgical repair ,medicine.medical_specialty ,business.industry ,Triangular fibrocartilage ,Surgery ,Grip strength ,medicine.anatomical_structure ,Suture (anatomy) ,Dash ,Orthopedic surgery ,Medicine ,Tears ,Orthopedics and Sports Medicine ,business ,Triangular Fibrocartilage Complex - Abstract
Objective This study systematically reviews the outcomes of surgical repair of triangular fibrocartilage complex (TFCC) tears. Existing surgical techniques include capsular sutures, suture anchors, and transosseous sutures. However, there is still no consensus as to which is the most reliable method for ulnar-sided peripheral and foveal TFCC tears. Methods A systematic review of MEDLINE and EMBASE was performed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The focus was on traumatic Palmer 1B ulna-sided tears. Twenty-seven studies were included, including three comparative cohort studies. Results There was improvement in all functional outcome measures after repair of TFCC tears. The outcomes following peripheral and foveal repairs were good overall: Mayo Modified Wrist Evaluation (MMWE) score of 80.1 and 85.1, Disabilities of the Arm, Shoulder and Hand (DASH) score of 15.7 and 15.8, grip strength of 80.3 and 92.7% (of the nonoperated hand), and pain intensity score of 2.1 and 1.7, respectively. For peripheral tears, transosseous suture technique achieved better outcomes compared with capsular sutures in terms of grip strength, pain, Patient-Rated Wrist Evaluation (PRWE), and DASH scores (grip 85.8 vs. 77.7%; pain 1.5 vs. 2.2; PRWE 11.6 vs. 15.8; DASH 14.4 vs. 16.1). For foveal tears, transosseous sutures achieved overall better functional outcomes compared with suture anchors (MMWE 85.4 vs. 84.9, DASH 10.9 vs. 20.6, pain score 1.3 vs. 2.1), but did report slightly lower grip strength than the group with suture anchors (90.2 vs. 96.2%). Arthroscopic techniques achieved overall better outcomes compared with open repair technique. Conclusion Current evidence demonstrates that TFCC repair achieves good clinical outcomes, with low complication rates. Level of Evidence This is a Level IV, therapeutic study.
- Published
- 2020
15. Single versus dual orthogonal plating for comminuted midshaft clavicle fractures: a biomechanics study
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David C. Ackland, Andrew J Philpott, Glenn N Boyce, and Eugene T. Ek
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Models, Anatomic ,lcsh:Diseases of the musculoskeletal system ,Compressive Strength ,medicine.medical_treatment ,Segmental ,03 medical and health sciences ,Fracture Fixation, Internal ,0302 clinical medicine ,lcsh:Orthopedic surgery ,Fracture fixation ,Bone plate ,medicine ,Internal fixation ,Humans ,Orthopedics and Sports Medicine ,Orthogonal ,Biomechanical ,Fractures, Comminuted ,Orthodontics ,030222 orthopedics ,Comminuted ,business.industry ,Biomechanics ,Torsion (mechanics) ,Stiffness ,030208 emergency & critical care medicine ,Bending of plates ,Clavicle ,Biomechanical Phenomena ,lcsh:RD701-811 ,medicine.anatomical_structure ,Fracture ,Surgery ,lcsh:RC925-935 ,medicine.symptom ,business ,Bone Plates ,Research Article - Abstract
Background Dual orthogonal plating of clavicle fractures may provide greater stiffness and strength than unilateral plate constructs and allow the use of lower-profile plates. We aim to biomechanically compare three clavicle plating constructs in a comminuted clavicle fracture model. Method Fifteen clavicle sawbones were osteotomised, simulating a comminuted midshaft fracture and allocated to either: group 1, single superior plate (3.5 mm superior plate); group 2, combination plating (3.5 mm superior plate, 2.8 mm anterior plate) and group 3, dual mini-plates (two 2.8-mm orthogonal mini-plates). Specimens were biomechanically tested under torsion and cantilever bending. Construct stiffness (Nm/degree) and load to failure (Nm) were measured. Results Group 2 had higher torsional (0.70 vs. 0.60 Nm/deg, p = 0.017) and cantilever bending stiffness (0.61 vs. 0.51 Nm/deg, p = 0.025) than group 1. Group 3 had lower cantilever bending stiffness (0.39 vs. 0.51 Nm/deg, p p Conclusion Dual orthogonal fixation with mini-plates demonstrated lower stiffness and strength than traditional superior plating. The addition of an anterior mini-plate to a traditional superior plating improved construct stiffness and may have a role in patients seeking early return to activity. Level of evidence Basic science biomechanical study
- Published
- 2020
16. Nonspanning Total Wrist Arthrodesis with a Low-Profile Locking Plate
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Eugene T. Ek, Schneider K. Rancy, Sophia Paul, Scott W. Wolfe, and Robert N. Hotchkiss
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030222 orthopedics ,medicine.medical_specialty ,business.industry ,Inflammatory arthritis ,Arthrodesis ,medicine.medical_treatment ,030230 surgery ,Wrist ,medicine.disease ,Surgery ,Locking plate ,body regions ,03 medical and health sciences ,Grip strength ,0302 clinical medicine ,medicine.anatomical_structure ,Rheumatoid arthritis ,Carpometacarpal joint ,medicine ,Orthopedics and Sports Medicine ,Brachial Plexopathy ,business - Abstract
Purpose This study aims to compare the outcomes and complications of our technique for nonspanning total wrist arthrodesis using a locking plate with the standard carpometacarpal spanning technique. Methods A retrospective review of charts was performed to identify patients who underwent total wrist arthrodesis by the senior author (S.W.W.). We compared the outcomes of 15 cases of nonspanning wrist fusion with a 2.4/2.7 mm locking T plate to 11 cases of spanning wrist fusion with a 2.7/3.5 mm locking compression plate. Minimum follow-up was 3 months. Indications for fusion included rheumatoid arthritis, posttraumatic arthritis, Kienböck's disease, primary osteoarthritis, juvenile inflammatory arthropathy, psoriasis, brachial plexopathy, failed hemi or total wrist arthroplasty, failed four-corner fusion, and failed proximal row carpectomy. The primary outcome was fusion. Secondary outcomes included time to union, patient-rated wrist evaluation score, numerical rating scale pain score, grip strength, and complications. Results All the wrists got fused. There were no significant differences in objective and subjective outcomes between cohorts. There were three complications (27%) in the spanning group, including tendon rupture and peri-implant fracture at the third metacarpal. This was compared with three complications (20%) in the nonspanning group, consisting of hardware removal. Discussion We achieved similar fusion rates employing both spanning and nonspanning total wrist arthrodesis techniques, without necessitating carpometacarpal arthrodesis in the latter. Complications associated with our method were comparably less severe than those reported in the literature. We advocate nonspanning arthrodesis as an alternative method for total wrist fusion with a high union rate and minimal risk of complications at the carpometacarpal joint. Level of Evidence Therapeutic level IV.
- Published
- 2017
17. Isolated avascular necrosis of the olecranon
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Eugene T. Ek and Adrian K. Schneider
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030222 orthopedics ,medicine.medical_specialty ,business.industry ,Olecranon ,Avascular necrosis ,General Medicine ,medicine.disease ,Surgery ,03 medical and health sciences ,Femoral head ,0302 clinical medicine ,medicine.anatomical_structure ,Orthopedic surgery ,medicine ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,business - Published
- 2017
18. Reconstruction of the Proximal Scaphoid With a Medial Femoral Trochlea Osteochondral Graft: Minimum 2-Year Results
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Eugene T. Ek, Peter Maloney, Christopher A Powell, Stephen K.Y. Tham, Cameron Keating, and David McCombe
- Subjects
Wrist Joint ,medicine.medical_specialty ,Arthrodesis ,medicine.medical_treatment ,030230 surgery ,Wrist ,Wrist pain ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Orthopedics and Sports Medicine ,Femur ,Range of Motion, Articular ,Retrospective Studies ,Scaphoid Bone ,030222 orthopedics ,Hand Strength ,business.industry ,Surgery ,medicine.anatomical_structure ,Knee pain ,Scaphoid bone ,Fractures, Ununited ,Ulnar deviation ,medicine.symptom ,Range of motion ,business ,Oxford knee score ,Follow-Up Studies - Abstract
PURPOSE: To report the clinical and radiological outcomes after medial femoral trochlear (MFT) osteochondral graft for the salvage of proximal scaphoid fractures with a minimum 2-year follow-up. METHODS: A retrospective review was performed of patients with comminuted fractures of the proximal scaphoid treated by excision of the proximal pole and replacement with free vascularized MFT osteochondral graft. Demographic data, objective and radiographic measurements, and patient-reported outcome measures of the upper limb and knee were collected. Pain was assessed by completion of a visual analog scale (VAS). RESULTS: Between February 2014 and May 2015, 12 MFT osteochondral grafts were performed. Eight patients were available for follow-up at a mean of 34 months (range, 28-39 months). The mean range of wrist flexion was 31° (range, 15°-60°), extension was 34° (range, 5°-60°), radial deviation was 9° (range, 0°-20°), ulnar deviation was 28° (range, 10°-45°) and grip strength was 42 kg (range, 25-53 kg). The median wrist pain, as measured by VAS, was 0.7 (mean, 1.3; range, 0-6). The average follow-up scapholunate, radiolunate, and radioscaphoid angles were 58.9° (range, 44°-93°), 12.9° (range, 0°-30°), and 46.0° (range, 35°-63°), respectively. The mean Disabilities of the Arm, Shoulder, and Hand (DASH) score was 13.9 (range, 3-43) and Patient Rated Wrist Evaluation (PRWE) score was 22.4 (range, 2-68). The mean postoperative Oxford Knee Score was 42 (range, 14-48). One patient suffered notable knee pain at 37-month follow-up. One patient suffered notable pain on the radial side of the wrist and underwent scaphoid excision and 4-corner arthrodesis. CONCLUSIONS: Replacement of the fragmented proximal scaphoid by MFT graft is an alternative to other salvage options and most patients can expect pain relief and acceptable wrist motion. These results need to be balanced against the potential for donor-site morbidity. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic V.
- Published
- 2019
19. Innervation of the acromioclavicular joint by the suprascapular nerve
- Author
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Georg Feigl, Paul Borbas, Karim Eid, and Eugene T. Ek
- Subjects
musculoskeletal diseases ,030222 orthopedics ,Shoulder ,Shoulder surgery ,business.industry ,medicine.medical_treatment ,Rehabilitation ,Physical Therapy, Sports Therapy and Rehabilitation ,030229 sport sciences ,Anatomy ,Suprascapular nerve ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,medicine ,Acromioclavicular joint ,Orthopedics and Sports Medicine ,Surgery ,business - Abstract
Background The suprascapular nerve is largely responsible for the majority of the sensory innervation of the acromioclavicular joint. In this anatomical study, we describe, in detail, the anatomy of the sensory innervation of the acromioclavicular joint by the branches of the suprascapular nerve. Methods Twenty-seven shoulders from 17 cadaveric specimens were carefully dissected to identify the course of the suprascapular nerve, with the main focus being on the sensory innervation of the acromioclavicular joint. Nine specific measurements of the acromioclavicular joint sensory nerves were made of each shoulder in relation to distinct anatomical landmarks to determine the mean location and course of these nerves. Results In all 27 shoulders (100%), a sensory branch to the acromioclavicular joint with a proximal origin from the suprascapular nerve could be depicted (“first sensory branch”). The mean length of this branch was 4.3 cm (range: 3.3–5.3 cm). In 14 shoulders (52%), a further sensory branch of the suprascapular nerve innervating the posterior acromioclavicular joint capsule could be identified (“second sensory branch”). Discussion A detailed anatomical description of the sensory innervation of the acromioclavicular joint from suprascapular nerve branches was performed, which can potentially aid in the development of more focused anesthetic blockades and acromioclavicular joint denervation procedures.
- Published
- 2019
20. A cadaveric study of the three different palpation-guided techniques for glenohumeral joint injections
- Author
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Georg Feigl, Karim Eid, Matthew Ricks, Julian M Jeserschek, Paul Borbas, and Eugene T. Ek
- Subjects
030222 orthopedics ,Shoulder ,medicine.diagnostic_test ,business.industry ,Rehabilitation ,Physical Therapy, Sports Therapy and Rehabilitation ,030229 sport sciences ,Palpation ,Joint injections ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Orthopedics and Sports Medicine ,Surgery ,Nuclear medicine ,business ,Cadaveric spasm - Abstract
BackgroundIt is not known whether an anterior, posterior or superior approach using the Neviaser portal is more accurate for glenohumeral joint injections. The aim of this study was to evaluate the accuracy of the palpation-guided technique and compare the three different approaches.MethodsPalpation-guided glenohumeral joint injections were performed in 48 shoulders (24 cadavers) by two operators. Each shoulder was injected by three different approaches with a different coloured latex solution. The three approaches included the anterior, posterior and superior methods. The accuracy and location of unsuccessful injections were assessed through dissection of the shoulders.ResultsPosterior injections were the most successful with an accuracy rate of 89.6%, followed by anterior injections (75%) and superior injections (54.2%). Both posterior ( p = 0.0001) and anterior injections ( p = 0.03) were statistically significantly more accurate than superior injections. The most common failure mode was an intratendinous or intramuscular injection, which occurred most frequently with a superior approach.ConclusionsUse of a superior approach through the Neviaser portal for the palpation-guided technique for glenohumeral joint injections showed a statistically significant inferior accuracy when compared to both the posterior and anterior approaches and is therefore not recommended. Posterior approached injections were the most accurate.
- Published
- 2019
21. Surgical management of chronic high-grade acromioclavicular joint dislocations: a systematic review
- Author
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Paul Borbas, Eugene T. Ek, and James Churchill
- Subjects
Joint Instability ,medicine.medical_specialty ,medicine.medical_treatment ,Tendon Transfer ,Joint Dislocations ,Coracoid ,Arthroplasty ,03 medical and health sciences ,0302 clinical medicine ,Tendon transfer ,medicine ,Acromioclavicular joint ,Humans ,Orthopedics and Sports Medicine ,Joint dislocation ,Fixation (histology) ,030222 orthopedics ,Sutures ,business.industry ,Suture Techniques ,030229 sport sciences ,General Medicine ,Plastic Surgery Procedures ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Acromioclavicular Joint ,Clavicle ,Chronic Disease ,Ligaments, Articular ,Ligament ,business - Abstract
Background To date, no gold-standard technique exists for the treatment of chronic acromioclavicular joint (ACJ) instability. We systematically reviewed the clinical results of 3 main categories of ACJ reconstruction for high-grade chronic instability. Methods A literature search was performed according to Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The inclusion criteria were clinical studies involving patients with ACJ instability (Rockwood grades III-VI) for at least 6 weeks, managed with ACJ stabilization, with a minimum 1-year follow-up. Depending on the surgical technique, patients were divided into 1 of 3 groups: nonbiological fixation between the coracoid and clavicle, for example, suture loops and synthetic ligaments (group 1); biological reconstruction of the coracoclavicular ligaments, for example, allograft or autograft ligament reconstruction (group 2); and ligament and/or tendon transfer, for example, the Weaver-Dunn procedure (group 3). Patient demographic characteristics, functional scores, radiographic outcomes, and complications were compared. Results Two independent investigators reviewed 960 articles. A total of 27 studies met the inclusion criteria, comprising 590 patients divided into 1 of 3 groups. The complication rates were similar among the 3 groups: 15% for nonbiological fixation, 15% for biological reconstruction, and 17% for ligament and/or tendon transfer, with failure rates of 8%, 7%, and 5%, respectively. In terms of functional results, the mean Constant score was 87.2 points for nonbiological fixation (n = 89), 92.4 points for biological reconstruction (n = 86), and 87.4 points for ligament and/or tendon transfer (n = 49). Conclusion On comparison of the results of 3 different ACJ reconstruction methods, all techniques showed similar complication rates. Among the level II studies, ACJ reconstruction with a tendon graft showed superior results.
- Published
- 2018
22. Measurement of Scaphoid Bone Microarchitecture: A Computed Tomography Imaging Study and Implications for Screw Placement
- Author
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Stephen K.Y. Tham, Avanthi Mandaleson, Freya Hik, Eugene T. Ek, David C. Ackland, and Lachlan S Huntington
- Subjects
medicine.medical_specialty ,X-ray microtomography ,genetic structures ,Bone density ,Bone Screws ,Scaphoid fracture ,030230 surgery ,Fracture Fixation, Internal ,Fractures, Bone ,03 medical and health sciences ,0302 clinical medicine ,Fracture fixation ,Humans ,Medicine ,Orthopedics and Sports Medicine ,Fixation (histology) ,Scaphoid Bone ,030222 orthopedics ,business.industry ,X-Ray Microtomography ,Anatomy ,medicine.disease ,Scaphoid bone ,Orthopedic surgery ,Surgery ,sense organs ,business ,Cadaveric spasm - Abstract
Purpose High bone density and quality is associated with improved screw fixation in fracture fixation. The objective of this study was to assess bone density and quality in the proximal and distal scaphoid to determine optimum sites for placement of 2 screws in scaphoid fracture fixation. Methods Twenty-nine cadaveric human scaphoid specimens were harvested and scanned using micro–computed tomography. Bone density (bone volume fraction) and bone quality (relative bone surface area, trabecular number, and trabecular thickness) were evaluated in 4 quadrants within each of the proximal and distal scaphoid. Results The proximal radial quadrant of the scaphoid had significantly greater bone volume than the distal ulnar (mean difference, 33.2%) and distal volar quadrants (mean difference, 32.3%). There was a significantly greater trabecular number in the proximal radial quadrant than in the distal ulnar (mean difference, 16.7%) and in the distal volar quadrants (mean difference, 15.9%) and between the proximal ulnar and the distal ulnar quadrants (mean difference, 12%). There was a significantly greater bone surface area in the proximal radial and distal radial quadrants than in the distal ulnar and distal volar quadrants. There were no significant differences in trabecular thickness between the 8 analyzed quadrants Conclusions Although there are differences in bone volume, trabecular number, and bone surface area between the proximal pole of the scaphoid and that of the distal pole, there were no significant differences in the bone quality (trabecular thickness, trabecular number, and relative bone surface area) and density (bone volume fraction) between the 4 quadrants of the proximal or distal pole of the cadaveric scaphoids studied. Clinical relevance Insertion of 2 headless compression screws can be determined by ease of surgical access and ease of screw positioning and not by differences in bone quality or density of the proximal or distal scaphoid.
- Published
- 2020
23. Isolated Proximal Radioulnar Joint Instability
- Author
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Eugene T. Ek and Richard P Jamieson
- Subjects
Joint Instability ,business.industry ,Interosseous membrane ,Biomechanics ,Treatment options ,Anatomy ,Instability ,medicine.anatomical_structure ,Forearm ,Elbow Joint ,medicine ,Ligament ,Humans ,Orthopedic Procedures ,Orthopedics and Sports Medicine ,Surgery ,Presentation (obstetrics) ,business ,Proximal radioulnar joint - Abstract
Isolated proximal radioulnar joint instability is an uncommon and often challenging problem that may manifest as recurrent instability of the proximal aspect of the radius, usually during forearm pronation and supination. Instability is due to deficiency of the stabilizing structures around the proximal aspect of the radius, and biomechanical studies have highlighted the importance of the annular ligament and the interosseous membrane in both transverse and longitudinal plane stability. Reconstruction of the stabilizing structures around the radial head often is indicated in cases of recurrent instability and includes joint-preserving procedures such as annular ligament reconstruction, proximal ulnar osteotomy, and interosseous membrane reconstruction. Rarely, salvage procedures such as interpositional arthroplasty or 1-bone forearm reconstruction are necessary. A thorough understanding of the anatomic structures that stabilize the proximal aspect of the radius and the complexities of forearm biomechanics is required in order to successfully diagnose and manage this condition.
- Published
- 2020
24. The Twist X-Ray: A Novel Test for Dynamic Scapholunate Instability
- Author
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Tony Goldring, Andrew H. Rotstein, Jason N. Harvey, Marc Garcia-Elias, Sheena K. Sikora, Eugene T. Ek, and Stephen K.Y. Tham
- Subjects
Orthodontics ,030222 orthopedics ,medicine.diagnostic_test ,business.industry ,Ulna ,Clenched fist ,Magnetic resonance imaging ,030230 surgery ,Scapholunate ligament ,Wrist ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,medicine ,Ligament ,Wrist arthroscopy ,Orthopedics and Sports Medicine ,Surgery ,Ulnar deviation ,business - Abstract
Background Scapholunate instability (SLI) is the most common form of carpal instability. Early detection of SLI is imperative as early reconstructive procedures can potentially prevent the natural history of progressive degenerative arthritis. After wrist arthroscopy, magnetic resonance imaging (MRI) remains the next best noninvasive diagnostic option; however, access still remains costly and is often limited in many health care systems worldwide. In this article, we describe a novel device that allows for dynamic X-rays to be taken, accentuating the scapholunate (SL) widening. Description of Technique Twist X-ray views are generated by the patient clenching a device that combines the standard clenched fist views with ulnar deviation and supination. The test is easy to perform and functions by combining a higher grip force with the ulnar deviation and pronation effects of the extensor carpi ulnaris tendon, thus accentuating the SL gap in dynamic instability. Patients and Methods We present a series of four patients with dynamic SLI and compare the findings of the Twist X-rays with conventional wrist X-rays series, including standard anteroposterior, lateral, radial, and ulna deviation, clenched fist, and pencil grip views. Results In all the four patients, there was substantial dynamic SL widening. The SL interval increased from a mean of 1.8 mm (range: 1.5–2.8) on posteroanterior X-rays to 6.3 mm (range: 4.6–8.2) with the Twist views. Interestingly, on the pencil grip view, the mean widening was only 1.5 mm (range: 1–2.8 mm). Conclusion The authors describe a novel device that allows for improved detection of dynamic SL ligament instability when performing stress X-ray views of the wrist. Level of Evidence This is a Level IV study.
- Published
- 2018
25. Arthroscopic Repair of the Lateral Ulnar Collateral Ligament of the Elbow Using a Knotless Suture Anchor
- Author
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Kemble K. Wang and Eugene T. Ek
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,Elbow ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,hemic and lymphatic diseases ,medicine ,Technical Note ,otorhinolaryngologic diseases ,Orthopedics and Sports Medicine ,Lateral epicondyle ,Humerus ,Suture anchors ,Orthopedic surgery ,030222 orthopedics ,business.industry ,030229 sport sciences ,Insertion point ,musculoskeletal system ,Surgery ,stomatognathic diseases ,medicine.anatomical_structure ,Rotatory instability ,Ligament ,business ,RD701-811 - Abstract
The lateral collateral ligament (LCL) complex of the elbow plays a crucial role in the stability of the elbow joint, especially to varus loads. Deficiency of particularly the lateral ulnar collateral component of the LCL can lead to chronic posterolateral rotatory instability, which can be functionally debilitating and can lead to a rapid onset of early degenerative arthritis. Commonly, in the setting of acute rupture of the LCL, the ligament is repaired using an open technique with suture anchor fixation to the lateral epicondyle insertion point. However, with advancing arthroscopic techniques, it has become possible to repair the LCL arthroscopically. We present a relatively simple method for an all-arthroscopic repair of the LCL to the humerus using a knotless suture anchor technique.
- Published
- 2018
26. Biomechanical Analysis of Scapholunate Ligament Repair Techniques
- Author
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Michelle G. Carlson, Eugene T. Ek, Kathleen N. Meyers, Krystle A. Hearns, Lana Kang, and Mike T. Wei
- Subjects
Scaphoid Bone ,Fibrous joint ,medicine.medical_specialty ,Carpal Joints ,business.industry ,Suture Techniques ,Scapholunate joint ,Wrist ,Scapholunate ligament ,Surgery ,medicine.anatomical_structure ,Cadaver ,Suture Anchors ,Tensile Strength ,Ligaments, Articular ,Load to failure ,Ligament ,medicine ,Humans ,Orthopedics and Sports Medicine ,Lunate Bone ,business ,Cadaveric spasm - Abstract
Purpose To evaluate the biomechanical properties of 3 scapholunate repair techniques. Methods In 51 cadavers, the scapholunate ligament was exposed through a dorsal approach, incised at its scaphoid insertion, and repaired using 1 of 3 techniques: 2 single-loaded suture anchors, 2 double-loaded suture anchors, or 2 transosseous sutures. Twenty-four repaired specimens underwent load to failure (LTF) testing using tensile distraction on a servo-hydraulic machine. Twenty-seven specimens underwent cyclical testing to measure gap formation at the scapholunate joint. Results The mode of failure was suture pullout through the substance of the ligament in 22 specimens, failure at the bone suture interface in 1, and anchor pullout in 1. Double-loaded anchor repairs demonstrated a significantly higher mean ultimate LTF compared with single-loaded anchor (91 N vs 35 N) and transosseous (91 N vs 60 N) repairs. Transosseous repairs demonstrated a higher mean ultimate LTF compared with single-loaded suture repairs (60 N vs 35 N). After 300 cycles, the average gap for the transosseous repair group was double that for the single- and double-loaded repairs, although not statistically significant. Conclusions Primary scapholunate ligament repairs using double-loaded suture anchors demonstrated significantly higher strength compared with single-loaded anchors and transosseous repairs. On cyclic loading, transosseous repairs demonstrated the greatest gap formation with no measurable difference between single- and double-loaded repairs. Clinical relevance In a cadaveric model for primary repairs, double-loaded suture anchors demonstrated the highest LTF and offer a similar but unproven performance in vivo .
- Published
- 2015
27. Open Rotator Cuff Repair
- Author
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Jennifer Flynn, Malin Wijeratna, Gregory A. Hoy, and Eugene T. Ek
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Gold standard ,Physical examination ,musculoskeletal system ,Surgery ,medicine.anatomical_structure ,Cuff ,Orthopedic surgery ,medicine ,Tears ,Orthopedics and Sports Medicine ,Rotator cuff ,business - Abstract
Open rotator cuff repair remains the gold standard for addressing large, retracted rotator cuff tears. Despite advances in arthroscopic techniques, to date, there is a lack of consistent evidence that one technique is superior. We review anatomical considerations in rotator cuff tear development as well as clinical examination and useful investigations. Open approach to rotator cuff repair is used in combination with arthroscopic assessment and preparation. Indications for an open approach relate to size, mobility, and configuration of the tear. The open approach to cuff repair cannot compensate for irreparable, chronic, immobile tears. In this article, we review the technical considerations of open rotator cuff repair.
- Published
- 2015
28. Surgical treatment of isolated type II superior labrum anterior-posterior (SLAP) lesions: repair versus biceps tenodesis
- Author
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Eugene T. Ek, Jeffrey D. Tompson, Michael T. Freehill, Jon J.P. Warner, and Lewis L. Shi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Soft Tissue Injuries ,Glenoid labrum ,Elbow ,Tenodesis ,Biceps ,Cohort Studies ,Arthroscopy ,Scapula ,Tendon Injuries ,medicine ,Humans ,Orthopedics and Sports Medicine ,Retrospective Studies ,Labrum ,medicine.diagnostic_test ,Shoulder Joint ,business.industry ,Fibrocartilage ,General Medicine ,Middle Aged ,Surgery ,medicine.anatomical_structure ,Orthopedic surgery ,Female ,Shoulder joint ,Shoulder Injuries ,business - Abstract
Background It is still unclear which patients with isolated type II superior labrum anterior-posterior (SLAP) lesions benefit from either superior labral repair or biceps tenodesis. This study evaluates the indications and outcomes of patients with isolated type II SLAP lesions who have undergone either procedure. Methods A retrospective analysis was performed of patients who had surgery for an isolated type II SLAP lesion between 2008 and 2011. There were 25 patients: 15 underwent biceps tenodesis, with a mean follow-up of 31 months (range, 26-43 months), and 10 underwent SLAP repair, with a mean follow-up of 35 months (range, 25-52 months). The mean age was 47 years (range, 30-59 years) in the tenodesis group and 31 years (range, 21-43 years) in the repair group. Results At latest follow-up, both groups showed significant improvements in subjective shoulder value and pain score. No difference was observed in American Shoulder and Elbow Surgeons score (93.0 vs 93.5, P = .45), patient satisfaction (93% vs 90%, P = .45), or return to preinjury sporting level (73% vs 60%, P = .66). Analysis of the indications for treatment showed that in the large majority, tenodesis was performed in older patients (>35 years) and patients who showed degenerative or frayed labrums whereas SLAP repairs were performed in younger and more active patients with healthy-appearing labral tissue. There was only 1 failure in the tenodesis group, and in the SLAP repair group, there were 2 cases of postoperative stiffness; all were treated nonoperatively. Conclusion In this study, we show that both biceps tenodesis and SLAP repair can provide good to excellent results if performed in appropriately selected patients with isolated type II SLAP lesions.
- Published
- 2014
29. Carpal Fractures
- Author
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Nina, Suh, Eugene T, Ek, and Scott W, Wolfe
- Subjects
Fractures, Bone ,Pisiform Bone ,Triquetrum Bone ,Trapezium Bone ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Tomography, X-Ray Computed ,Wrist Injuries ,Hamate Bone ,Carpal Bones ,Capitate Bone - Abstract
Carpal fractures are exceedingly rare clinical entities and are often associated with concomitant injuries. In this review, we focus on fractures of the carpus, excluding the scaphoid, and provide an update on the current consensus as to mechanism, diagnosis, management, outcomes, and complications after such injuries.
- Published
- 2014
30. Scaphoid Fracture Fixation in a Nonunion Model: A Biomechanical Study Comparing 3 Types of Fixation
- Author
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Craig Lewis, David C. Ackland, Stephen K.Y. Tham, Avanthi Mandaleson, and Eugene T. Ek
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,medicine.medical_treatment ,Nonunion ,Bone Screws ,Scaphoid fracture ,030230 surgery ,03 medical and health sciences ,Fixation (surgical) ,Fracture Fixation, Internal ,0302 clinical medicine ,Fracture fixation ,Bone plate ,Materials Testing ,medicine ,Cadaver ,Internal fixation ,Humans ,Orthopedics and Sports Medicine ,Orthodontics ,Scaphoid Bone ,030222 orthopedics ,business.industry ,musculoskeletal system ,equipment and supplies ,medicine.disease ,Surgery ,surgical procedures, operative ,Scaphoid bone ,Fractures, Ununited ,Stress, Mechanical ,Cadaveric spasm ,business ,Bone Plates - Abstract
Purpose Union of a scaphoid fracture after fixation is influenced by various factors, one of which is fracture stability. This study aims to compare the biomechanical stability of 3 different types of scaphoid fracture fixation in a scaphoid nonunion model. Methods Thirty cadaveric scaphoid specimens were assigned to one of 3 different fixation groups: (1) single 3.0-mm compression screw, (2) two 2.2-mm screws, and (3) scaphoid plate. A 3-mm volar wedge osteotomy was created at the scaphoid waist to simulate a nonunion model. The primary outcome measure was load to failure, whereas secondary outcome measures were load to 2-mm displacement, energy absorbed, stiffness, and mode of failure, recorded by video and retrieval analysis. Results There was a significantly lower load to failure in the single screw construct compared with that in the double screw (mean difference 187.2 N) and plate fixation constructs (mean difference 150.7 N). The mean load to 2-mm displacement in the single screw construct (91.5 N) was also significantly lower than that in the double screw (181.8 N) and plate fixation constructs (197.2 N). There was a significantly lower stiffness with the single screw fixation compared with that of the double screws (mean difference 85.4 N/mm), and lower energy absorbed with single screws when compared with that of double screws (mean difference 386.5 mJ) and when compared with plate fixation (mean difference 270.8 mJ). Conclusions In this biomechanical study comparing fixation methods using a model of scaphoid nonunion with bone loss, we found that double screws or plate fixation demonstrated significantly greater stability, stiffness, and energy absorption when compared with a single compression screw. We found no discernible differences between double screw fixation and the plate groups. Clinical relevance The use of double screws or plate fixation in a nonunion setting may allow accelerated rehabilitation without compromise to fracture stability.
- Published
- 2016
31. Propionibacterium Acnes Infection of a Metacarpophalangeal Joint Arthroplasty
- Author
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Sheena K. Sikora, Guillaume Bacle, and Eugene T. Ek
- Subjects
Male ,Reoperation ,medicine.medical_specialty ,Prosthesis-Related Infections ,medicine.drug_class ,medicine.medical_treatment ,Joint Prosthesis ,Antibiotics ,Prosthesis ,Late presentation ,Metacarpophalangeal Joint ,03 medical and health sciences ,Propionibacterium acnes ,0302 clinical medicine ,medicine ,Humans ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,Arthroplasty, Replacement ,Silastic implant ,Gram-Positive Bacterial Infections ,Aged ,030222 orthopedics ,biology ,business.industry ,Metacarpophalangeal joint ,biology.organism_classification ,Arthroplasty ,Surgery ,Anti-Bacterial Agents ,medicine.anatomical_structure ,business - Abstract
Neglected and underestimated in the past, Propionibacterium acnes is currently the most prevalent organism associated with deep prosthetic infections around the shoulder. Surprisingly, it has never been reported as a cause of infection in the hand. Here we report a case of a late presentation of a P. acnes infection in a metacarpophalangeal joint replacement, resulting in chronic low-grade pain with movement. The patient underwent a 2-stage revision, with initial removal of the prosthesis. Positive cultures for P. acnes required 15 days of extended incubation. The patient subsequently had 6 weeks of oral antibiotics followed by a second-stage revision with a Silastic implant.
- Published
- 2016
32. Fixation of the Fractured Lunate in Kienböck Disease
- Author
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Guillaume Bacle, Justin Chou, Eugene T. Ek, and Stephen K.Y. Tham
- Subjects
Adult ,Male ,Adolescent ,Visual Analog Scale ,Visual analogue scale ,medicine.medical_treatment ,Radiography ,Bone Screws ,030230 surgery ,Wrist pain ,Wrist ,Disability Evaluation ,Fracture Fixation, Internal ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,medicine ,Humans ,Internal fixation ,Orthopedics and Sports Medicine ,Lunate Bone ,Retrospective Studies ,Fracture Healing ,Orthodontics ,030222 orthopedics ,business.industry ,Osteonecrosis ,Lunate ,Radius ,Fractures, Spontaneous ,medicine.anatomical_structure ,Coronal plane ,Cancellous Bone ,Female ,Surgery ,medicine.symptom ,Tomography, X-Ray Computed ,business ,Follow-Up Studies - Abstract
Purpose To describe an uncommon subset of fractured lunates in Kienbock disease that is salvageable by internal fixation. Methods We performed a retrospective review for patients with Kienbock disease treated by internal fixation. Demographic data, objective and radiographic measurements, patient-reported outcome measures (Disabilities of the Arm, Shoulder, and Hand and Patient-Rated Wrist Evaluation) and pain (visual analog scale) scores were collected. Results Of the 7 patients treated, 5 were available for review. At an average follow-up of 7.1 years (range, 1.5–15 years), all patients had activity-related wrist pain but were pain-free at rest. Radiographic assessment showed union in all lunates and a normal radioscaphoid angle and Stahl index. The modified carpal height ratio was reduced in 4 patients and normal in one. There was no observed narrowing or irregularity of the radiocarpal or midcarpal joints. Patient-reported outcome measures in 2 patients were unsatisfactory. Conclusions Computed tomography of the lunate in Kienbock disease is an important investigative tool. A coronal split fracture of these lunates can be salvageable by internal fixation. Revascularization of the lunate can be performed when the fragment is of sufficient size. Type of study/level of evidence Therapeutic V.
- Published
- 2019
33. A comparative analysis of fatty infiltration and muscle atrophy in patients with chronic rotator cuff tears and suprascapular neuropathy
- Author
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Christian Gerber, Silvan Beeler, and Eugene T. Ek
- Subjects
Adult ,Male ,Shoulder ,medicine.medical_specialty ,Shoulders ,Rotator Cuff Injuries ,Rotator Cuff ,Tendon Injuries ,medicine ,Humans ,Orthopedics and Sports Medicine ,Rotator cuff ,Arthrography ,Muscle, Skeletal ,Aged ,Retrospective Studies ,Aged, 80 and over ,Denervation ,medicine.diagnostic_test ,business.industry ,Peripheral Nervous System Diseases ,Magnetic resonance imaging ,General Medicine ,Middle Aged ,Suprascapular nerve ,musculoskeletal system ,Magnetic Resonance Imaging ,Muscle atrophy ,Surgery ,Muscular Atrophy ,medicine.anatomical_structure ,Adipose Tissue ,Chronic Disease ,Cuff ,Tears ,Female ,medicine.symptom ,business - Abstract
Background Little is known of the mechanisms that lead to the muscle changes associated with rotator cuff disorders. We have observed that the magnetic resonance imaging (MRI) appearance of fatty infiltration (FI) and muscle atrophy (MA) differ between chronic cuff tears and suprascapular neuropathy, suggesting different pathophysiology. This study compares the different MRI changes that occur in chronic cuff tears and suprascapular neuropathy. Methods Two groups were retrospectively identified: (1) RCT group (20 shoulders): patients with chronic tears of the supraspinatus and/or infraspinatus without electromyographic (EMG) evidence of suprascapular neuropathy; (2) neuro group (17 shoulders): patients with EMG documented suprascapular nerve dysfunction and absence of a rotator cuff tear. Magnetic resonance arthrograms were analyzed for the degree of FI and MA, and the morphology of the muscle was assessed, in particular the muscle border, pattern of FI, and extent of involvement. Results The muscle changes that occur following chronic cuff tears differ from that following denervation secondary to suprascapular neuropathy, especially with respect to the muscle border, degree of perineural fat, and overall distribution of FI. Highly specific and characteristic morphological patterns of FI exist for both chronic cuff tears and suprascapular neuropathy. Conclusion Chronic rotator cuff tendon tears and suprascapular neuropathy are both associated with FI and MA of the rotator cuff muscles. The pattern of FI is markedly different in the 2 situations. These findings have diagnostic potential and may serve as a basis for further research concerning type, severity, and evolution of FI under different conditions and after treatment.
- Published
- 2013
34. The long leg radiograph is a reliable method of assessing alignment when compared to computer-assisted navigation and computer tomography
- Author
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Sina Babazadeh, Michelle M. Dowsey, Roger Bingham, Peter F. M. Choong, Eugene T. Ek, and James D. Stoney
- Subjects
Male ,medicine.medical_specialty ,Knee Joint ,medicine.medical_treatment ,Radiography ,Knee replacement ,Prosthesis Fitting ,medicine ,Medical imaging ,Humans ,Orthopedics and Sports Medicine ,Prospective Studies ,Arthroplasty, Replacement, Knee ,Aged ,Aged, 80 and over ,Observer Variation ,Computer-assisted surgery ,Reproducibility ,Modality (human–computer interaction) ,business.industry ,Reproducibility of Results ,Repeatability ,Middle Aged ,Surgery ,Surgery, Computer-Assisted ,Female ,Hip Joint ,Tomography ,Knee Prosthesis ,Tomography, X-Ray Computed ,business ,Nuclear medicine ,Ankle Joint - Abstract
article i nfo Background: The mechanical alignment of the knee is an important factor in planning for, and subsequently assessing the success of a knee replacement. It is most commonly measured using a long-leg anteroposterior radiograph (LLR) encompassing the hip, knee and ankle. Other modalities of measuring alignment include computer tomography (CT) and intra-operative computer navigation (Cas). Recent studies comparing LLRs to Cas in measuring alignment have shown significant differences between the two and have hypothesized that Cas is a more accurate modality. This study aims to investigate the accuracy of the above mentioned mo- dalities. Methodology: A prospective study was undertaken comparing alignment as measured by long-leg radio- graphs and computer tomography to intra-operative navigation measurements in 40 patients undergoing a primary total knee replacement to test this hypothesis. Alignment was measured three times by three ob- servers. Intra- and inter-observer correlation was sought between modalities. Results: Intra-observer correlation was excellent in all cases (>0.98) with a coefficient of repeatability b1.1°. Inter-observer correlation was also excellent measuring >0.960 using LLRs and >0.970 using CT with coef- ficient of repeatability b2.8°. Inter-modality correlation proved to be higher when comparing LLRs and CT (>0.893), than when comparing either of these modalities with Cas (>0.643 and >0.671 respectively). Pre-operative values had the greatest variability. Conclusion: Given its availability and reduced radiation dose when compared to CT, LLRs should remain the mainstay of measuring the mechanical alignment of the lower limb, especially post-operatively. Level of evidence: II
- Published
- 2013
35. Early unprotected return to contact sport after metacarpal fixation in professional athletes
- Author
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G. Couzens, Eugene T. Ek, Hamish Anderson, Matthew A. Yalizis, and Gregory A. Hoy
- Subjects
Adult ,Male ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Bone Screws ,Screw fixation ,Return to sport ,03 medical and health sciences ,Fixation (surgical) ,Fracture Fixation, Internal ,Fractures, Bone ,Young Adult ,0302 clinical medicine ,Metacarpal fracture ,medicine ,Internal fixation ,Humans ,Orthopedics and Sports Medicine ,Retrospective Studies ,030222 orthopedics ,Football players ,business.industry ,Mean age ,030229 sport sciences ,Recovery of Function ,Metacarpal Bones ,Contact sport ,Athletes ,Physical therapy ,Surgery ,Female ,business ,Bone Plates ,Follow-Up Studies - Abstract
Aims To determine whether an early return to sport in professional Australian Rules Football players after fixation of a non-thumb metacarpal fracture was safe and effective. Patients and Methods A total of 16 patients with a mean age of 25 years (19 to 30) identified as having a non-thumb metacarpal fracture underwent open reduction and internal plate and screw fixation. We compared the players’ professional performance statistics before and after the injury to determine whether there was any deterioration in their post-operative performance. Results Of the 16, 12 sustained their fracture during the season: their mean time to return to unrestricted professional play was two weeks (1 to 5). All except two of the 48 player performance variables showed no reduction in performance post-operatively. Conclusion Our data suggest that professional athletes who sustained a non-thumb metacarpal fracture can safely return to professional play without restriction two weeks after internal fixation. Cite this article: Bone Joint J 2017;99-B:1343–7.
- Published
- 2016
36. Interobserver and intraobserver variability of glenoid track measurements
- Author
-
Matthew C Evans, Adrian K. Schneider, Gregory A. Hoy, Andrew H. Rotstein, Julie Tate, Eugene T. Ek, and David Taylor
- Subjects
Adult ,Joint Instability ,Male ,medicine.medical_specialty ,Glenoid Cavity ,Coefficient of variation ,Glenoid cavity ,03 medical and health sciences ,0302 clinical medicine ,Hill–Sachs lesion ,Imaging, Three-Dimensional ,medicine ,Humans ,Orthopedics and Sports Medicine ,Reliability (statistics) ,Observer Variation ,030222 orthopedics ,Reproducibility ,business.industry ,Shoulder Joint ,Reproducibility of Results ,030229 sport sciences ,General Medicine ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Orthopedic surgery ,Humeral Head ,Shoulder joint ,Female ,Tomography ,Nuclear medicine ,business ,Tomography, X-Ray Computed - Abstract
Background A method of assessing combined glenoid and humeral bone loss in traumatic shoulder instability with an associated treatment protocol was recently published. The aim of this study was to investigate its reliability and reproducibility. Methods Seventy-one patients with unilateral anteroinferior shoulder instability underwent computed tomography scans, from which 3-dimensional images were derived. En face views of both glenoid fossae and with 3 views of the humeral head were provided to 4 assessors to determine interobserver reliability. From these measurements, the shoulder was assigned a treatment classification. Two observers repeated their assessments 1 month later to determine intraobserver reliability. For each measurement, the mean coefficient of variability was calculated. Results Assessment of glenoid bone loss showed good interobserver (4 observers agreeing in 90.1% of cases) and also good intraobserver agreement (94% and 96%). There was a poor level of interobserver reliability regarding the on-track or off-track classification (72%). Intraobserver reliability for this measurement was less variable (90% and 80%). There was a poor level of agreement between observers (65%) regarding treatment classification. The coefficient of variability for the Hill-Sachs lesion measured 19.2%, indicating a high level of variability for this measurement compared with Conclusion Linear bone loss on the glenoid can be measured reliably and reproducibly; however, evaluation of Hill-Sachs lesions demonstrates a high level of variability, and poor interobserver reliability.
- Published
- 2016
37. Outcomes after operative treatment of elbow contractures in the pediatric and adolescent population
- Author
-
Robert N. Hotchkiss, Sophia Paul, and Eugene T. Ek
- Subjects
Male ,medicine.medical_specialty ,Contracture ,Adolescent ,Rotation ,OSTEOCHONDRITIS DESSICANS ,Elbow ,03 medical and health sciences ,0302 clinical medicine ,Hematoma ,Elbow Joint ,medicine ,Humans ,Orthopedics and Sports Medicine ,Range of Motion, Articular ,Child ,Retrospective Studies ,Postoperative Care ,030222 orthopedics ,business.industry ,Motion Therapy, Continuous Passive ,030229 sport sciences ,General Medicine ,medicine.disease ,Surgery ,Adolescent population ,Elbow contractures ,medicine.anatomical_structure ,Anesthesia ,Child, Preschool ,Female ,medicine.symptom ,Range of motion ,business ,Manipulation under anesthesia - Abstract
Background The role of elbow contracture release in the very young is unclear, with existing studies reporting conflicting results. This study evaluated the long-term results after open elbow contracture release in patients aged younger than 18 years. Methods Between 1994 and 2012, 32 patients underwent open elbow contracture release at a mean age of 13.8 years (range, 5-18 years), and their outcomes were reviewed. The primary cause was traumatic in 30 patients (4 radial head/neck fractures, 5 intra-articular distal humeral fractures, 11 extra-articular distal humeral fractures, 10 complex fracture-dislocations), and the mean time from the index injury to contracture release was 16.3 months (range, 3-82 months). The cause in 2 patients was nontraumatic (1 osteochondritis dessicans, 1 congenital). The mean follow-up period was 66 months (range, 7-202 months). Results At the latest follow-up, total arc of motion improved from 69° to 123° ( P .0001), with a mean increase of 54° ( P .0001). The function arc was >100° in 28 patients (88%), and 29 patients (91%) achieved >20° of improvement in their arc. Twelve patients (38%) underwent a gentle manipulation under anesthesia at a mean of 2.7 weeks (range, 1-5 weeks) for early recurrence of stiffness. There were 3 complications (1 deep infection, 1 hematoma, 1 humeral fracture through the external fixator pin site). No patients lost motion after surgery. Conclusion Elbow contracture release in the pediatric and adolescent population can provide significant improvements in range of motion similar to that achieved in adults. The improvements in motion are durable.
- Published
- 2016
38. Controlled Laboratory Testing of Arthroscopic Shaver Systems: Do Blades, Contact Pressure, and Speed Influence Their Performance?
- Author
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Dominik C. Meyer, Christian Gerber, Karl Wieser, Matthias Erschbamer, Stefan Neuhofer, Eugene T. Ek, University of Zurich, and Wieser, Karl
- Subjects
medicine.medical_specialty ,Achilles tendon surgery ,610 Medicine & health ,Materials testing ,Achilles Tendon ,Menisci, Tibial ,Models, Biological ,Laboratory testing ,Resection ,Arthroscopy ,2732 Orthopedics and Sports Medicine ,Materials Testing ,Animals ,Medicine ,Orthopedics and Sports Medicine ,Orthodontics ,business.industry ,Rotational speed ,Equipment Design ,Patella ,Surgery ,Models, Animal ,Cattle ,10046 Balgrist University Hospital, Swiss Spinal Cord Injury Center ,business ,Contact pressure - Abstract
The purposes of this study were (1) to establish a reproducible, standardized testing protocol to evaluate the performance of different shaver systems and blades in a controlled, laboratory setting, and (2) to determine the optimal use of different blades with respect to the influence of contact pressure and speed of blade rotation.A holding device was developed for reproducible testing of soft-tissue (tendon and meniscal) resection performance in a submerged environment, after loading of the shaver with interchangeable weights. The Karl Storz Powershaver S2 (Karl Storz, Tuttlingen, Germany), the Stryker Power Shaver System (Stryker, Kalamazoo, MI), and the Dyonics Power Shaver System (SmithNephew, Andover, MA) were tested, with different 5.5-mm shaver blades and varied contact pressure and rotation speed. For quality testing, serrated shaver blades were evaluated at 40× image magnification. Overall, more than 150 test cycles were performed.No significant differences could be detected between comparable blade types from different manufacturers. Shavers with a serrated inner blade and smooth outer blade performed significantly better than the standard smooth resectors (P.001). Teeth on the outer layer of the blade did not lead to any further improvement of resection (P = .482). Optimal contact pressure ranged between 6 and 8 N, and optimal speed was found to be 2,000 to 2,500 rpm. Minimal blunting of the shaver blades occurred after soft-tissue resection; however, with bone resection, progressive blunting of the shaver blades was observed.Arthroscopic shavers can be tested in a controlled setting. The performance of the tested shaver types appears to be fairly independent of the manufacturer. For tendon resection, a smooth outer blade and serrated inner blade were optimal.This is one of the first established independent and quantitative assessments of arthroscopic shaver systems and blades. We believe that this study will assist the surgeon in choosing the optimal tool for the desired effect.
- Published
- 2012
39. Stitch positioning influences the suture hold in supraspinatus tendon repair
- Author
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Dominik C. Meyer, Stefan Rahm, Karl Wieser, Eugene T. Ek, Mazda Farshad, Christian Gerber, University of Zurich, and Wieser, Karl
- Subjects
medicine.medical_specialty ,Sutures ,business.industry ,610 Medicine & health ,Anatomy ,musculoskeletal system ,142-005 142-005 ,Supraspinatus tendon ,2746 Surgery ,Tendon ,Tendons ,Rotator Cuff ,2732 Orthopedics and Sports Medicine ,medicine.anatomical_structure ,Suture (anatomy) ,Tensile Strength ,Orthopedic surgery ,Cadaver ,Humans ,Medicine ,Orthopedic Procedures ,Orthopedics and Sports Medicine ,Surgery ,Stress, Mechanical ,business - Abstract
Purpose: This study was designed to compare the pull-out strength of simple suture stitches in human supraspinatus tendons with respect to the position of the rotator cable. Methods: Fifty-four tests were performed on 6 intact, human supraspinatus tendons, to assess the cutout strength of a simple suture configuration in different positions; medial to, lateral to, or within the rotator cable. Tendon thickness was measured and correlated for each positioned suture. Results: Suture positioning lateral to or in the rotator cable showed significantly lower suture retention properties compared with positioning the suture medial to the cable (p=0.002). In all tested specimens, the central stitch in the row medial to the rotator cable provided the optimum retention properties (mean: 191N; SD:±44; p
- Published
- 2012
40. PEDF-derived synthetic peptides exhibit antitumor activity in an orthotopic model of human osteosarcoma
- Author
-
Karla G. Contreras, Eugene T. Ek, Peter F. M. Choong, and Crispin R. Dass
- Subjects
Vascular Endothelial Growth Factor A ,Lung Neoplasms ,Angiogenesis ,Mice, Nude ,Antineoplastic Agents ,Bone Neoplasms ,Biology ,Neovascularization ,Epitopes ,Mice ,PEDF ,Osteogenesis ,Cell Line, Tumor ,medicine ,Animals ,Humans ,Orthopedics and Sports Medicine ,Nerve Growth Factors ,Neoplasm Metastasis ,Eye Proteins ,Cell adhesion ,Serpins ,Cell Proliferation ,Tube formation ,Mice, Inbred BALB C ,Osteosarcoma ,Neovascularization, Pathologic ,Cell growth ,medicine.disease ,Gene Expression Regulation, Neoplastic ,Vascular endothelial growth factor A ,Immunology ,Cancer research ,medicine.symptom ,Peptides - Abstract
Pigment epithelium-derived factor (PEDF) is one of the most potent inhibitors of angiogenesis, and has recently been demonstrated to have an important multifunctional role in tumor growth, invasion, and metastasis. However, relatively little is known of mechanisms through which PEDF exerts its antitumor activity. Therefore, with the aim of identifying potential functional epitopes specifically against osteosarcoma, we evaluated the bioactivity of four 25-mer synthetic PEDF-derived peptides (termed StVOrth-1, -2 -3, and -4) against a human osteosarcoma cell line, SaOS-2. We found that StVOrth-2 (residues 78-102) predominantly inhibited tumor cell proliferation, while StVOrth-3 (residues 90-114) markedly increased cellular adhesion to collagen type-1, with StVOrth-4 (residues 387-411) demonstrating most significant inhibition of Matrigel invasion. Furthermore, we show that StVOrth-1 (residues 40-64), -2 and -3 induce osteoblastic differentiation, evidenced by increased mineralized nodule formation. Interestingly, although no peptide inhibited angiogenesis in the tube formation assay, StVOrth-3 and -4 markedly suppressed VEGF expression. We further tested the activity of StVOrth-2 and StVOrth-3 in vivo, in an orthotopic model of osteosarcoma and found that both peptides significantly inhibited primary tumor growth and the development of pulmonary metastases. Together these results provide greater insight into the potential mechanisms through which PEDF exerts its antitumor function. Furthermore, this raises the possibility of developing short PEDF fragments as lead compounds for the treatment of osteosarcoma.
- Published
- 2007
41. Use of a Bone Graft Drill Harvester to Create the Fenestration During Arthroscopic Ulnohumeral Arthroplasty
- Author
-
Malin Wijeratna, Gregory A. Hoy, Ash Chehata, and Eugene T. Ek
- Subjects
Orthopedic surgery ,medicine.medical_specialty ,Drill ,business.industry ,medicine.medical_treatment ,Arthroplasty ,Surgery ,Resection ,body regions ,medicine.anatomical_structure ,medicine ,otorhinolaryngologic diseases ,Technical Note ,Orthopedics and Sports Medicine ,Olecranon fossa ,Elbow arthritis ,Fenestration ,business ,Coronoid fossa ,RD701-811 - Abstract
The Outerbridge-Kashiwagi procedure, or ulnohumeral arthroplasty, was described in 1978 as a method of treating elbow arthritis by creating a fenestration in the olecranon fossa. This fenestration diminishes the likelihood of recurrent spurs in the olecranon fossa and coronoid fossa, without loss of structural bony strength. Arthroscopic techniques have now been developed to perform this procedure. We describe an efficient method of creating the fenestration between the olecranon fossa and coronoid fossa during an arthroscopic ulnohumeral arthroplasty, or Outerbridge-Kashiwagi procedure, that also reduces the amount of residual bone debris produced during the resection.
- Published
- 2015
42. Latissimus Dorsi and Teres Major Transfer With Reverse Shoulder Arthroplasty Restores Active Motion and Reduces Pain for Posterosuperior Cuff Dysfunction
- Author
-
Laurence D. Higgins, Eugene T. Ek, Jon J.P. Warner, Jeffrey D. Tompson, Kirk E. Cahill, and Lewis L. Shi
- Subjects
musculoskeletal diseases ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Tendon Transfer ,Reverse shoulder ,Arthroplasty ,Rotator Cuff ,Tendon transfer ,Clinical Research ,medicine ,Humans ,Pain Management ,Orthopedics and Sports Medicine ,Rotator cuff ,business.industry ,food and beverages ,General Medicine ,Anatomy ,musculoskeletal system ,Surgery ,body regions ,medicine.anatomical_structure ,Cuff ,Orthopedic surgery ,Female ,Joint Diseases ,Range of motion ,business ,Teres major - Abstract
Background In patients with rotator cuff dysfunction, reverse shoulder arthroplasty can restore active forward flexion, but it does not provide a solution for the lack of active external rotation because of infraspinatus and the teres minor dysfunction. A modified L’Episcopo procedure can be performed in the same setting wherein the latissimus dorsi and teres major tendons are transferred to the lateral aspect of proximal humerus in an attempt to restore active external rotation.
- Published
- 2015
43. Comparison Between Triple-Tapered and Double-Tapered Cemented Femoral Stems in Total Hip Arthroplasty
- Author
-
Peter F. M. Choong and Eugene T. Ek
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,Early results ,business.industry ,Aseptic loosening ,medicine ,Orthopedics and Sports Medicine ,Prospective cohort study ,business ,Total hip arthroplasty ,Surgery - Abstract
A prospective study was conducted comparing the early clinical and radiological results between the triple-tapered C-Stem (DePuy International, Leeds, UK) and the double-tapered Exeter Universal (Stryker Howmedica Osteonics, Mahwah, NJ) in cemented total hip arthroplasty. A total of 192 patients (200 hips) received the C-Stem and 189 patients (205 hips) received the Exeter Universal. Average follow-up was 29 and 31 months in the C-Stem and Exeter groups, respectively. From the short-term results, we found similar mean improvements in clinical scores and no difference was noted in the incidence of complications. Average subsidence was comparable (C-Stem, 0.77 mm +/- 0.56; Exeter, 0.82 +/- 0.63). Radiolucencies in the cement-stem and cement-bone interfaces were seen primarily in the proximal zones in both groups. No stems were considered at risk of aseptic loosening and the extent of proximal femoral resorption was comparable.
- Published
- 2005
44. Fixation of Ultrasmall Proximal Pole Scaphoid Fractures Using Bioabsorbable Osteochondral Fixation Nails
- Author
-
Eugene T. Ek and Kemble K. Wang
- Subjects
Male ,medicine.medical_specialty ,Nonunion ,Scaphoid fracture ,Bone Nails ,030230 surgery ,Screw fixation ,Fracture Fixation, Internal ,Fractures, Bone ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,Absorbable Implants ,medicine ,Humans ,Orthopedics and Sports Medicine ,Surgical treatment ,Scaphoid Bone ,030222 orthopedics ,business.industry ,Middle Aged ,Scapholunate ligament ,medicine.disease ,Surgery ,Tomography, X-Ray Computed ,business ,Osteochondral fracture - Abstract
Surgical treatment of ultrasmall proximal pole scaphoid fractures poses a number of challenges. The fragment may be too small to fix with conventional headless screw fixation owing to the high risk of fragmentation upon insertion. However, excision of the fragment risks compromising the scapholunate ligament complex and also exposes the radioscaphoid joint to potential degenerative changes. Under these circumstances, we describe the use of bioabsorbable osteochondral fixation nails that allows stable low-profile fixation while minimizing the risk of fracturing the proximal pole.
- Published
- 2017
45. Vascular anomalies of the hand and wrist
- Author
-
Eugene T. Ek, Michelle G. Carlson, and Nina Suh
- Subjects
Diagnostic Imaging ,medicine.medical_specialty ,business.industry ,Vascular Malformations ,medicine.medical_treatment ,Arterial Embolization ,Ischemia ,Wrist ,medicine.disease ,Hand ,Surgery ,Lesion ,medicine.anatomical_structure ,Lymphatic system ,Blood loss ,Sclerotherapy ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Involution (medicine) ,medicine.symptom ,business - Abstract
Vascular malformations of the hand and wrist are uncommon. They develop from aberrations in angiogenic signaling during vascular development. Unlike hemangiomas, which are characterized by biphasic growth and slow spontaneous involution, vascular malformations continue to grow proportionally with the child. Management is dictated by classification of the vascular malformations, which is based on flow characteristics (ie, low, high) and predominant cell type (ie, venous, lymphatic, capillary, combined, arteriovenous). Initial management is conservative, with the goal of providing relief from pain and swelling. Sclerotherapy, laser treatment, and arterial embolization may be beneficial in well-selected patients. Surgery is indicated in cases of persistent pain and uncontrolled limb swelling leading to functional impairment and/or neurologic compression. The goals of surgery are to excise as much of the lesion as possible while avoiding injury to adjacent nerves, minimizing blood loss, and preventing distal limb ischemia. This mandates careful preoperative planning and meticulous technique. Adjuvant treatments may be warranted, as in the case of preoperative embolization in patients with high-flow lesions.
- Published
- 2014
46. Failure of the lesser tuberosity osteotomy after total shoulder arthroplasty
- Author
-
Eugene T. Ek, Lewis L. Shi, Jimmy J. Jiang, and Laurence D. Higgins
- Subjects
Adult ,Male ,Reoperation ,medicine.medical_specialty ,Visual analogue scale ,medicine.medical_treatment ,Elbow ,Osteotomy ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Lesser Tuberosity ,Treatment Failure ,Arthroplasty, Replacement ,Range of Motion, Articular ,Pain Measurement ,business.industry ,Shoulder Joint ,General Medicine ,Humerus ,Middle Aged ,Arthroplasty ,Surgery ,Radiography ,medicine.anatomical_structure ,Minor trauma ,Complication ,business ,Body mass index ,Follow-Up Studies - Abstract
Background Lesser tuberosity osteotomy (LTO) as an approach during total shoulder arthroplasty (TSA) is a reliable technique with strong biomechanical fixation and a low failure rate. Complications have been infrequently reported in the literature. Methods We report a case series of 5 patients who sustained failure of the LTO repair after primary TSA. The data on the patient demographic characteristics, surgical technique, postoperative care, revision surgery, and clinical outcomes are reported. Results The mean age of the 5 patients was 52 years, all patients were men, and the mean body mass index was 28 kg/m 2 . They were followed up for a mean of 29 months (range, 24-38 months). The mean time from initial TSA to diagnosis of LTO failure was 9 weeks (range, 5-12 weeks). Two patients reported no trauma, 2 had minor trauma (using a pulley, rolling over in bed), and 1 sustained a fall. At the latest follow-up, the mean visual analog scale; Single Assessment Numeric Evaluation; University of California, Los Angeles; and American Shoulder and Elbow Surgeons scores were 4 (range, 0-6), 48 (range, 20-70), 19 (range, 11-22), and 63 (range, 48-83), respectively. Only 1 patient required no additional procedures beyond the revision LTO repair. Another patient required a second revision LTO repair. The remaining 3 patients either underwent or were recommended to undergo reverse arthroplasty. Conclusion Failure of the LTO repair after TSA may possibly be an under-reported complication that is associated with poor clinical outcomes and limited options for revision surgery. In patients with a high risk of LTO failure, considerations should be made to augment the LTO repair during the index TSA procedure.
- Published
- 2014
47. Comparisons of preoperative three-dimensional planning and surgical reconstruction in primary cementless total hip arthroplasty
- Author
-
Stéphane Cherix, Eugene T. Ek, Hannes A. Rüdiger, and Hassen Hassani
- Subjects
Male ,medicine.medical_specialty ,Arthroplasty, Replacement, Hip ,Computed tomography ,Imaging, Three-Dimensional ,Implant size ,Femoral offset ,Preoperative Care ,Image Processing, Computer-Assisted ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Femur ,Aged ,Reproducibility ,medicine.diagnostic_test ,business.industry ,Leg length ,Middle Aged ,Leg Length Inequality ,Surgery, Computer-Assisted ,Female ,Hip Joint ,Radiology ,Anterior approach ,Hip Prosthesis ,Joint Diseases ,business ,Three dimensional planning ,Nuclear medicine ,Tomography, X-Ray Computed ,Total hip arthroplasty - Abstract
Reconstruction of important parameters such as femoral offset and torsion is inaccurate, when templating is based on plain x-rays. We evaluate intraoperative reproducibility of pre-operative CT-based 3D-templating in a consecutive series of 50 patients undergoing primary cementless THA through an anterior approach. Pre-operative planning was compared to a postoperative CT scan by image fusion. The implant size was correctly predicted in 100% of the stems, 94% of the cups and 88% of the heads (length). The difference between the planned and the postoperative leg length was 0.3 + 2.3 mm. Values for overall offset, femoral anteversion, cup inclination and anteversion were 1.4 mm ± 3.1, 0.6° ± 3.3°, −0.4° ± 5° and 6.9° ± 11.4°, respectively. This planning allows accurate implant size prediction. Stem position and cup inclination are accurately reproducible.
- Published
- 2013
48. Hand and wrist injuries in golf
- Author
-
Nina Suh, Andrew J. Weiland, and Eugene T. Ek
- Subjects
medicine.medical_specialty ,business.industry ,Hand Injuries ,Wrist ,Wrist Injuries ,Wrist injury ,Diagnosis, Differential ,medicine.anatomical_structure ,Physical medicine and rehabilitation ,medicine ,Golf ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Lumbar spine ,In patient ,business ,human activities ,Golf club ,Amateur - Abstract
T HE GAME OF GOLF HAS SEEN substantial growth on a global scale over the last few decades. With more than 60 million players worldwide, it has become a sport that has transcended socioeconomic class, sex, and age. Therefore, the development of golf-related injuries is becoming increasingly prevalent in patients of all ages and golfing ability. It is a commonmisperception that the golf swing is a seemingly benign and low physical demand activity. However, on careful examination, it is composed of a series of coordinated and synchronized movements of the entire body that allows the golf club to generate speeds in excess of 100 mph and launch the ball more than 300 yards. For both professional and amateur golfers, injuries to the hand and wrist are extremely common, and the hand and wrist are the most frequently affected sites, following the lumbar spine. Professional and high-level golfers most often sustain overuse injuries as a result of repetitive swings from frequent practice sessions. Although amateur golfers may also sustain such injuries, the more common mechanisms observed are poor swing mechanics, overzealous playing, or a sudden traumatic event such as hitting a tree or the ground awkwardly.
- Published
- 2013
49. A Biomechanical Study of 3 Types of Scaphoid Fixation in a Fracture Non-union Model
- Author
-
Avanthi Mandaleson, Eugene T. Ek, Craig Lewis, Steven Tham, and David C. Ackland
- Subjects
Clinical study ,Orthodontics ,030222 orthopedics ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,business.industry ,Medicine ,Orthopedics and Sports Medicine ,Surgery ,030230 surgery ,business ,Fracture non union - Published
- 2016
50. Reverse total shoulder arthroplasty for massive irreparable rotator cuff tears in patients younger than 65 years old: results after five to fifteen years
- Author
-
Eugene T. Ek, Lisa Neukom, Sabrina Catanzaro, and Christian Gerber
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,Shoulders ,medicine.medical_treatment ,Rotator Cuff Injuries ,Rotator Cuff ,Medicine ,Humans ,Orthopedics and Sports Medicine ,In patient ,Rotator cuff ,Risks and benefits ,Arthroplasty, Replacement ,Range of Motion, Articular ,business.industry ,Shoulder Joint ,Arthritis ,Age Factors ,General Medicine ,Recovery of Function ,Middle Aged ,Arthroplasty ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Tears ,Constant score ,Shoulder joint ,Female ,business ,Follow-Up Studies - Abstract
The role of reverse shoulder arthroplasty (RTSA) in the relatively young individual is currently unclear. Our study evaluates the midterm to long-term results of RTSA for patients aged younger than 65 years with pseudoparalysis secondary to massive irreparable rotator cuff tears, with or without arthritis.Between 1997 and 2006, 46 RTSAs (41 patients) were performed. Mean age was 60 years (range, 46-64 years). At the latest follow-up, 5 patients had died and 1 was lost, leaving 35 patients (40 shoulders) with a mean follow-up of 93 months (range, 60-171 months).The mean relative Constant score increased from 34% to 74% (P .0001) and the subjective shoulder value improved from 23% to 66% (P .0001). Significant improvements were seen in active forward elevation (72° to 119°), pain scores, and strength (P .001). One or more complications occurred in 15 shoulders (37.5%), with 6 failures (15%) resulting in removal or conversion to hemiarthroplasty (3 with infection, 3 with glenoid loosening). Ten shoulders (25%) underwent partial or total component exchange, conversion to hemiarthroplasty, or removal. Of the 15 patients who developed complications, 9 did not require prosthesis removal or conversion and functional outcome and subjective shoulder value were similar to those with no complications (P .4).RTSA in younger patients provides significant subjective improvement and substantial gain in overall function, which is maintained up to 10 years. Although the complication rate is high, most can be treated successfully without compromise to clinical outcome. However, it is imperative that the high complication rate is explained to patients, with the risks and benefits carefully considered.
- Published
- 2012
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