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Purpose: To determine the normative values of the peripapillary retinal nerve fiber layer (RNFL), macular thickness, and macular volume in healthy children using spectral-domain optical coherence tomography (SD-OCT) and analyze the correlation of such values with age, refraction error, and biometric measurements., Design: Observational case series., Methods: This institutional study involved 107 eyes from 107 healthy pediatric patients (54 female, 53 male) with ages between 6 and 16 years. After the biometric measurements and refractive error values (in spherical equivalent) of the cases were obtained, the peripapillary RNFL, macular thickness, and macular volume values were calculated using the Spectralis OCT device., Results: Among the study group, with an average age of 10.46 ± 2.94 years, the average axial length (AL) was 23.33 ± 0.89 mm; the average spherical equivalent (SE) value was -0.27 ± 0.99 diopter. The average peripapillary RNFL thickness was 106.45 ± 9.41 μm; the average macular thickness was 326.44 ± 14.17 μm; and the average macular volume was 0.257 ± 0.011 mm(3). The aforementioned OCT measurements were not significantly correlated with age, SE, or AL values (P > .05 for all)., Conclusions: This study reports SD-OCT findings among healthy pediatric cases. SD-OCT can be reliably used for pediatric patients because of its short exposure time and high degree of image resolution., (Copyright © 2012 Elsevier Inc. All rights reserved.)

Purpose: To determine the efficacy of Heidelberg Retinal Tomography II (HRTII) parameters in differentiating normal eyes from eyes with early or moderate glaucomatous damage., Methods: HRTII tests were performed on 70 eyes of 70 patients with early or moderate glaucomatous damage, and 70 eyes of 70 healthy subjects. HRTII stereometric parameters, global and sectorial rim area parameters were recorded. Sensitivity and specificity of each parameter were calculated. Cases were divided into three groups according to disc size as large, medium and small, and mean values of parameters in glaucoma and control groups were compared., Results: Mean disc area was larger in the glaucoma group (P < 0.05). There was a significant difference between the two groups for all stereometric parameters, except height variation contour, mean retinal nerve fibre layer thickness and retinal nerve fibre layer cross-sectional area stereometric parameters. There was also a significant difference between the groups for global, temporal, superior temporal and inferior temporal rim area parameters. In small discs, however, this difference disappeared in all parameters except temporal rim area and superior temporal rim area sectorial parameters. When all the cases were included, the quartet parameters having the highest specificity (80%) and sensitivity (74.3%) were cup volume, rim volume, cup shape measure and height variation contour parameters., Conclusion: Some HRTII parameters have better sensitivity and specificity than the others. It is necessary to pay special attention in evaluating small discs.