4 results on '"Schulz-Rothe, Sylvia"'
Search Results
2. Eine Monitoring-Liste für ein hausärztliches Case Management bei oraler Antikoagulation
- Author
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Ulrich, Lisa-Rebekka, Petersen, Juliana J., Mergenthai, Karola, Roehl, Ina, Rauck, Sandra, Erler, Antje, Kemperdick, Birgit, Schulz-Rothe, Sylvia, Gerlach, Ferdinand M., and Siebenhofer, Andrea
- Published
- 2013
- Full Text
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3. Does a complex intervention increase patient knowledge about oral anticoagulation? - a cluster-randomised controlled trial.
- Author
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Maikranz, Verena, Siebenhofer, Andrea, Ulrich, Lisa-R., Mergenthal, Karola, Schulz-Rothe, Sylvia, Kemperdick, Birgit, Rauck, Sandra, Pregartner, Gudrun, Berghold, Andrea, Gerlach, Ferdinand M., and Petersen, Juliana J.
- Subjects
ATRIAL fibrillation treatment ,THROMBOSIS prevention ,ANTICOAGULANTS ,DRUGS ,DRUG prescribing ,FAMILY medicine ,ORAL drug administration ,PATIENT compliance ,PATIENT education ,PRIMARY health care ,QUESTIONNAIRES ,RESEARCH funding ,HEALTH self-care ,VITAMIN K ,PHYSICIAN practice patterns ,RANDOMIZED controlled trials ,SOCIAL services case management ,CONTROL groups ,ACQUISITION of data ,PATIENT selection ,HEALTH literacy ,MEDICAL offices ,OFFICE management ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background: Oral anticoagulation therapy (OAT) is a challenge in general practice, especially for high-risk groups such as the elderly. Insufficient patient knowledge about safety-relevant aspects of OAT is considered to be one of the main reasons for complications. The research question addressed in this manuscript is whether a complex intervention that includes practice-based case management, self-management of OAT and additional patient and practice team education improves patient knowledge about anticoagulation therapy compared to a control group of patients receiving usual care (as a secondary objective of the Primary Care Management for Optimised Antithrombotic Treatment (PICANT) trial). Methods: The cluster-randomised controlled PICANT trial was conducted in 52 general practices in Germany, between 2012 and 2015. Trial participants were patients with a long-term indication for oral anticoagulation. A questionnaire was used to assess knowledge at baseline, after 12, and after 24 months. The questionnaire consists of 13 items (with a range of 0 to 13 sum-score points) covering topics related to intervention. Differences in the development of patient knowledge between intervention and control groups compared to baseline were assessed for each follow-up by means of linear mixed-effects models. Results: Seven hundred thirty-six patients were included at baseline, of whom 95.4% continued to participate after 12 months, and 89.3% after 24 months. The average age of patients was 73.5 years (SD 9.4), and they mainly suffered from atrial fibrillation (81.1%). Patients in the intervention and control groups had similar knowledge about oral anticoagulation at baseline (5.6 (SD 2.3) in both groups). After 12 months, the improvement in the level of knowledge (compared to baseline) was significantly larger in the intervention group than in the control group (0.78 (SD 2.5) vs. 0.04 (SD 2.3); p = 0.0009). After 24 months, the difference between both groups was still statistically significant (0.6 (SD 2.6) vs. -0.3 (SD 2.3); p = 0.0001). Conclusion: Since this intervention was effective, it should be established in general practice as a means of improving patient knowledge about oral anticoagulation. Trial registration: Current controlled trials ISRCTN41847489; Date of registration: 13/04/2012 [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
4. Anticoagulant treatment in German family practices - screening results from a cluster randomized controlled trial.
- Author
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Ulrich, Lisa-R., Mergenthal, Karola, Petersen, Juliana J., Roehl, Ina, Rauck, Sandra, Kemperdick, Birgit, Schulz-Rothe, Sylvia, Berghold, Andrea, and Siebenhofer, Andrea
- Subjects
THROMBOEMBOLISM prevention ,ANTICOAGULANTS ,DRUG prescribing ,MEDICATION errors ,PRIMARY health care ,RESEARCH funding ,STATISTICAL sampling ,PHYSICIAN practice patterns ,RANDOMIZED controlled trials ,DATA analysis software - Abstract
Background Oral anticoagulation (OAC) with coumarins and new anticoagulants are highly effective in preventing thromboembolic complications. However, some studies indicate that over- and under-treatment with anticoagulants are fairly common. The aim of this paper is to assess the appropriateness of treatment in patients with a long-term indication for OAC, and to describe the corresponding characteristics of such patients on the basis of screening results from the cluster randomized PICANT trial. Methods Randomly selected family practices in the federal state of Hesse, Germany, were visited by study team members. Eligible patients were screened using an anonymous patient list that was generated by the general practitioners' software according to predefined instructions. A documentation sheet was filled in for all screened patients. Eligible patients were classified into 3 categories (1: patients with a long-term indication for OAC and taking anticoagulants, 2: patients with a long-term indication for OAC but not taking anticoagulants, 3: patients without a long-term indication for OAC but taking an anticoagulant on a permanent basis). IBM SPSS Statistics 20 was used for descriptive statistical analysis. Results We screened 2,036 randomly selected, potentially eligible patients from 52 family practices. 275 patients could not be assigned to one of the 3 categories and were therefore not considered for analysis. The final study sample comprised 1,761 screened patients, 1,641 of whom belonged to category 1, 78 to category 2, and 42 to category 3. INR values were available for 1,504 patients of whom 1,013 presented INR values within their therapeutic ranges. The majority of screened patients had very good compliance, as assessed by the general practitioner. New antithrombotic drugs were prescribed in 6.1% of cases. Conclusions The screening results showed that a high proportion of patients were receiving appropriate anticoagulation therapy. The numbers of patients with a long-term indication for OAC therapy that were not receiving oral anticoagulants, and without a long-term indication that were receiving OAC, were considerably lower than expected. Most patients take coumarins, and the quality of OAC control is reasonably high. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
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