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A series of new adamantyl-oligoethyleneglycol-fullerene hybrids was prepared via Bingel-Hirsch functionalization of the C60 fullerene with various adamantyl-oligoethyleneglycol malonates. As NMDA-targeted antioxidants, these compounds may have the potential to be developed as therapeutic agents for the treatment of neurological disorders. [ABSTRACT FROM AUTHOR]

Highlights: [•] New soil remediation process using phase transition of partially miscible solvents. [•] Design and synthesis of new bio-degradable, organic soluble chelating agents. [•] Feasibility tests of the process on authentically polluted sediments and sludge. [•] Simultaneous removal of toxic metals and organic pollutants was demonstrated. [Copyright &y& Elsevier]

The catalytic reduction of nitrate by molybdo-enzymes plays a central role in the global biological cycle of nitrogen. However, the use of nitrates as oxidants in synthetic organic chemistry is very limited and typically requires very strong acidic and other extreme reaction conditions. We have developed a highly chemoselective and efficient catalytic process for the sulfoxidation of thioethers and arylthioethers containing boronic acid or boronic ester functional groups, using nitrate salts as oxidants. This homogeneous catalytic reaction was carried out in acetonitrile, where die MoO2Cl2(OPPh3)2 complex 1 or a mixture of complex 1 with Cu(NO3)2 were used as catalysts. We examined the reaction mechanism using ¹H, 15N, and 31P NMR techniques and 18O-labeled sodium nitrate (NaN18 O3) and show that the thioethers are oxidized by nitrate, generating nitrite. Our work adds to the existing chemical transformations available for organoboron compounds, providing straightforward accessibility to a variety of new substrates that could be suitable for Suzuki cross-coupling chemistry. [ABSTRACT FROM AUTHOR]