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Aims: This review examines the Current State of the Integrated Healthcare approach and assesses the impact of integrated care models on patient health outcomes. Methodology: A systematic review using PubMed database and Google Scholar database. Using period 2019-2023 and keywords Clinical Medicine AND Diagnosis AND Treatment AND Integrated Approach and "integrated care" AND "diagnosis and treatment" AND "clinical medicine" AND "multidisciplinary care" were employed to identify relevant studies from PubMed and Google Scholar. Finally, 18 articles were sampled. Results: The systematic literature review on integrated diagnosis and therapy in clinical medicine shows many study designs and sample sizes. RCTs, the gold standard, are included in the review, along with Prospective Cohort Studies, Retrospective Studies, Cross-Sectional Studies, and Post-hoc Analyses. Some studies have large populations and rich datasets, whereas others have smaller samples. These studies provide varied approaches and timeframes for applying the integrated approach in clinical practice and discuss integrated healthcare approaches that use multidisciplinary teams, innovative technologies, and targeted interventions to treat chronic disorders and multi-morbidities. Integrated healthcare enhances patient outcomes, adherence to recommendations, and quality of life, emphasizing the need for tailored care in modern medicine. Scientific Novelty: Exploring a complex, integrated clinical medicine diagnosis and treatment approach to find patient care solutions. Conclusion: Clinical medicine's integrated diagnosis and treatment strategy is dynamic and promising. It can improve patient care, lower healthcare costs, and improve the quality of life for people with diverse health issues. [ABSTRACT FROM AUTHOR]