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Your search keyword '"Rinella, Nicholas T"' showing total 2 results
Start Over Author "Rinella, Nicholas T" Topic opthalmology and optometry
2 results on '"Rinella, Nicholas T"'

1. Quantifying choriocapillaris hypoperfusion in patients with choroidal neovascularization using swept-source OCT angiography

Author

Keiner, Cathrine M, Zhou, Hao, Zhang, Qinqin, Wang, Ruikang K, Rinella, Nicholas T, Oldenburg, Catherine E, Duncan, Jacque L, and Schwartz, Daniel M

Subjects
Biomedical and Clinical Sciences, Ophthalmology and Optometry, Neurosciences, Clinical Research, Neurodegenerative, Biomedical Imaging, Macular Degeneration, Aging, Eye Disease and Disorders of Vision, 2.1 Biological and endogenous factors, Eye, flow void, AMD, OCT angiography, OCTA, Opthalmology and Optometry, Ophthalmology and optometry
Abstract

PurposeTo compare choriocapillaris flow voids (FV) in patients with neovascular age-related macular degeneration (AMD) with age-matched normal controls using swept-source optical coherence tomography angiography (SS-OCTA).Patients and methodsEleven eyes of 11 subjects with neovascular AMD and 11 eyes of 11 age-similar normal subjects were imaged using SS-OCTA with a 6x6mm scanning pattern. Choriocapillaris FV, defined as a percentage of regions determined to have flow deficits divided by the total scanned region, was measured using a one standard deviation thresholding algorithm developed from a database of age-similar normal subjects.ResultsChoriocapillaris FV was more extensive in patients with choroidal neovascularization (CNV) compared to age-similar normal subjects (FV: 20.56±4.95, 95% CI: 17.64-23.49 vs FV: 10.95±2.08, 95% CI: 9.73-12.18, respectively; P=0.0001). FV within a two-degree margin surrounding CNV in wet AMD subjects (FV: 35.04±9.34; 95% CI: 29.52-40.56) was increased compared to normal subjects (P

Published
2019

2. Quantifying choriocapillaris hypoperfusion in patients with choroidal neovascularization using swept-source OCT angiography

Author

Keiner,Cathrine M, Zhou,Hao, Zhang,Qinqin, Wang,Ruikang K, Rinella,Nicholas T, Oldenburg,Catherine E, Duncan,Jacque L, and Schwartz,Daniel M

Subjects
Aging, genetic structures, Prevention, OCT angiography, flow void, Clinical Ophthalmology, AMD, Neurodegenerative, eye diseases, Macular Degeneration, Clinical Research, Opthalmology and Optometry, Biomedical Imaging, 2.1 Biological and endogenous factors, sense organs, Aetiology, OCTA, Eye Disease and Disorders of Vision
Abstract

Cathrine M Keiner,1 Hao Zhou,2 Qinqin Zhang,2 Ruikang K Wang,2 Nicholas T Rinella,1 Catherine E Oldenburg,1,3 Jacque L Duncan,1 Daniel M Schwartz11Department of Ophthalmology, University of California, San Francisco, CA, USA; 2Department of Bioengineering, University of Washington, Seattle, WA, USA; 3Francis I. Proctor Foundation, University of California, San Francisco, CA, USACorrespondence: Daniel M SchwartzDepartment of Ophthalmology, University of California, 10 Koret Way, San Francisco, CA 94117, USATel +1 415 476 1152Email dan.schwartz@ucsf.eduPurpose: To compare choriocapillaris flow voids (FV) in patients with neovascular age-related macular degeneration (AMD) with age-matched normal controls using swept-source optical coherence tomography angiography (SS-OCTA).Patients and methods: Eleven eyes of 11 subjects with neovascular AMD and 11 eyes of 11 age-similar normal subjects were imaged using SS-OCTA with a 6x6mm scanning pattern. Choriocapillaris FV, defined as a percentage of regions determined to have flow deficits divided by the total scanned region, was measured using a one standard deviation thresholding algorithm developed from a database of age-similar normal subjects.Results: Choriocapillaris FV was more extensive in patients with choroidal neovascularization (CNV) compared to age-similar normal subjects (FV: 20.56±4.95, 95% CI: 17.64–23.49 vs FV: 10.95±2.08, 95% CI: 9.73–12.18, respectively; P=0.0001). FV within a two-degree margin surrounding CNV in wet AMD subjects (FV: 35.04±9.34; 95% CI: 29.52–40.56) was increased compared to normal subjects (P

Published
2019

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